STRINGSTRING
fadA fadA tal tal cysG cysG ADINL_3126 ADINL_3126 ADINL_3125 ADINL_3125 ADINL_3124 ADINL_3124 ADINL_3123 ADINL_3123 ADINL_3122 ADINL_3122 ADINL_3114 ADINL_3114 ADINL_3113 ADINL_3113 cysD cysD cysN cysN rnfC rnfC ADINL_3094 ADINL_3094 ADINL_3080 ADINL_3080 ADINL_3077 ADINL_3077 ADINL_3068 ADINL_3068 accD accD ADINL_3052 ADINL_3052 asd asd ADINL_2983 ADINL_2983 ADINL_2963 ADINL_2963 mqo mqo ADINL_2935 ADINL_2935 ADINL_2932 ADINL_2932 ADINL_2897 ADINL_2897 ADINL_2884 ADINL_2884 nfuA nfuA ADINL_2860 ADINL_2860 dapA dapA tpiA tpiA ADINL_2809 ADINL_2809 gluQ gluQ ADINL_2797 ADINL_2797 hemL hemL ADINL_2778 ADINL_2778 thrB thrB phnX phnX ADINL_2729 ADINL_2729 ADINL_2719 ADINL_2719 ADINL_2718 ADINL_2718 ADINL_2717 ADINL_2717 ADINL_2716 ADINL_2716 ADINL_2696 ADINL_2696 ADINL_2676 ADINL_2676 ADINL_2662 ADINL_2662 gpmI gpmI ADINL_2643 ADINL_2643 ADINL_2612 ADINL_2612 ADINL_2608 ADINL_2608 ADINL_2593 ADINL_2593 ADINL_2586 ADINL_2586 ADINL_2581 ADINL_2581 ADINL_2574 ADINL_2574 ADINL_2564 ADINL_2564 ADINL_2516 ADINL_2516 ADINL_2512 ADINL_2512 ADINL_2462 ADINL_2462 ADINL_2449 ADINL_2449 ADINL_2447 ADINL_2447 ADINL_2423 ADINL_2423 ADINL_2391 ADINL_2391 ADINL_2383 ADINL_2383 pgi pgi ADINL_2360 ADINL_2360 ADINL_2340 ADINL_2340 ADINL_2337 ADINL_2337 ectC ectC ADINL_2335 ADINL_2335 ectA ectA sucD sucD sucC sucC ADINL_2321 ADINL_2321 ADINL_2320 ADINL_2320 ADINL_2319 ADINL_2319 ADINL_2318 ADINL_2318 ADINL_2317 ADINL_2317 ADINL_2316 ADINL_2316 ADINL_2315 ADINL_2315 ADINL_2314 ADINL_2314 ADINL_2310 ADINL_2310 ADINL_2288 ADINL_2288 ADINL_2277 ADINL_2277 ADINL_2270 ADINL_2270 ADINL_2206 ADINL_2206 ADINL_2205 ADINL_2205 ADINL_2204 ADINL_2204 ADINL_2202 ADINL_2202 ADINL_2201 ADINL_2201 ADINL_2186 ADINL_2186 ADINL_2185 ADINL_2185 ADINL_2183 ADINL_2183 ADINL_2102 ADINL_2102 ADINL_2101 ADINL_2101 ADINL_2027 ADINL_2027 ADINL_2025 ADINL_2025 ppc ppc ADINL_2004 ADINL_2004 ADINL_2002 ADINL_2002 ackA ackA ADINL_1996 ADINL_1996 ADINL_1988 ADINL_1988 ADINL_1987 ADINL_1987 fbp fbp ubiX ubiX ADINL_1966 ADINL_1966 ADINL_1958 ADINL_1958 ADINL_1942 ADINL_1942 ADINL_1912 ADINL_1912 acsA acsA bamB bamB ADINL_1839 ADINL_1839 ADINL_1838 ADINL_1838 glyA-2 glyA-2 ADINL_1742 ADINL_1742 ADINL_1741 ADINL_1741 ADINL_1740 ADINL_1740 ADINL_1655 ADINL_1655 ADINL_1654 ADINL_1654 ADINL_1643 ADINL_1643 folD-2 folD-2 ADINL_1621 ADINL_1621 ADINL_1594 ADINL_1594 nqrF nqrF ADINL_1558 ADINL_1558 ADINL_1551 ADINL_1551 ADINL_1549 ADINL_1549 ADINL_1546 ADINL_1546 ADINL_1518 ADINL_1518 ADINL_1511 ADINL_1511 ADINL_1506 ADINL_1506 ADINL_1505 ADINL_1505 ADINL_1501 ADINL_1501 ADINL_1495 ADINL_1495 ADINL_1490 ADINL_1490 ADINL_1488 ADINL_1488 gltX gltX ADINL_1446 ADINL_1446 ADINL_1405 ADINL_1405 ADINL_1400 ADINL_1400 ADINL_1348 ADINL_1348 ADINL_1320 ADINL_1320 ADINL_1318 ADINL_1318 ADINL_1315 ADINL_1315 ADINL_1313 ADINL_1313 ADINL_1312 ADINL_1312 ADINL_1311 ADINL_1311 ADINL_1310 ADINL_1310 ADINL_1308 ADINL_1308 ADINL_1306 ADINL_1306 ADINL_1305 ADINL_1305 ADINL_1304 ADINL_1304 ADINL_1303 ADINL_1303 ADINL_1302 ADINL_1302 ADINL_1301 ADINL_1301 ADINL_1300 ADINL_1300 ADINL_1274 ADINL_1274 ADINL_1273 ADINL_1273 ADINL_1272 ADINL_1272 ADINL_1268 ADINL_1268 ADINL_1263 ADINL_1263 ADINL_1256 ADINL_1256 glpE glpE ADINL_1225 ADINL_1225 ADINL_1223 ADINL_1223 ADINL_1222 ADINL_1222 ADINL_1212 ADINL_1212 ADINL_1211 ADINL_1211 ADINL_1210 ADINL_1210 ADINL_1209 ADINL_1209 ADINL_1202 ADINL_1202 ADINL_1201 ADINL_1201 mdh mdh ADINL_1180 ADINL_1180 ADINL_1172 ADINL_1172 queG queG ADINL_1146 ADINL_1146 pdxH pdxH fumC fumC ADINL_1129 ADINL_1129 dapD dapD dapE dapE ADINL_1106 ADINL_1106 ADINL_1102 ADINL_1102 eno eno accA accA ADINL_1047 ADINL_1047 ADINL_1014 ADINL_1014 ADINL_1002 ADINL_1002 hemA hemA prs prs ADINL_0987 ADINL_0987 ADINL_0978 ADINL_0978 ADINL_0977 ADINL_0977 ADINL_0953 ADINL_0953 ADINL_0939 ADINL_0939 ADINL_0922 ADINL_0922 ADINL_0921 ADINL_0921 dapB dapB ADINL_0862 ADINL_0862 ADINL_0843 ADINL_0843 ADINL_0837 ADINL_0837 glcB glcB ureA ureA ureB ureB ureC ureC ADINL_0793 ADINL_0793 ADINL_0784 ADINL_0784 ADINL_0777 ADINL_0777 alc alc ADINL_0774 ADINL_0774 ADINL_0769 ADINL_0769 srkA srkA ADINL_0760 ADINL_0760 ADINL_0759 ADINL_0759 ADINL_0757 ADINL_0757 ADINL_0741 ADINL_0741 pgk pgk ADINL_0738 ADINL_0738 dapF dapF lysA lysA ADINL_0635 ADINL_0635 fabV fabV ADINL_0631 ADINL_0631 ADINL_0626 ADINL_0626 ADINL_0610 ADINL_0610 ADINL_0565 ADINL_0565 ADINL_0564 ADINL_0564 ADINL_0563 ADINL_0563 ADINL_0562 ADINL_0562 ADINL_0558 ADINL_0558 ADINL_0524 ADINL_0524 ADINL_0523 ADINL_0523 ADINL_0522 ADINL_0522 serC serC ADINL_0489 ADINL_0489 msrP msrP ADINL_0416 ADINL_0416 hemC hemC ADINL_0406 ADINL_0406 ADINL_0405 ADINL_0405 pckA pckA cysQ cysQ rpiA rpiA ADINL_0377 ADINL_0377 ADINL_0348 ADINL_0348 ADINL_0346 ADINL_0346 glyA glyA ADINL_0329 ADINL_0329 ADINL_0328 ADINL_0328 ADINL_0321 ADINL_0321 ADINL_0320 ADINL_0320 ADINL_0264 ADINL_0264 ADINL_0263 ADINL_0263 ADINL_0254 ADINL_0254 ADINL_0223 ADINL_0223 ADINL_0211 ADINL_0211 ADINL_0140 ADINL_0140 ADINL_0134 ADINL_0134 ADINL_0118 ADINL_0118 ADINL_0102 ADINL_0102 ADINL_0099 ADINL_0099 folD folD ADINL_0048 ADINL_0048 ADINL_0024 ADINL_0024 ADINL_0022 ADINL_0022 pfkA pfkA
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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fadA3-ketoacyl-CoA thiolase Acetyl-CoA acetyltransferase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (392 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa)
cysGSiroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (462 aa)
ADINL_3126Phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. (241 aa)
ADINL_3125Oxidoreductase probably involved in sulfite reduction. (167 aa)
ADINL_3124Sulfite reductase [NADPH] hemoprotein beta-component. (552 aa)
ADINL_3123Nitrite reductase [NAD(P)H] small subunit. (126 aa)
ADINL_3122Nitrite reductase [NAD(P)H] large subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (852 aa)
ADINL_3114Assimilatory nitrate reductase large subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (881 aa)
ADINL_3113Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. (254 aa)
cysDSulfate adenylyltransferase subunit 2. (305 aa)
cysNSulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (560 aa)
rnfCElectron transport complex protein RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (565 aa)
ADINL_3094NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (450 aa)
ADINL_3080Alpha/beta hydrolase. (289 aa)
ADINL_3077Homoserine kinase. (205 aa)
ADINL_3068Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (865 aa)
accDAcetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (304 aa)
ADINL_3052Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (372 aa)
ADINL_2983Hypothetical protein. (472 aa)
ADINL_2963Dienelactone hydrolase. (314 aa)
mqoMalate:quinone oxidoreductase. (499 aa)
ADINL_2935D-3-phosphoglycerate dehydrogenase. (309 aa)
ADINL_2932Aldehyde dehydrogenase B; Belongs to the aldehyde dehydrogenase family. (497 aa)
ADINL_2897Pyridine nucleotide-disulfide oxidoreductase associated with reductive pyrimidine catabolism. (448 aa)
ADINL_2884Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family. (352 aa)
nfuANfuA Fe-S protein maturation; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (197 aa)
ADINL_2860D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (259 aa)
ADINL_28093-ketoacyl-CoA thiolase Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
gluQglutamyl-Q-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (292 aa)
ADINL_2797Rieske 2Fe-2S family protein. (105 aa)
hemLGlutamate-1-semialdehyde aminotransferase. (427 aa)
ADINL_2778Hypothetical protein. (540 aa)
thrBHomoserine kinase; Belongs to the pseudomonas-type ThrB family. (324 aa)
phnXPhosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. (273 aa)
ADINL_2729NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
ADINL_2719Putative formate dehydrogenase-specific chaperone. (304 aa)
ADINL_2718NrfD protein. (396 aa)
ADINL_2717Fe-S-cluster-containing hydrogenase components 1. (253 aa)
ADINL_2716Formate dehydrogenase O alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (826 aa)
ADINL_2696Transcriptional regulator, RpiR family. (297 aa)
ADINL_2676Demethylmenaquinone methyltransferase. (212 aa)
ADINL_2662Porphobilinogen synthase; Belongs to the ALAD family. (335 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (517 aa)
ADINL_2643Rhodanese-related sulfurtransferase; Rhodanese-like domain protein. (138 aa)
ADINL_2612Glutamate synthase [NADPH] large chain. (219 aa)
ADINL_2608Gfa-like protein. (96 aa)
ADINL_2593Zn-dependent hydrolase, including glyoxylases. (293 aa)
ADINL_2586Putative PLP-dependent aminotransferase YfdZ. (401 aa)
ADINL_2581Hypothetical protein. (110 aa)
ADINL_2574NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
ADINL_2564Lysine 2-monooxygenase. (552 aa)
ADINL_2516Isocitrate lyase. (531 aa)
ADINL_2512Low-specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (352 aa)
ADINL_2462Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (789 aa)
ADINL_2449Monomeric isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (743 aa)
ADINL_2447Oxidoreductase, aldo/keto reductase family. (345 aa)
ADINL_2423Thiosulfate sulfurtransferase, rhodanese. (281 aa)
ADINL_2391Ferredoxin--NADP(+) reductase, actinobacterial (eukaryote-like) type. (367 aa)
ADINL_2383Phosphoglucomutase. (533 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (545 aa)
ADINL_2360AAA ATPase. (298 aa)
ADINL_2340Protein acetyltransferase. (912 aa)
ADINL_2337Aspartokinase associated with ectoine biosynthesis. (475 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (128 aa)
ADINL_2335Diaminobutyrate-pyruvate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (424 aa)
ectAL-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (174 aa)
sucDSuccinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
sucCSuccinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
ADINL_2321Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. (478 aa)
ADINL_2320Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (404 aa)
ADINL_23192-oxoglutarate dehydrogenase E1 component. (963 aa)
ADINL_2318Succinate dehydrogenase iron-sulfur protein. (234 aa)
ADINL_2317Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa)
ADINL_2316Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
ADINL_2315Succinate dehydrogenase cytochrome b-556 subunit. (125 aa)
ADINL_2314Citrate synthase (si); Belongs to the citrate synthase family. (424 aa)
ADINL_2310NAD-specific glutamate dehydrogenase, large form. (1609 aa)
ADINL_22885,10-methylenetetrahydrofolate reductase. (318 aa)
ADINL_2277Hypothetical protein. (217 aa)
ADINL_2270Putative transcriptional regulator. (148 aa)
ADINL_2206Formate dehydrogenase -O, gamma subunit. (322 aa)
ADINL_2205Putative formate dehydrogenase iron-sulfur subunit. (214 aa)
ADINL_2204Formate dehydrogenase-O, major subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (953 aa)
ADINL_2202Putative formate dehydrogenase-specific chaperone. (210 aa)
ADINL_2201Iron-sulfur cluster-binding protein. (575 aa)
ADINL_2186Cytochrome c class I. (113 aa)
ADINL_2185Sulfide dehydrogenase [flavocytochrome C] flavoprotein chain precursor. (438 aa)
ADINL_2183Sulfur oxidation protein SoxZ. (252 aa)
ADINL_21023-ketoacyl-CoA thiolase Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
ADINL_2101Acetylornithine deacetylase. (423 aa)
ADINL_2027Putative lipoprotein. (317 aa)
ADINL_2025YgfY protein. (84 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (871 aa)
ADINL_20042,4-dienoyl-CoA reductase [NADPH]. (683 aa)
ADINL_2002Pyridoxamine 5'-phosphate oxidase. (198 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa)
ADINL_1996Phosphate acetyltransferase. (321 aa)
ADINL_1988Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa)
ADINL_1987Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (151 aa)
fbpFructose-1,6-bisphosphatase, type I; Belongs to the FBPase class 1 family. (323 aa)
ubiX3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (208 aa)
ADINL_1966OsmC/Ohr family protein. (133 aa)
ADINL_1958Hypothetical protein. (234 aa)
ADINL_1942Esterase ybfF. (256 aa)
ADINL_1912Glutamine synthetase type I. (468 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
bamBOuter membrane protein assembly factor BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (374 aa)
ADINL_1839Biphenyl-2,3-diol 1,2-dioxygenase III-related protein. (129 aa)
ADINL_1838Amidases related to nicotinamidase. (183 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa)
ADINL_1742Glutamate synthase [NADPH] small chain. (477 aa)
ADINL_1741Glutamate synthase [NADPH] large chain. (1484 aa)
ADINL_1740PspA. (523 aa)
ADINL_1655Ribonuclease E inhibitor RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (163 aa)
ADINL_1654Glycolate dehydrogenase, subunit GlcD. (1018 aa)
ADINL_1643Hypothetical protein. (542 aa)
folD-2Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
ADINL_1621Assimilatory nitrate reductase large subunit. (567 aa)
ADINL_1594Hypothetical protein. (66 aa)
nqrFNa(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (408 aa)
ADINL_1558NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (479 aa)
ADINL_1551Putative Acylphosphate phosphohydrolase. (96 aa)
ADINL_1549Glutamine synthetase family protein. (454 aa)
ADINL_1546Alcohol dehydrogenase. (384 aa)
ADINL_1518Phosphoglycerate mutase family. (190 aa)
ADINL_1511Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (394 aa)
ADINL_15063-hydroxyisobutyryl-CoA hydrolase. (368 aa)
ADINL_1505Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
ADINL_15013-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (378 aa)
ADINL_1495Acyl-CoA synthetases (AMP-forming)/AMP-acid ligase. (541 aa)
ADINL_1490Methylcrotonyl-CoA carboxylase biotin-containing subunit. (664 aa)
ADINL_1488Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (190 aa)
gltXGlutamyl-tRNA synthetase Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (501 aa)
ADINL_1446Threonine dehydrogenase and related Zn-dependent dehydrogenase. (399 aa)
ADINL_1405Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (501 aa)
ADINL_1400Putative protease. (444 aa)
ADINL_1348Membrane protein, distant similarity to thiosulfate:quinone oxidoreductase DoxD. (149 aa)
ADINL_1320Lactate-responsive regulator LldR in Enterobacteria, GntR family. (232 aa)
ADINL_1318Putative L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF. (472 aa)
ADINL_13154-oxalocrotonate tautomerase. (63 aa)
ADINL_13134-oxalocrotonate decarboxylase. (263 aa)
ADINL_13124-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (345 aa)
ADINL_1311Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (303 aa)
ADINL_13104-oxalocrotonate decarboxylase. (261 aa)
ADINL_1308Catechol 2,3-dioxygenase. (307 aa)
ADINL_1306Phenol hydroxylase, FAD- and [2Fe-2S]-containing reductase component DmpP. (353 aa)
ADINL_1305Phenol hydroxylase, P4 oxygenase component DmpO. (120 aa)
ADINL_1304Phenol hydroxylase, P3 oxygenase component DmpN. (500 aa)
ADINL_1303Phenol hydroxylase, P2 regulatory component DmpM. (89 aa)
ADINL_1302Phenol hydroxylase, P1 oxygenase component DmpL. (328 aa)
ADINL_1301Phenol hydroxylase, assembly protein DmpK. (102 aa)
ADINL_1300Putative deacylase. (347 aa)
ADINL_1274Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (295 aa)
ADINL_1273Oxygen-insensitive NADPH nitroreductase; Belongs to the flavin oxidoreductase frp family. (246 aa)
ADINL_1272Putative flavoprotein YqcA (clustered with tRNA pseudouridine synthase C). (148 aa)
ADINL_1268Exopolyphosphatase-related protein. (309 aa)
ADINL_1263Hypothetical protein. (145 aa)
ADINL_1256Acetoacetyl-CoA synthetase. (649 aa)
glpEThiosulfate sulfurtransferase GlpE; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. (105 aa)
ADINL_1225Hypothetical protein. (492 aa)
ADINL_1223Alcohol dehydrogenase. (382 aa)
ADINL_1222D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
ADINL_1212Glutamate synthase [NADPH] large chain; Belongs to the glutamate synthase family. (441 aa)
ADINL_1211Glutamate synthase [NADPH] putative GlxC chain. (227 aa)
ADINL_1210Glutamine amidotransferase protein GlxB. (301 aa)
ADINL_1209Glutamine synthetase type I. (444 aa)
ADINL_1202Putative protease. (302 aa)
ADINL_1201Putative protease. (331 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (366 aa)
ADINL_1180Probably aromatic ring hydroxylating enzyme, evidenced byr; PaaD-like protein (DUF59) involved in Fe-S cluster assembly. (177 aa)
ADINL_1172Serine acetyltransferase. (258 aa)
queGEpoxyqueuosine (oQ) reductase QueG; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (378 aa)
ADINL_1146Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (174 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (217 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (457 aa)
ADINL_1129N-succinyl-L,L-diaminopimelate aminotransferase alternative. (398 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (343 aa)
dapEN-succinyl-L,L-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (379 aa)
ADINL_1106Oxaloacetate decarboxylase beta chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family. (433 aa)
ADINL_1102Aspartokinase; Belongs to the aspartokinase family. (411 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (431 aa)
accAAcetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa)
ADINL_1047Ribosomal-protein-L7p-serine acetyltransferase. (183 aa)
ADINL_1014Enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (716 aa)
ADINL_10023-ketoacyl-CoA thiolase Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (425 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (334 aa)
ADINL_0987Phosphoserine phosphatase. (401 aa)
ADINL_0978Succinate-semialdehyde dehydrogenase [NAD(P)+]. (456 aa)
ADINL_0977Diaminobutyrate-pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (424 aa)
ADINL_0953Putative Lipoprotein. (297 aa)
ADINL_0939Isopropylmalate/homocitrate/citramalate synthase. (140 aa)
ADINL_0922Threonine synthase. (464 aa)
ADINL_0921Homoserine dehydrogenase. (433 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (269 aa)
ADINL_0862NADP-dependent malic enzyme. (421 aa)
ADINL_0843Fumarylacetoacetate hydrolase family protein. (219 aa)
ADINL_0837D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (407 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa)
ureAUrease gamma subunit; Belongs to the urease gamma subunit family. (100 aa)
ureBUrease beta subunit; Belongs to the urease beta subunit family. (101 aa)
ureCUrease alpha subunit. (567 aa)
ADINL_0793NADH-dependent flavin oxidoreductase. (366 aa)
ADINL_0784Hydantoin racemase. (243 aa)
ADINL_0777Uricase (urate oxidase). (308 aa)
alcAllantoicase; Belongs to the allantoicase family. (334 aa)
ADINL_0774Putative rpiR-family transcriptional regulatory protein. (282 aa)
ADINL_0769Membrane-bound lytic murein transglycosylase B precursor. (434 aa)
srkAYihE protein, required for LPS synthesis; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (329 aa)
ADINL_0760Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A. (488 aa)
ADINL_0759Xanthine dehydrogenase, molybdenum binding subunit. (780 aa)
ADINL_07572-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase. (284 aa)
ADINL_0741Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (389 aa)
ADINL_0738Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (276 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (418 aa)
ADINL_06353-hydroxyisobutyryl-CoA hydrolase. (366 aa)
fabVShort-chain alcohol dehydrogenase family; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (398 aa)
ADINL_06313-hydroxybutyryl-CoA dehydratase. (143 aa)
ADINL_0626Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (222 aa)
ADINL_0610D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
ADINL_0565Glycolate utilization operon transcriptional activator GlcC. (251 aa)
ADINL_0564Glycolate dehydrogenase, subunit GlcD. (499 aa)
ADINL_0563Glycolate dehydrogenase, FAD-binding subunit GlcE. (365 aa)
ADINL_0562Glycolate dehydrogenase, iron-sulfur subunit GlcF. (406 aa)
ADINL_0558Putative carboxypeptidase. (192 aa)
ADINL_0524Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (656 aa)
ADINL_0523Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (878 aa)
ADINL_0522Lactate-responsive regulator LldR in Enterobacteria, GntR family. (263 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (360 aa)
ADINL_0489Alcohol dehydrogenase. (346 aa)
msrPPutative sulfite oxidase subunit YedY; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce [...] (335 aa)
ADINL_0416Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family. (439 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (337 aa)
ADINL_0406Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (273 aa)
ADINL_0405HemX like protein. (326 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (515 aa)
cysQ3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (272 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (225 aa)
ADINL_0377Pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
ADINL_0348S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (253 aa)
ADINL_0346S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (372 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa)
ADINL_0329Tungsten-containing formate dehydrogenase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (928 aa)
ADINL_0328Tungsten-containing formate dehydrogenase beta subunit. (548 aa)
ADINL_0321Putative L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF. (639 aa)
ADINL_0320DgcA Dimethylglycine demethylase subunit A. (689 aa)
ADINL_0264Succinate-semialdehyde dehydrogenase [NAD(P)+]; Belongs to the aldehyde dehydrogenase family. (484 aa)
ADINL_0263Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (424 aa)
ADINL_0254Transcriptional regulator, GntR family. (252 aa)
ADINL_0223Spore coat polysaccharide biosynthesis protein spsF. (539 aa)
ADINL_0211Hypothetical protein. (375 aa)
ADINL_0140Cation/multidrug efflux pump. (185 aa)
ADINL_0134L-2-hydroxyglutarate oxidase. (398 aa)
ADINL_0118Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
ADINL_0102Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; Vanillate O-demethylase oxidoreductase. (315 aa)
ADINL_0099Small molecule metabolism. (454 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (295 aa)
ADINL_0048Gfa-like protein. (59 aa)
ADINL_0024Glutamine synthetase family protein. (454 aa)
ADINL_0022Glutamine synthetase family protein. (448 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (334 aa)
Your Current Organism:
Nitrincola lacisaponensis
NCBI taxonomy Id: 267850
Other names: ATCC BAA-920, DSM 16316, N. lacisaponensis, Nitrincola lacisaponensis Dimitriu et al. 2005, strain 4CA
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