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thiE thiE cysE cysE menD menD acd2 acd2 oxdhA2 oxdhA2 cofG cofG metE1 metE1 metE2 metE2 thiL thiL thiDN thiDN thi4 thi4 korB3 korB3 acs3 acs3 acs4 acs4 Nmlp_3628 Nmlp_3628 korB1 korB1 korA korA asd asd porA porA porB porB ilvB ilvB cysK cysK acd3 acd3 acs1 acs1 korB2 korB2 folD folD Nmlp_2984 Nmlp_2984 thrC3 thrC3 Nmlp_2816 Nmlp_2816 oxdhB oxdhB oxdhA1 oxdhA1 mat mat metY1 metY1 metX metX lipA lipA metY2 metY2 Nmlp_1431 Nmlp_1431 cynT cynT mtaD mtaD acd1 acd1 Tif2Bd Tif2Bd thrC1 thrC1 thiM thiM
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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thiEThiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (214 aa)
cysESerine O-acetyltransferase; Gene has a frameshift and is truncated at both termini; locus_tag: Nmlp_1987; product: DNA N-glycosylase (nonfunctional). (188 aa)
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (586 aa)
acd2acyl-CoA dehydrogenase. (384 aa)
oxdhA2Probable 2-oxoacid dehydrogenase E1 component alpha subunit. (372 aa)
cofG7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (358 aa)
metE15-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (methionine synthase II). (356 aa)
metE25-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (methionine synthase II). (326 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (290 aa)
thiDNPhosphomethylpyrimidine kinase / phosphomethylpyrimidine phosphate kinase / thiamine-phosphate synthase. (412 aa)
thi4Thiamine thiazole synthase; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (309 aa)
korB3Oxoglutarate--ferredoxin oxidoreductase beta subunit. (287 aa)
acs3acyl-CoA synthetase. (663 aa)
acs4acyl-CoA synthetase. (654 aa)
Nmlp_3628Metal dependent hydrolase family protein. (471 aa)
korB1Oxoglutarate--ferredoxin oxidoreductase beta subunit. (289 aa)
korAOxoglutarate--ferredoxin oxidoreductase alpha subunit. (587 aa)
asdAspartate-semialdehyde dehydrogenase. (344 aa)
porAPyruvate--ferredoxin oxidoreductase alpha subunit. (628 aa)
porBPyruvate--ferredoxin oxidoreductase beta subunit. (312 aa)
ilvBAcetolactate synthase large subunit. (580 aa)
cysKCysteine synthase. (329 aa)
acd3acyl-CoA dehydrogenase. (373 aa)
acs1acyl-CoA synthetase. (672 aa)
korB2Oxoglutarate--ferredoxin oxidoreductase beta subunit. (289 aa)
folDMethylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (297 aa)
Nmlp_2984Homolog to sulfate adenylyltransferase small subunit. (322 aa)
thrC3Threonine synthase. (391 aa)
Nmlp_2816DRTGG domain protein. (352 aa)
oxdhB2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit. (329 aa)
oxdhA12-oxo-3-methylvalerate dehydrogenase E1 component alpha subunit. (373 aa)
matS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (401 aa)
metY1O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase). (425 aa)
metXHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (401 aa)
lipALipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (312 aa)
metY2O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase). (429 aa)
Nmlp_1431Rhodanese domain protein. (119 aa)
cynTCarbonic anhydrase. (231 aa)
mtaD5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (432 aa)
acd1acyl-CoA dehydrogenase. (380 aa)
Tif2BdeIF-2B domain protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (284 aa)
thrC1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (436 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (275 aa)
Your Current Organism:
Natronomonas moolapensis
NCBI taxonomy Id: 268739
Other names: N. moolapensis 8.8.11, Natronomonas moolapensis 8.8.11, Natronomonas moolapensis DSM 18674, Natronomonas moolapensis JCM 14361, Natronomonas moolapensis str. 8.8.11, Natronomonas moolapensis strain 8.8.11, haloarchaeon CSW8.8.11
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