STRINGSTRING
ADINL_0776 ADINL_0776 hisH hisH ADINL_0023 ADINL_0023 hutI hutI hutG hutG ADINL_0035 ADINL_0035 aguA aguA def def folD folD purU purU ADINL_0194 ADINL_0194 purU-2 purU-2 tadA tadA lpxC lpxC cheB cheB ADINL_0729 ADINL_0729 ADINL_0756 ADINL_0756 alc alc ADINL_0777 ADINL_0777 ureC ureC ureB ureB ureA ureA pyrC pyrC ADINL_1035 ADINL_1035 pyrG pyrG ADINL_1098 ADINL_1098 ADINL_1112 ADINL_1112 dapE dapE ADINL_1159 ADINL_1159 ADINL_1198 ADINL_1198 ADINL_1218 ADINL_1218 purU-3 purU-3 ADINL_1300 ADINL_1300 cobB cobB folD-2 folD-2 ADINL_1647 ADINL_1647 ADINL_1768 ADINL_1768 ribA ribA ADINL_1790 ADINL_1790 nadE nadE ADINL_1820 ADINL_1820 cheB-2 cheB-2 purH purH folE2 folE2 ADINL_2080 ADINL_2080 ADINL_2101 ADINL_2101 ADINL_2103 ADINL_2103 cheD cheD cheB-3 cheB-3 cheD-2 cheD-2 dcd dcd cobB-2 cobB-2 folE folE glsA glsA hisI hisI ADINL_2777 ADINL_2777 ADINL_2892 ADINL_2892 ADINL_2895 ADINL_2895 ADINL_2900 ADINL_2900 ADINL_3117 ADINL_3117 ADINL_3129 ADINL_3129
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADINL_0776Ureidoglycolate hydrolase. (168 aa)
hisHImidazole glycerol phosphate synthase amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (215 aa)
ADINL_0023Gamma-glutamyl-GABA hydrolase. (282 aa)
hutIImidazolonepropionase. (404 aa)
hutGFormiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (318 aa)
ADINL_0035N-carbamoylputrescine amidase. (290 aa)
aguAAgmatine deiminase. (366 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (172 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (295 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (288 aa)
ADINL_0194Sel1-like protein. (132 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (289 aa)
tadAtRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (164 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (304 aa)
cheBChemotaxis response regulator protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (364 aa)
ADINL_0729Dihydroorotase. (427 aa)
ADINL_0756Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (431 aa)
alcAllantoicase; Belongs to the allantoicase family. (334 aa)
ADINL_0777Uricase (urate oxidase). (308 aa)
ureCUrease alpha subunit. (567 aa)
ureBUrease beta subunit; Belongs to the urease beta subunit family. (101 aa)
ureAUrease gamma subunit; Belongs to the urease gamma subunit family. (100 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (345 aa)
ADINL_1035Flagellar protein FlgJ. (348 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (542 aa)
ADINL_1098C-terminal domain of CinA type S; Protein Implicated in DNA repair function with RecA and MutS; Belongs to the CinA family. (164 aa)
ADINL_1112Deacetylase. (307 aa)
dapEN-succinyl-L,L-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (379 aa)
ADINL_1159N-acetylmuramoyl-L-alanine amidase. (469 aa)
ADINL_1198N-acetylmuramoyl-L-alanine amidase AmpD. (216 aa)
ADINL_1218Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (341 aa)
purU-3Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa)
ADINL_1300Putative deacylase. (347 aa)
cobBNAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily. (238 aa)
folD-2Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
ADINL_1647Hypothetical protein. (356 aa)
ADINL_1768Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (373 aa)
ribAGTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (184 aa)
ADINL_1790Lactam utilization protein LamB; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (246 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (542 aa)
ADINL_1820Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (244 aa)
cheB-2Chemotaxis response regulator protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (398 aa)
purHIMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. (527 aa)
folE2GTP cyclohydrolase I type 2; Converts GTP to 7,8-dihydroneopterin triphosphate. (315 aa)
ADINL_2080Glutamine amidotransferase, class I. (225 aa)
ADINL_2101Acetylornithine deacetylase. (423 aa)
ADINL_2103Deacetylase. (348 aa)
cheDChemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (204 aa)
cheB-3Chemotaxis response regulator protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (352 aa)
cheD-2Chemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (200 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (177 aa)
cobB-2NAD-dependent protein deacetylase of SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (290 aa)
folEGTP cyclohydrolase I type 1. (212 aa)
glsAGlutaminase; Belongs to the glutaminase family. (298 aa)
hisIPhosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (135 aa)
ADINL_2777Xaa-Pro aminopeptidase. (392 aa)
ADINL_2892Dihydropyrimidinase. (481 aa)
ADINL_2895Beta-ureidopropionase. (427 aa)
ADINL_2900Cytosine deaminase. (416 aa)
ADINL_3117L-asparaginase I, cytoplasmic. (342 aa)
ADINL_3129Dihydroorotase. (446 aa)
Your Current Organism:
Nitrincola lacisaponensis
NCBI taxonomy Id: 267850
Other names: ATCC BAA-920, DSM 16316, N. lacisaponensis, Nitrincola lacisaponensis Dimitriu et al. 2005, strain 4CA
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