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| | gatD | Asparaginase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (424 aa) |
| | AAZ69027.1 | dTDP-glucose 4,6-dehydratase. (316 aa) |
| | rpoD | DNA-directed RNA polymerase, subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (266 aa) |
| | rps11 | SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (126 aa) |
| | rps4 | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (216 aa) |
| | rps13 | SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (162 aa) |
| | truB | tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (338 aa) |
| | cmk | Cytidylate kinase. (180 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa) |
| | secY | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (492 aa) |
| | rpl15 | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (140 aa) |
| | rpl30 | LSU ribosomal protein L30P. (153 aa) |
| | rps5 | SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (208 aa) |
| | rpl18 | LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (174 aa) |
| | rpl19e | LSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (150 aa) |
| | rpl32e | LSU ribosomal protein L32E; Belongs to the eukaryotic ribosomal protein eL32 family. (145 aa) |
| | rpl6 | LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rps8 | SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rps14 | SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (50 aa) |
| | rpl5 | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (169 aa) |
| | rps4e | SSU ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (235 aa) |
| | rpl24 | LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (116 aa) |
| | rpl14 | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa) |
| | rps17 | SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (109 aa) |
| | rpl29 | LSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (67 aa) |
| | rps3 | SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (311 aa) |
| | rpl22 | LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (151 aa) |
| | rps19 | SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa) |
| | rpl2 | LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa) |
| | rpl23 | LSU ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (82 aa) |
| | rpl4 | LSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (253 aa) |
| | rpl3 | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (337 aa) |
| | AAZ69130.1 | ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (579 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa) |
| | tfe | Transcription factor IIE (TFIIE), alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...] (164 aa) |
| | AAZ69182.1 | Conserved hypothetical protein. (354 aa) |
| | AAZ69242.1 | Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (182 aa) |
| | AAZ69251.1 | Long-chain fatty-acid-CoA ligase. (492 aa) |
| | AAZ69263.1 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase fami [...] (545 aa) |
| | rps27ae | SSU ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. (49 aa) |
| | rps24e | SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (101 aa) |
| | AAZ69269.1 | DNA-directed RNA polymerase, subunit E'. (194 aa) |
| | AAZ69270.1 | SSU processome protein Utp24. (122 aa) |
| | eif2g | Translation initiation factor 2 subunit gamma (aeIF-2g); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (426 aa) |
| | prf1 | Peptide chain release factor subunit 1 (aeRF-1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (415 aa) |
| | rps19e | SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (149 aa) |
| | AAZ69437.1 | DNA-binding TFAR19-related protein; Belongs to the PDCD5 family. (122 aa) |
| | AAZ69438.1 | Conserved hypothetical ATP-binding protein. (205 aa) |
| | rpl39e | LSU ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | rpl31e | LSU ribosomal protein L31E; Belongs to the ribosomal protein L31e family. (89 aa) |
| | eif6 | Translation initiation factor 6 (aeIF-6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (219 aa) |
| | rpl18a | LSU ribosomal protein LX. (62 aa) |
| | AAZ69515.1 | Translation initiation factor 1 (eIF-1/SUI1); Belongs to the SUI1 family. (102 aa) |
| | serS1 | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily. (450 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (710 aa) |
| | tbp | TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (183 aa) |
| | rpl12 | LSU ribosomal protein L12AE; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (106 aa) |
| | rpl10 | LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (346 aa) |
| | rpl1 | LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (213 aa) |
| | rpl11 | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (161 aa) |
| | secE | Protein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (71 aa) |
| | AAZ69601.1 | Transcriptional regulator, XRE family. (161 aa) |
| | rpl40e | LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa) |
| | eif5a | Translation initiation factor 5A precursor (eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (128 aa) |
| | AAZ69770.1 | Ribose 1,5-bisphosphate isomerase; Belongs to the eIF-2B alpha/beta/delta subunits family. (307 aa) |
| | flpA | rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (226 aa) |
| | AAZ69782.1 | rRNA biogenesis protein Nop56/Nop58. (336 aa) |
| | AAZ69852.1 | DNA-directed RNA polymerase, subunit M; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (104 aa) |
| | gatC | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (93 aa) |
| | gatA | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (475 aa) |
| | gatB | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (495 aa) |
| | AAZ69919.1 | Conserved hypothetical protein. (1051 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (517 aa) |
| | AAZ69943.1 | Translation elongation factor. (356 aa) |
| | prf1-2 | Peptide chain release factor subunit 1 (aeRF-1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (415 aa) |
| | argS | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (569 aa) |
| | tbp-2 | TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (184 aa) |
| | AAZ70041.1 | GTP-binding conserved hypothetical protein TIGR00650. (394 aa) |
| | rps17e | SSU ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (64 aa) |
| | sepS | phosphoserine-tRNA(Cys) ligase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (539 aa) |
| | AAZ70176.1 | glycyl-tRNA synthetase. (607 aa) |
| | map | Methionine aminopeptidase, type II; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (296 aa) |
| | rpl10e | LSU ribosomal protein L10AE; Belongs to the universal ribosomal protein uL16 family. (173 aa) |
| | eif2b | Translation initiation factor 2 subunit beta (aeIF-2b); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (202 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (473 aa) |
| | pheS | phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (492 aa) |
| | AAZ70337.1 | DNA helicase RepD. (773 aa) |
| | tfb | Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (337 aa) |
| | AAZ70355.1 | snoRNP protein GAR1. (86 aa) |
| | rps2 | SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (247 aa) |
| | rpoK | DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa) |
| | rpoN | DNA-directed RNA polymerase, subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (62 aa) |
| | rps9 | SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (134 aa) |
| | rpl13 | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (140 aa) |
| | rpl18e | LSU ribosomal protein L18AE; Belongs to the eukaryotic ribosomal protein eL18 family. (139 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (571 aa) |
| | nop10 | Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (51 aa) |
| | AAZ70514.1 | Translation initiation factor 2 subunit alpha (aeIF-2a). (268 aa) |
| | rps27e | SSU ribosomal protein S27E. (62 aa) |
| | rpl44e | LSU ribosomal protein L44E; Binds to the 23S rRNA. (92 aa) |
| | AAZ70522.1 | Conserved hypothetical protein. (797 aa) |
| | pelA | Cell division protein pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (350 aa) |
| | rpoL | DNA-directed RNA polymerase, subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (92 aa) |
| | AAZ70583.1 | Sep-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (386 aa) |
| | cysS | cysteinyl-tRNA synthetase. (471 aa) |
| | lysS-2 | lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (515 aa) |
| | AAZ70682.1 | Histidine triad protein. (139 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (317 aa) |
| | AAZ70725.1 | Conserved hypothetical protein. (182 aa) |
| | AAZ70726.1 | Conserved hypothetical protein. (260 aa) |
| | eif1a | Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (60 aa) |
| | rps15 | SSU ribosomal protein S15P. (152 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (869 aa) |
| | AAZ70944.1 | Hypothetical protein. (276 aa) |
| | leuS | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (966 aa) |
| | serS2 | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). (502 aa) |
| | rps3ae | SSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (207 aa) |
| | eif1a-2 | Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (59 aa) |
| | AAZ71092.1 | GTP-binding protein. (333 aa) |
| | AAZ71176.1 | Acetyltransferase. (189 aa) |
| | eif1a-3 | Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (60 aa) |
| | gatE | glutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (633 aa) |
| | rpl15e | LSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (199 aa) |
| | AAZ71417.1 | Conserved hypothetical protein. (230 aa) |
| | rpl37ae | LSU ribosomal protein L37AE; Binds to the 23S rRNA. (94 aa) |
| | rpoP | DNA-directed RNA polymerase, subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (45 aa) |
| | eif1a1 | Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (96 aa) |
| | eif1a2 | Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (115 aa) |
| | AAZ71549.1 | DNA repair helicase RAD25. (491 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta subunit. (544 aa) |
| | AAZ71721.1 | Long-chain fatty-acid-CoA ligase. (552 aa) |
| | AAZ71741.1 | Serine/threonine protein kinase. (381 aa) |
| | thrS | threonyl-tRNA synthetase / Ser-tRNA(Thr) hydrolase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family. (635 aa) |
| | AAZ71942.1 | Imp4 family protein; Probably involved in the biogenesis of the ribosome. (157 aa) |
| | AAZ71946.1 | GTP-binding protein-like protein; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (258 aa) |
| | AAZ71978.1 | Hypothetical protein. (163 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (444 aa) |
| | rpl21e | LSU ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa) |
| | AAZ72114.1 | DNA-directed RNA polymerase, subunit F. (129 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (287 aa) |
| | AAZ72138.1 | Conserved hypothetical protein. (298 aa) |
| | rlmE | 23S rRNA Um-2552 2'-O-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (263 aa) |
| | rps6e | SSU ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. (139 aa) |
| | infB | Translation initiation factor eaIF-5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (591 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (149 aa) |
| | rpl24e | LSU ribosomal protein L24E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL24 family. (62 aa) |
| | rps28e | SSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. (73 aa) |
| | rpl7ae | LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (120 aa) |
| | AAZ72312.1 | Conserved hypothetical protein. (56 aa) |
| | ef1b | Translation elongation factor 1B (aEF-1B); Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (89 aa) |
| | hisS | histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (409 aa) |
| | rps8e | SSU ribosomal protein S8E. (125 aa) |
| | AAZ72343.1 | Conserved hypothetical protein. (166 aa) |
| | rpl37e | LSU ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (56 aa) |
| | AAZ72371.1 | Small nuclear ribonucleoprotein, LSM family; Belongs to the snRNP Sm proteins family. (72 aa) |
| | hel308 | Helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (729 aa) |
| | AAZ72380.1 | RNase L inhibitor. (588 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (534 aa) |
| | AAZ72450.1 | PAP2 superfamily protein. (355 aa) |
| | AAZ72465.1 | Small nuclear ribonucleoprotein, LSM family. (74 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1058 aa) |
| | AAZ72481.1 | Peptidyl-prolyl cis-trans isomerase. (155 aa) |
| | nac | Nascent polypeptide associated complex NAC; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. (120 aa) |
| | rps10 | SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | tuf | Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (422 aa) |
| | fusA | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] (730 aa) |
| | rps7 | SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (185 aa) |
| | rps12 | SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa) |
| | nusA | Transcription termination factor NusA; Participates in transcription termination. Belongs to the NusA family. (141 aa) |
| | rpl30e | LSU ribosomal protein L30E; Belongs to the eukaryotic ribosomal protein eL30 family. (98 aa) |
| | rpoA2 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (426 aa) |
| | AAZ72555.1 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (880 aa) |
| | AAZ72556.1 | DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (604 aa) |
| | AAZ72557.1 | DNA-directed RNA polymerase, subunit B'; Belongs to the RNA polymerase beta chain family. (531 aa) |
| | rpoH | DNA-directed RNA polymerase, subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (78 aa) |
