(15 nodes) CBS domain superfamily network (Nitrincola lacisaponensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ADINL_1278	CBS domain protein. (137 aa)
	ADINL_1371	Arabinose 5-phosphate isomerase. (338 aa)
	ADINL_1530	Mg/Co/Ni transporter MgtE; Acts as a magnesium transporter. (458 aa)
	ADINL_1886	Putative signal-transduction protein containing cAMP-binding and CBS domains. (611 aa)
	ADINL_1901	Magnesium and cobalt efflux protein CorC. (280 aa)
	guaB	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (489 aa)
	ADINL_2075	cAMP-binding/CBS multi-domain protein; Putative signal-transduction protein containing cAMP-binding and CBS domains. (622 aa)
	ADINL_2742	Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s). (574 aa)
	ADINL_2885	Mg/Co/Ni transporter MgtE; Acts as a magnesium transporter. (447 aa)
	ADINL_0331	Hypothetical protein. (202 aa)
	ADINL_0645	Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s). (839 aa)
	ADINL_0911	Magnesium and cobalt efflux protein CorC. (423 aa)
	ADINL_0968	CBS domain protein. (128 aa)
	ADINL_0971	Hypothetical protein. (134 aa)
	ADINL_1196	CBS domain protein. (215 aa)

Your Current Organism:

Nitrincola lacisaponensis

NCBI taxonomy Id: 267850
Other names: ATCC BAA-920, DSM 16316, N. lacisaponensis, Nitrincola lacisaponensis Dimitriu et al. 2005, strain 4CA

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADINL_0331	ADINL_0968	ADINL_0331	ADINL_0968	Hypothetical protein.	CBS domain protein.	0.436
ADINL_0645	ADINL_2742	ADINL_0645	ADINL_2742	Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s).	Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s).	0.939
ADINL_0645	guaB	ADINL_0645	ADINL_1940	Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s).	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.875
ADINL_0968	ADINL_0331	ADINL_0968	ADINL_0331	CBS domain protein.	Hypothetical protein.	0.436
ADINL_0968	ADINL_0971	ADINL_0968	ADINL_0971	CBS domain protein.	Hypothetical protein.	0.736
ADINL_0968	ADINL_1278	ADINL_0968	ADINL_1278	CBS domain protein.	CBS domain protein.	0.431
ADINL_0968	ADINL_1371	ADINL_0968	ADINL_1371	CBS domain protein.	Arabinose 5-phosphate isomerase.	0.710
ADINL_0968	guaB	ADINL_0968	ADINL_1940	CBS domain protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.793
ADINL_0971	ADINL_0968	ADINL_0971	ADINL_0968	Hypothetical protein.	CBS domain protein.	0.736
ADINL_0971	guaB	ADINL_0971	ADINL_1940	Hypothetical protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.748
ADINL_1278	ADINL_0968	ADINL_1278	ADINL_0968	CBS domain protein.	CBS domain protein.	0.431
ADINL_1278	ADINL_1371	ADINL_1278	ADINL_1371	CBS domain protein.	Arabinose 5-phosphate isomerase.	0.693
ADINL_1278	ADINL_2742	ADINL_1278	ADINL_2742	CBS domain protein.	Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s).	0.709
ADINL_1278	guaB	ADINL_1278	ADINL_1940	CBS domain protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.459
ADINL_1371	ADINL_0968	ADINL_1371	ADINL_0968	Arabinose 5-phosphate isomerase.	CBS domain protein.	0.710
ADINL_1371	ADINL_1278	ADINL_1371	ADINL_1278	Arabinose 5-phosphate isomerase.	CBS domain protein.	0.693
ADINL_1371	ADINL_2742	ADINL_1371	ADINL_2742	Arabinose 5-phosphate isomerase.	Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s).	0.748
ADINL_1371	guaB	ADINL_1371	ADINL_1940	Arabinose 5-phosphate isomerase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.950
ADINL_1530	guaB	ADINL_1530	ADINL_1940	Mg/Co/Ni transporter MgtE; Acts as a magnesium transporter.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.443
ADINL_1886	guaB	ADINL_1886	ADINL_1940	Putative signal-transduction protein containing cAMP-binding and CBS domains.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.748