(22 nodes) Propanoate metabolism network (Natronomonas moolapensis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	mgsA	Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (127 aa)
	Nmlp_1469	PrpD family protein. (416 aa)
	mmcB	methylmalonyl-CoA mutase subunit B (cobalamin-binding subunit). (138 aa)
	mce	methylmalonyl-CoA epimerase. (127 aa)
	mmcA2	methylmalonyl-CoA mutase subunit A. (556 aa)
	mmsA	Methylmalonate-semialdehyde dehydrogenase. (493 aa)
	lpdA1	Dihydrolipoyl dehydrogenase. (474 aa)
	acaB1	acetyl-CoA C-acetyltransferase catalytic subunit. (384 aa)
	acdA	acetate--CoA ligase (ADP-forming). (697 aa)
	acaB3	acetyl-CoA C-acyltransferase. (392 aa)
	acs1	acyl-CoA synthetase. (672 aa)
	mmcA1	methylmalonyl-CoA mutase subunit A. (565 aa)
	porB	Pyruvate--ferredoxin oxidoreductase beta subunit. (312 aa)
	porA	Pyruvate--ferredoxin oxidoreductase alpha subunit. (628 aa)
	sucD	succinate--CoA ligase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa)
	sucC	succinate--CoA ligase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (382 aa)
	pccB	propionyl-CoA carboxylase carboxyltransferase component. (516 aa)
	pccX	propionyl-CoA carboxylase small subunit. (83 aa)
	pccA	propionyl-CoA carboxylase biotin carboxylase component. (614 aa)
	acaB2	acetyl-CoA C-acetyltransferase. (388 aa)
	acs4	acyl-CoA synthetase. (654 aa)
	acs3	acyl-CoA synthetase. (663 aa)

Your Current Organism:

Natronomonas moolapensis

NCBI taxonomy Id: 268739
Other names: N. moolapensis 8.8.11, Natronomonas moolapensis 8.8.11, Natronomonas moolapensis DSM 18674, Natronomonas moolapensis JCM 14361, Natronomonas moolapensis str. 8.8.11, Natronomonas moolapensis strain 8.8.11, haloarchaeon CSW8.8.11

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Nmlp_1469	acs1	Nmlp_1469	Nmlp_3127	PrpD family protein.	acyl-CoA synthetase.	0.415
Nmlp_1469	pccB	Nmlp_1469	Nmlp_3307	PrpD family protein.	propionyl-CoA carboxylase carboxyltransferase component.	0.520
acaB1	acaB2	Nmlp_2716	Nmlp_3314	acetyl-CoA C-acetyltransferase catalytic subunit.	acetyl-CoA C-acetyltransferase.	0.908
acaB1	acaB3	Nmlp_2716	Nmlp_3125	acetyl-CoA C-acetyltransferase catalytic subunit.	acetyl-CoA C-acyltransferase.	0.911
acaB1	acdA	Nmlp_2716	Nmlp_2817	acetyl-CoA C-acetyltransferase catalytic subunit.	acetate--CoA ligase (ADP-forming).	0.955
acaB1	acs1	Nmlp_2716	Nmlp_3127	acetyl-CoA C-acetyltransferase catalytic subunit.	acyl-CoA synthetase.	0.948
acaB1	acs3	Nmlp_2716	Nmlp_3687	acetyl-CoA C-acetyltransferase catalytic subunit.	acyl-CoA synthetase.	0.949
acaB1	acs4	Nmlp_2716	Nmlp_3685	acetyl-CoA C-acetyltransferase catalytic subunit.	acyl-CoA synthetase.	0.949
acaB1	mce	Nmlp_2716	Nmlp_2070	acetyl-CoA C-acetyltransferase catalytic subunit.	methylmalonyl-CoA epimerase.	0.561
acaB1	mmsA	Nmlp_2716	Nmlp_2084	acetyl-CoA C-acetyltransferase catalytic subunit.	Methylmalonate-semialdehyde dehydrogenase.	0.918
acaB1	pccA	Nmlp_2716	Nmlp_3309	acetyl-CoA C-acetyltransferase catalytic subunit.	propionyl-CoA carboxylase biotin carboxylase component.	0.936
acaB1	pccB	Nmlp_2716	Nmlp_3307	acetyl-CoA C-acetyltransferase catalytic subunit.	propionyl-CoA carboxylase carboxyltransferase component.	0.947
acaB1	pccX	Nmlp_2716	Nmlp_3308	acetyl-CoA C-acetyltransferase catalytic subunit.	propionyl-CoA carboxylase small subunit.	0.900
acaB1	porA	Nmlp_2716	Nmlp_3265	acetyl-CoA C-acetyltransferase catalytic subunit.	Pyruvate--ferredoxin oxidoreductase alpha subunit.	0.907
acaB1	porB	Nmlp_2716	Nmlp_3264	acetyl-CoA C-acetyltransferase catalytic subunit.	Pyruvate--ferredoxin oxidoreductase beta subunit.	0.902
acaB1	sucC	Nmlp_2716	Nmlp_3305	acetyl-CoA C-acetyltransferase catalytic subunit.	succinate--CoA ligase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.850
acaB1	sucD	Nmlp_2716	Nmlp_3304	acetyl-CoA C-acetyltransferase catalytic subunit.	succinate--CoA ligase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.862
acaB2	acaB1	Nmlp_3314	Nmlp_2716	acetyl-CoA C-acetyltransferase.	acetyl-CoA C-acetyltransferase catalytic subunit.	0.908
acaB2	acaB3	Nmlp_3314	Nmlp_3125	acetyl-CoA C-acetyltransferase.	acetyl-CoA C-acyltransferase.	0.911
acaB2	acdA	Nmlp_3314	Nmlp_2817	acetyl-CoA C-acetyltransferase.	acetate--CoA ligase (ADP-forming).	0.958

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