(12 nodes) Propanoate metabolism, and Limonene and pinene degradation network (Thermobifida fusca)

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second shell of interactors

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gene neighborhood

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Your Input:
	Tfu_0436	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
	Tfu_0744	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (496 aa)
	Tfu_1302	Probable 6-carboxyhexanoate--COA ligase. (692 aa)
	Tfu_1471	Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (490 aa)
	Tfu_1473	Putative pimeloyl-CoA synthetase. (716 aa)
	Tfu_1546	Putative acyl-CoA synthetase. (510 aa)
	Tfu_2239	Conserved hypothetical protein. (659 aa)
	Tfu_2555	propionyl-CoA carboxylase complex B subunit. (534 aa)
	Tfu_2556	Conserved hypothetical protein. (81 aa)
	Tfu_2557	Putative acyl-CoA carboxylase, alpha subunit. (587 aa)
	Tfu_2808	Putative acetyl-coenzyme A synthetase. (581 aa)
	acsA	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (656 aa)

Your Current Organism:

Thermobifida fusca

NCBI taxonomy Id: 269800
Other names: T. fusca YX, Thermobifida fusca YX, Thermobifida fusca str. YX, Thermobifida fusca strain YX

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Tfu_0436	Tfu_1302	Tfu_0436	Tfu_1302	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	Probable 6-carboxyhexanoate--COA ligase.	0.907
Tfu_0436	Tfu_1473	Tfu_0436	Tfu_1473	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	Putative pimeloyl-CoA synthetase.	0.907
Tfu_0436	Tfu_1546	Tfu_0436	Tfu_1546	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	Putative acyl-CoA synthetase.	0.931
Tfu_0436	Tfu_2239	Tfu_0436	Tfu_2239	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	Conserved hypothetical protein.	0.934
Tfu_0436	Tfu_2557	Tfu_0436	Tfu_2557	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	Putative acyl-CoA carboxylase, alpha subunit.	0.923
Tfu_0436	Tfu_2808	Tfu_0436	Tfu_2808	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	Putative acetyl-coenzyme A synthetase.	0.931
Tfu_0436	acsA	Tfu_0436	Tfu_2856	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.931
Tfu_0744	Tfu_1302	Tfu_0744	Tfu_1302	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	Probable 6-carboxyhexanoate--COA ligase.	0.900
Tfu_0744	Tfu_1471	Tfu_0744	Tfu_1471	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.920
Tfu_0744	Tfu_1473	Tfu_0744	Tfu_1473	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	Putative pimeloyl-CoA synthetase.	0.900
Tfu_0744	Tfu_1546	Tfu_0744	Tfu_1546	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	Putative acyl-CoA synthetase.	0.927
Tfu_0744	Tfu_2239	Tfu_0744	Tfu_2239	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	Conserved hypothetical protein.	0.821
Tfu_0744	Tfu_2555	Tfu_0744	Tfu_2555	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	propionyl-CoA carboxylase complex B subunit.	0.810
Tfu_0744	Tfu_2557	Tfu_0744	Tfu_2557	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	Putative acyl-CoA carboxylase, alpha subunit.	0.805
Tfu_0744	Tfu_2808	Tfu_0744	Tfu_2808	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	Putative acetyl-coenzyme A synthetase.	0.927
Tfu_0744	acsA	Tfu_0744	Tfu_2856	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.927
Tfu_1302	Tfu_0436	Tfu_1302	Tfu_0436	Probable 6-carboxyhexanoate--COA ligase.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.907
Tfu_1302	Tfu_0744	Tfu_1302	Tfu_0744	Probable 6-carboxyhexanoate--COA ligase.	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	0.900
Tfu_1302	Tfu_1471	Tfu_1302	Tfu_1471	Probable 6-carboxyhexanoate--COA ligase.	Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.900
Tfu_1302	Tfu_1473	Tfu_1302	Tfu_1473	Probable 6-carboxyhexanoate--COA ligase.	Putative pimeloyl-CoA synthetase.	0.921