(30 nodes) Glyoxylate and dicarboxylate metabolism network (Natronomonas moolapensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Nmlp_1402	HAD superfamily hydrolase. (208 aa)
	Nmlp_1665	DUF4147 domain protein. (433 aa)
	purU	Formyltetrahydrofolate deformylase. (319 aa)
	Nmlp_1924	HAD superfamily hydrolase. (217 aa)
	mmcB	methylmalonyl-CoA mutase subunit B (cobalamin-binding subunit). (138 aa)
	mce	methylmalonyl-CoA epimerase. (127 aa)
	mmcA2	methylmalonyl-CoA mutase subunit A. (556 aa)
	lpdA1	Dihydrolipoyl dehydrogenase. (474 aa)
	Nmlp_2297	Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (226 aa)
	aceA	Isocitrate lyase. (355 aa)
	aceB	Malate synthase. (436 aa)
	acaB1	acetyl-CoA C-acetyltransferase catalytic subunit. (384 aa)
	gltB	Glutamate synthase large subunit. (1507 aa)
	gcvH	Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
	glyA	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
	acaB3	acetyl-CoA C-acyltransferase. (392 aa)
	acs1	acyl-CoA synthetase. (672 aa)
	mmcA1	methylmalonyl-CoA mutase subunit A. (565 aa)
	citZ	Citrate synthase. (378 aa)
	pccB	propionyl-CoA carboxylase carboxyltransferase component. (516 aa)
	pccX	propionyl-CoA carboxylase small subunit. (83 aa)
	pccA	propionyl-CoA carboxylase biotin carboxylase component. (614 aa)
	acaB2	acetyl-CoA C-acetyltransferase. (388 aa)
	gcvT	Homolog to glycine cleavage system protein T. (360 aa)
	acs4	acyl-CoA synthetase. (654 aa)
	acs3	acyl-CoA synthetase. (663 aa)
	citB	Aconitate hydratase. (661 aa)
	glnA	Glutamine synthetase. (456 aa)
	phaJ	(R)-specific enoyl-CoA hydratase. (215 aa)
	mdh	Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (303 aa)

Your Current Organism:

Natronomonas moolapensis

NCBI taxonomy Id: 268739
Other names: N. moolapensis 8.8.11, Natronomonas moolapensis 8.8.11, Natronomonas moolapensis DSM 18674, Natronomonas moolapensis JCM 14361, Natronomonas moolapensis str. 8.8.11, Natronomonas moolapensis strain 8.8.11, haloarchaeon CSW8.8.11

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Nmlp_1402	Nmlp_1924	Nmlp_1402	Nmlp_1924	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.924
Nmlp_1402	Nmlp_2297	Nmlp_1402	Nmlp_2297	HAD superfamily hydrolase.	Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.	0.905
Nmlp_1665	glyA	Nmlp_1665	Nmlp_3079	DUF4147 domain protein.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.475
Nmlp_1924	Nmlp_1402	Nmlp_1924	Nmlp_1402	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.924
Nmlp_1924	Nmlp_2297	Nmlp_1924	Nmlp_2297	HAD superfamily hydrolase.	Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.	0.921
Nmlp_2297	Nmlp_1402	Nmlp_2297	Nmlp_1402	Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.	HAD superfamily hydrolase.	0.905
Nmlp_2297	Nmlp_1924	Nmlp_2297	Nmlp_1924	Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.	HAD superfamily hydrolase.	0.921
acaB1	acaB2	Nmlp_2716	Nmlp_3314	acetyl-CoA C-acetyltransferase catalytic subunit.	acetyl-CoA C-acetyltransferase.	0.908
acaB1	acaB3	Nmlp_2716	Nmlp_3125	acetyl-CoA C-acetyltransferase catalytic subunit.	acetyl-CoA C-acyltransferase.	0.911
acaB1	acs1	Nmlp_2716	Nmlp_3127	acetyl-CoA C-acetyltransferase catalytic subunit.	acyl-CoA synthetase.	0.948
acaB1	acs3	Nmlp_2716	Nmlp_3687	acetyl-CoA C-acetyltransferase catalytic subunit.	acyl-CoA synthetase.	0.949
acaB1	acs4	Nmlp_2716	Nmlp_3685	acetyl-CoA C-acetyltransferase catalytic subunit.	acyl-CoA synthetase.	0.949
acaB1	citZ	Nmlp_2716	Nmlp_3251	acetyl-CoA C-acetyltransferase catalytic subunit.	Citrate synthase.	0.945
acaB1	mce	Nmlp_2716	Nmlp_2070	acetyl-CoA C-acetyltransferase catalytic subunit.	methylmalonyl-CoA epimerase.	0.561
acaB1	pccA	Nmlp_2716	Nmlp_3309	acetyl-CoA C-acetyltransferase catalytic subunit.	propionyl-CoA carboxylase biotin carboxylase component.	0.936
acaB1	pccB	Nmlp_2716	Nmlp_3307	acetyl-CoA C-acetyltransferase catalytic subunit.	propionyl-CoA carboxylase carboxyltransferase component.	0.947
acaB1	pccX	Nmlp_2716	Nmlp_3308	acetyl-CoA C-acetyltransferase catalytic subunit.	propionyl-CoA carboxylase small subunit.	0.900
acaB1	phaJ	Nmlp_2716	Nmlp_3929	acetyl-CoA C-acetyltransferase catalytic subunit.	(R)-specific enoyl-CoA hydratase.	0.539
acaB2	acaB1	Nmlp_3314	Nmlp_2716	acetyl-CoA C-acetyltransferase.	acetyl-CoA C-acetyltransferase catalytic subunit.	0.908
acaB2	acaB3	Nmlp_3314	Nmlp_3125	acetyl-CoA C-acetyltransferase.	acetyl-CoA C-acyltransferase.	0.911

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