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secA secA Rru_A0497 Rru_A0497 Rru_A0498 Rru_A0498 Rru_A0499 Rru_A0499 Rru_A0500 Rru_A0500 Rru_A0563 Rru_A0563 Rru_A0584 Rru_A0584 Rru_A0585 Rru_A0585 Rru_A0588 Rru_A0588 Rru_A0589 Rru_A0589 Rru_A0590 Rru_A0590 Rru_A0591 Rru_A0591 Rru_A0592 Rru_A0592 Rru_A0683 Rru_A0683 Rru_A0799 Rru_A0799 Rru_A0800 Rru_A0800 Rru_A0801 Rru_A0801 Rru_A0802 Rru_A0802 Rru_A0803 Rru_A0803 Rru_A0805 Rru_A0805 Rru_A0806 Rru_A0806 Rru_A0807 Rru_A0807 Rru_A0808 Rru_A0808 Rru_A0979 Rru_A0979 Rru_A0980 Rru_A0980 Rru_A0981 Rru_A0981 Rru_A0982 Rru_A0982 Rru_A1159 Rru_A1159 ftsY ftsY ffh ffh Rru_A1312 Rru_A1312 hfq hfq Rru_A1746 Rru_A1746 Rru_A1748 Rru_A1748 Rru_A1749 Rru_A1749 Rru_A1750 Rru_A1750 Rru_A1751 Rru_A1751 yajC yajC Rru_A1825 Rru_A1825 Rru_A1888 Rru_A1888 trpE trpE Rru_A1895 Rru_A1895 Rru_A1911 Rru_A1911 Rru_A1917 Rru_A1917 Rru_A1918 Rru_A1918 Rru_A1919 Rru_A1919 Rru_A1920 Rru_A1920 Rru_A1921 Rru_A1921 Rru_A2011 Rru_A2011 Rru_A2012 Rru_A2012 Rru_A2013 Rru_A2013 Rru_A2014 Rru_A2014 Rru_A2045 Rru_A2045 Rru_A2046 Rru_A2046 Rru_A2047 Rru_A2047 potA-2 potA-2 Rru_A2052 Rru_A2052 Rru_A2101 Rru_A2101 Rru_A2174 Rru_A2174 Rru_A2175 Rru_A2175 Rru_A2176 Rru_A2176 Rru_A2177 Rru_A2177 Rru_A2178 Rru_A2178 Rru_A2191 Rru_A2191 Rru_A2474 Rru_A2474 secY secY secE secE Rru_A2873 Rru_A2873 Rru_A3303 Rru_A3303 Rru_A3304 Rru_A3304 Rru_A3305 Rru_A3305 Rru_A3306 Rru_A3306 Rru_A3307 Rru_A3307 yidC yidC Rru_A3395 Rru_A3395 Rru_A3396 Rru_A3396 Rru_A3413 Rru_A3413 Rru_A3414 Rru_A3414 Rru_A3415 Rru_A3415 Rru_A3416 Rru_A3416 Rru_A3417 Rru_A3417 Rru_A3505 Rru_A3505 Rru_A3506 Rru_A3506 Rru_A3507 Rru_A3507 Rru_A3508 Rru_A3508 Rru_A3509 Rru_A3509 Rru_A3510 Rru_A3510 secB secB ribA ribA Rru_A3664 Rru_A3664 secF-2 secF-2 Rru_A3724 Rru_A3724 Rru_A3725 Rru_A3725 Rru_A3726 Rru_A3726 Rru_A3727 Rru_A3727 Rru_A3728 Rru_A3728
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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secAProtein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (931 aa)
Rru_A0497ABC transporter component; Belongs to the ABC transporter superfamily. (366 aa)
Rru_A0498Binding-protein-dependent transport systems inner membrane component. (260 aa)
Rru_A0499Binding-protein-dependent transport systems inner membrane component. (290 aa)
Rru_A0500Extracellular solute-binding protein, family 1. (367 aa)
Rru_A0563Twin-arginine translocation pathway signal. (421 aa)
Rru_A0584Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (613 aa)
Rru_A0585ABC transporter component. (259 aa)
Rru_A0588Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like; Belongs to the ABC transporter superfamily. (338 aa)
Rru_A0589Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like; Belongs to the ABC transporter superfamily. (330 aa)
Rru_A0590Binding-protein-dependent transport systems inner membrane component. (302 aa)
Rru_A0591Binding-protein-dependent transport systems inner membrane component. (308 aa)
Rru_A0592Extracellular solute-binding protein, family 5. (545 aa)
Rru_A06833-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (461 aa)
Rru_A0799Extracellular solute-binding protein, family 5. (531 aa)
Rru_A0800Binding-protein-dependent transport systems inner membrane component. (356 aa)
Rru_A0801Binding-protein-dependent transport systems inner membrane component. (296 aa)
Rru_A0802ABC transporter component. (276 aa)
Rru_A0803ABC transporter component. (252 aa)
Rru_A0805Conjugal transfer protein. (258 aa)
Rru_A0806Conjugal transfer protein. (89 aa)
Rru_A0807Conjugal transfer protein TrbC. (110 aa)
Rru_A0808Type II secretion system protein E. (326 aa)
Rru_A0979Extracellular solute-binding protein, family 5. (530 aa)
Rru_A0980Binding-protein-dependent transport systems inner membrane component. (313 aa)
Rru_A0981Binding-protein-dependent transport systems inner membrane component. (314 aa)
Rru_A0982ABC transporter component; Belongs to the ABC transporter superfamily. (541 aa)
Rru_A1159Two component transcriptional regulator, winged helix family. (230 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (506 aa)
ffhSignal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] (504 aa)
Rru_A1312AMP-dependent synthetase and ligase. (564 aa)
hfqRNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (83 aa)
Rru_A1746Extracellular ligand-binding receptor. (368 aa)
Rru_A1748ABC transporter component. (240 aa)
Rru_A1749ABC transporter component. (314 aa)
Rru_A1750Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (452 aa)
Rru_A1751Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (304 aa)
yajCProtein translocase subunit yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (143 aa)
Rru_A1825Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa)
Rru_A1888Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (146 aa)
trpEAnthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (504 aa)
Rru_A1895Anthranilate synthase, component II. (196 aa)
Rru_A1911Ferric uptake regulator (FUR) family; Belongs to the Fur family. (177 aa)
Rru_A1917Extracellular solute-binding protein, family 5. (518 aa)
Rru_A1918Binding-protein-dependent transport systems inner membrane component. (333 aa)
Rru_A1919Binding-protein-dependent transport systems inner membrane component. (310 aa)
Rru_A1920ABC transporter component. (276 aa)
Rru_A1921ABC transporter component. (262 aa)
Rru_A2011ABC transporter component; Belongs to the ABC transporter superfamily. (560 aa)
Rru_A2012Binding-protein-dependent transport systems inner membrane component. (276 aa)
Rru_A2013Binding-protein-dependent transport systems inner membrane component. (326 aa)
Rru_A2014Twin-arginine translocation pathway signal. (534 aa)
Rru_A2045Binding-protein-dependent transport systems inner membrane component. (275 aa)
Rru_A2046Binding-protein-dependent transport systems inner membrane component. (406 aa)
Rru_A2047Extracellular solute-binding protein, family 1. (350 aa)
potA-2ABC transporter component; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (363 aa)
Rru_A2052RND efflux system, outer membrane lipoprotein, NodT. (499 aa)
Rru_A2101Two component, sigma54 specific, transcriptional regulator, Fis family. (478 aa)
Rru_A2174Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like; Belongs to the ABC transporter superfamily. (326 aa)
Rru_A2175Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like; Belongs to the ABC transporter superfamily. (344 aa)
Rru_A2176Binding-protein-dependent transport systems inner membrane component. (324 aa)
Rru_A2177Binding-protein-dependent transport systems inner membrane component. (363 aa)
Rru_A2178Extracellular solute-binding protein, family 5. (561 aa)
Rru_A2191AMP-dependent synthetase and ligase. (605 aa)
Rru_A2474Extracellular solute-binding protein, family 5. (525 aa)
secYProtein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (447 aa)
secEProtein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (65 aa)
Rru_A2873Extracellular ligand-binding receptor. (394 aa)
Rru_A3303Amide-urea binding protein. (404 aa)
Rru_A3304ABC transporter component. (250 aa)
Rru_A3305ABC transporter component. (242 aa)
Rru_A3306Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (295 aa)
Rru_A3307Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (314 aa)
yidCProtein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (595 aa)
Rru_A3395Transcriptional regulator, LuxR family. (260 aa)
Rru_A3396Autoinducer synthesis protein. (206 aa)
Rru_A3413ABC transporter component. (233 aa)
Rru_A3414ABC transporter component. (255 aa)
Rru_A3415Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (295 aa)
Rru_A3416Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (290 aa)
Rru_A3417Extracellular ligand-binding receptor. (409 aa)
Rru_A3505ABC transporter component. (281 aa)
Rru_A3506Putative branched-chain amino acid transport system substrate-binding protein. (408 aa)
Rru_A3507Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (373 aa)
Rru_A3508Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (297 aa)
Rru_A3509AMP-dependent synthetase and ligase. (655 aa)
Rru_A3510ABC transporter component. (274 aa)
secBProtein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (160 aa)
ribAGTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (384 aa)
Rru_A3664ABC transporter component. (230 aa)
secF-2Protein translocase subunit secD / protein translocase subunit secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (853 aa)
Rru_A3724ABC transporter component. (260 aa)
Rru_A3725ABC transporter component. (246 aa)
Rru_A3726Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (300 aa)
Rru_A3727Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (334 aa)
Rru_A3728Extracellular ligand-binding receptor. (392 aa)
Your Current Organism:
Rhodospirillum rubrum
NCBI taxonomy Id: 269796
Other names: R. rubrum ATCC 11170, Rhodospirillum rubrum ATCC 11170, Rhodospirillum rubrum S1, Rhodospirillum rubrum str. ATCC 11170, Rhodospirillum rubrum strain ATCC 11170
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