(44 nodes) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site network (Methanococcus maripaludis S2)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	frcG	Coenzyme F420-reducing hydrogenase subunit gamma; Cytoplasmic, selenium independent; Citation: Muth, E. et al. 1987. Eur. J. Biochem. 169:571-7. Berghofer, Y. et al. 1994. Mol. Gen. Genet. 242:369-373. Halboth,S., Klein,A. (242 aa)
	vhcB	Coenzyme F420-non-reducing hydrogenase subunit beta; Selenium independent; Citation: Berghofer, Y. et al. 1994. Mol. Gen. Genet. 242:369-373. Hedderich, R. et al. 1992. FEBS Lett. 298:65-8. Halboth,S., Klein,A. (. (397 aa)
	hdrA	Heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (654 aa)
	MMP0979	Conserved archaeal protein; Putative electron transport protein for CO dehydrogenase, iron-sulfur binding domain; Citation: Anderson, I. and W. B. Whitman, unpublished. (154 aa)
	cdhA	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (778 aa)
	thyA	Thymidylate synthase; Citation: Xu et al., Nature Structural. Biol. 6, 750 (1999). (291 aa)
	hdrC2	Heterodisulfide reductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrC family. (184 aa)
	MMP1067	Uncharacterized iron-sulfur protein MMP1067; Succinate dehydrogenase/fumarate reductase iron-sulfur subunit // Methanosarcina type heterodisulfide reductase subunit D; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (494 aa)
	fdxA	Ferredoxin. (81 aa)
	hdrC1	Heterosulfide reductase, subunit C1; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrC family. (192 aa)
	fwdF	Tungsten containing formylmethanofuran dehydrogenase, subunit F; Citation: FEBS Lett. 1989 253: 226-30; Eur. J. Biochem. 1996 242: 156-162. (352 aa)
	fwdG	Tungsten containing formylmethanofuran dehydrogenase, subunit G; Citation: FEBS Lett. 1989 253: 226-30; Eur. J. Biocehem. 199642: 156-162. (80 aa)
	vorC	2-oxoisovalerate oxidoreductase subunit gamma; Citation: Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. (79 aa)
	fdhB-2	Formate dehydrogenase beta subunit. (387 aa)
	MMP1311	Ferredoxin. (52 aa)
	MMP1329	Ferredoxin; Contains a 4Fe-4S binding domain. (62 aa)
	MMP1358	Ferredoxin. (132 aa)
	fruG	Coenzyme F420-reducing hydrogenase subunit gamma; Membrane-bound, selenium dependent; Citation: Brodersen, J. et al. 1999. Arch. Microbiol. 171:115-21. Halboth,S., Klein,A. (1992) Mol. Gen. Genet. 233:217-224. (228 aa)
	ehaP	Polyferredoxin; Citation: J. Mol. Evol. 1985 22: 20-31; J. Mol. Evol. 1989 29: 246-54. (393 aa)
	ehaQ	Conserved hypothetical protein; Citation: Tersteegen, A. and R. Hedderich. 1999. Eur. J. Biochem. 264:930-43. (161 aa)
	ehaR	Conserved hypothetical protein; Citation: Tersteegen, A. and R. Hedderich. 1999. Eur. J. Biochem. 264:930-43. (252 aa)
	porF	Conserved archaeal protein, pyruvate oxidoreductase-associated; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (138 aa)
	porE	Conserved archaeal protein, pyruvate oxidoreductase-associated; Putative electron transport protein for pyruvate oxidoreductase; Citation: Lin, WC et al, Arch Microbiol 179:444 (2003). (167 aa)
	porD	Pyruvate oxidoreductase (synthase) subunit delta; Citation: Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8; Lin, WC et al, Arch Microbiol 179:444 (2003). (85 aa)
	ehbL	Ferredoxin; Citation: Tersteegen, A. and R. Hedderich. 1999. Eur. J. Biochem. 264:930-43. (170 aa)
	ehbK	Polyferredoxin; Citation: Tersteegen, A. and R. Hedderich. 1999. Eur. J. Biochem. 264:930-43. (481 aa)
	korD	2-oxoglutarate ferredoxin oxidoreductase, delta (ferredoxin) subunit; Citation: Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. (68 aa)
	hdrA-2	Heterodisulfide reductase, subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (658 aa)
	vhuB	Polyferredoxin, associated with F420-non-reducing hydrogenase; Selenium dependent; Citation: Hedderich, R. et al. 1992. FEBS Lett. 298:65-8. Reeve, J.N. et al. 1989. PNAS 86:3031-5. Halboth,S., Klein,A. (1992) Mol. Gen. (383 aa)
	gltB	Glutamate synthase; Citation: Nesbo CL, L'Haridon S, Stetter KO, Doolittle WF. (2001) Mol Biol Evol 18:362-75; Belongs to the glutamate synthase family. (510 aa)
	MMP0083	Conserved archaeal protein; Contains 4Fe-4S motif. (359 aa)
	MMP0098	Ferredoxin. (65 aa)
	MMP0104	Polyferredoxin. (205 aa)
	fdhB	Formate dehydrogenase beta subunit. (375 aa)
	MMP0208	Conserved hypothetical protein; Contains 4Fe-4S motif. (409 aa)
	iorA1	Indolepyruvate oxidoreductase subunit alpha 1; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (612 aa)
	MMP0382	RNase L inhibitor; Citation: J Bio Chem 270:13308-13317 1995. (590 aa)
	MMP0389	Ferredoxin. (54 aa)
	MMP0449	Ferredoxin. (281 aa)
	MMP0450	Ferredoxin. (285 aa)
	MMP0690	Polyferredoxin. (233 aa)
	MMP0722	Conserved Hypothetical Archael Protein. (210 aa)
	MMP0803	Conserved archaeal protein. (370 aa)
	MMP0808	Conserved hypothetical protein. (397 aa)

Your Current Organism:

Methanococcus maripaludis S2

NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MMP0083	MMP1067	MMP0083	MMP1067	Conserved archaeal protein; Contains 4Fe-4S motif.	Uncharacterized iron-sulfur protein MMP1067; Succinate dehydrogenase/fumarate reductase iron-sulfur subunit // Methanosarcina type heterodisulfide reductase subunit D; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.415
MMP0083	frcG	MMP0083	MMP0818	Conserved archaeal protein; Contains 4Fe-4S motif.	Coenzyme F420-reducing hydrogenase subunit gamma; Cytoplasmic, selenium independent; Citation: Muth, E. et al. 1987. Eur. J. Biochem. 169:571-7. Berghofer, Y. et al. 1994. Mol. Gen. Genet. 242:369-373. Halboth,S., Klein,A.	0.989
MMP0083	fruG	MMP0083	MMP1384	Conserved archaeal protein; Contains 4Fe-4S motif.	Coenzyme F420-reducing hydrogenase subunit gamma; Membrane-bound, selenium dependent; Citation: Brodersen, J. et al. 1999. Arch. Microbiol. 171:115-21. Halboth,S., Klein,A. (1992) Mol. Gen. Genet. 233:217-224.	0.990
MMP0083	fwdF	MMP0083	MMP1245	Conserved archaeal protein; Contains 4Fe-4S motif.	Tungsten containing formylmethanofuran dehydrogenase, subunit F; Citation: FEBS Lett. 1989 253: 226-30; Eur. J. Biochem. 1996 242: 156-162.	0.886
MMP0083	fwdG	MMP0083	MMP1246	Conserved archaeal protein; Contains 4Fe-4S motif.	Tungsten containing formylmethanofuran dehydrogenase, subunit G; Citation: FEBS Lett. 1989 253: 226-30; Eur. J. Biocehem. 199642: 156-162.	0.859
MMP0083	gltB	MMP0083	MMP0081	Conserved archaeal protein; Contains 4Fe-4S motif.	Glutamate synthase; Citation: Nesbo CL, L'Haridon S, Stetter KO, Doolittle WF. (2001) Mol Biol Evol 18:362-75; Belongs to the glutamate synthase family.	0.976
MMP0083	hdrA	MMP0083	MMP0825	Conserved archaeal protein; Contains 4Fe-4S motif.	Heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).	0.865
MMP0083	hdrA-2	MMP0083	MMP1697	Conserved archaeal protein; Contains 4Fe-4S motif.	Heterodisulfide reductase, subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).	0.865
MMP0083	hdrC1	MMP0083	MMP1154	Conserved archaeal protein; Contains 4Fe-4S motif.	Heterosulfide reductase, subunit C1; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrC family.	0.599
MMP0083	hdrC2	MMP0083	MMP1054	Conserved archaeal protein; Contains 4Fe-4S motif.	Heterodisulfide reductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrC family.	0.599
MMP0208	MMP0690	MMP0208	MMP0690	Conserved hypothetical protein; Contains 4Fe-4S motif.	Polyferredoxin.	0.526
MMP0208	MMP0803	MMP0208	MMP0803	Conserved hypothetical protein; Contains 4Fe-4S motif.	Conserved archaeal protein.	0.541
MMP0449	MMP0450	MMP0449	MMP0450	Ferredoxin.	Ferredoxin.	0.869
MMP0449	MMP0722	MMP0449	MMP0722	Ferredoxin.	Conserved Hypothetical Archael Protein.	0.418
MMP0449	frcG	MMP0449	MMP0818	Ferredoxin.	Coenzyme F420-reducing hydrogenase subunit gamma; Cytoplasmic, selenium independent; Citation: Muth, E. et al. 1987. Eur. J. Biochem. 169:571-7. Berghofer, Y. et al. 1994. Mol. Gen. Genet. 242:369-373. Halboth,S., Klein,A.	0.744
MMP0449	fruG	MMP0449	MMP1384	Ferredoxin.	Coenzyme F420-reducing hydrogenase subunit gamma; Membrane-bound, selenium dependent; Citation: Brodersen, J. et al. 1999. Arch. Microbiol. 171:115-21. Halboth,S., Klein,A. (1992) Mol. Gen. Genet. 233:217-224.	0.744
MMP0449	hdrC1	MMP0449	MMP1154	Ferredoxin.	Heterosulfide reductase, subunit C1; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrC family.	0.423
MMP0449	hdrC2	MMP0449	MMP1054	Ferredoxin.	Heterodisulfide reductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrC family.	0.423
MMP0450	MMP0449	MMP0450	MMP0449	Ferredoxin.	Ferredoxin.	0.869
MMP0450	frcG	MMP0450	MMP0818	Ferredoxin.	Coenzyme F420-reducing hydrogenase subunit gamma; Cytoplasmic, selenium independent; Citation: Muth, E. et al. 1987. Eur. J. Biochem. 169:571-7. Berghofer, Y. et al. 1994. Mol. Gen. Genet. 242:369-373. Halboth,S., Klein,A.	0.744