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rps4 rps4 truB truB rps5 rps5 rpl19e rpl19e rpl32e rpl32e rnp1 rnp1 rps3 rps3 rps19 rps19 rps24e rps24e AAZ69270.1 AAZ69270.1 rps19e rps19e rpl31e rpl31e eif6 eif6 AAZ69515.1 AAZ69515.1 AAZ69741.1 AAZ69741.1 flpA flpA AAZ69782.1 AAZ69782.1 srp54 srp54 rps17e rps17e srp19 srp19 AAZ70355.1 AAZ70355.1 nop10 nop10 rpl44e rpl44e AAZ70632.1 AAZ70632.1 AAZ70725.1 AAZ70725.1 rps3ae rps3ae rpl15e rpl15e rnp3 rnp3 rnp2 rnp2 rpl37ae rpl37ae AAZ71741.1 AAZ71741.1 rpl24e rpl24e rpl7ae rpl7ae AAZ72343.1 AAZ72343.1 pdxS pdxS rpl30e rpl30e
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rps4SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (216 aa)
truBtRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (338 aa)
rps5SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (208 aa)
rpl19eLSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (150 aa)
rpl32eLSU ribosomal protein L32E; Belongs to the eukaryotic ribosomal protein eL32 family. (145 aa)
rnp1Ribonuclease P protein subunit Rpp29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (110 aa)
rps3SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (311 aa)
rps19SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa)
rps24eSSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (101 aa)
AAZ69270.1SSU processome protein Utp24. (122 aa)
rps19eSSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (149 aa)
rpl31eLSU ribosomal protein L31E; Belongs to the ribosomal protein L31e family. (89 aa)
eif6Translation initiation factor 6 (aeIF-6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (219 aa)
AAZ69515.1Translation initiation factor 1 (eIF-1/SUI1); Belongs to the SUI1 family. (102 aa)
AAZ69741.1Membrane protein. (330 aa)
flpArRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (226 aa)
AAZ69782.1rRNA biogenesis protein Nop56/Nop58. (336 aa)
srp54Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (443 aa)
rps17eSSU ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (64 aa)
srp19Signal recognition particle, subunit SRP19 (srp19); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (103 aa)
AAZ70355.1snoRNP protein GAR1. (86 aa)
nop10Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (51 aa)
rpl44eLSU ribosomal protein L44E; Binds to the 23S rRNA. (92 aa)
AAZ70632.1Conserved hypothetical protein. (172 aa)
AAZ70725.1Conserved hypothetical protein. (182 aa)
rps3aeSSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (207 aa)
rpl15eLSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (199 aa)
rnp3Ribonuclease P protein subunit Rpp30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (239 aa)
rnp2Ribonuclease P protein subunit Rpp14; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (135 aa)
rpl37aeLSU ribosomal protein L37AE; Binds to the 23S rRNA. (94 aa)
AAZ71741.1Serine/threonine protein kinase. (381 aa)
rpl24eLSU ribosomal protein L24E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL24 family. (62 aa)
rpl7aeLSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (120 aa)
AAZ72343.1Conserved hypothetical protein. (166 aa)
pdxSPyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (298 aa)
rpl30eLSU ribosomal protein L30E; Belongs to the eukaryotic ribosomal protein eL30 family. (98 aa)
Your Current Organism:
Methanosarcina barkeri Fusaro
NCBI taxonomy Id: 269797
Other names: M. barkeri str. Fusaro, Methanosarcina barkeri DSM 804, Methanosarcina barkeri str. Fusaro, Methanosarcina barkeri strain Fusaro
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