STRINGSTRING
Tfu_0003 Tfu_0003 Tfu_0273 Tfu_0273 eno eno Tfu_0464 Tfu_0464 Tfu_1033 Tfu_1033 pfp pfp Tfu_1179 Tfu_1179 Tfu_1811 Tfu_1811 Tfu_2002 Tfu_2002 tal tal Tfu_2004 Tfu_2004 zwf zwf Tfu_2006 Tfu_2006 pgl pgl tpiA tpiA pgk pgk Tfu_2017 Tfu_2017 Tfu_2114 Tfu_2114 Tfu_2315 Tfu_2315 Tfu_2487 Tfu_2487 Tfu_2488 Tfu_2488 Tfu_2489 Tfu_2489 Tfu_2508 Tfu_2508 Tfu_2765 Tfu_2765 Tfu_2814 Tfu_2814 gpmA gpmA Tfu_2970 Tfu_2970 ackA ackA Tfu_2972 Tfu_2972 Tfu_3010 Tfu_3010
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tfu_00036-phosphogluconate dehydrogenase (decarboxylating). (294 aa)
Tfu_0273Glucokinase. (361 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
Tfu_0464GlpX. (341 aa)
Tfu_1033Glucokinase. (315 aa)
pfpPyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa)
Tfu_1179Pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa)
Tfu_1811Polyphosphate glucokinase. (262 aa)
Tfu_2002Transketolase; Belongs to the transketolase family. (707 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (368 aa)
Tfu_2004Glucose-6-phosphate isomerase. (544 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (534 aa)
Tfu_2006Conserved hypothetical protein. (308 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (261 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa)
Tfu_2017Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
Tfu_2114Gluconate kinase. (170 aa)
Tfu_2315Putative secreted protein. (353 aa)
Tfu_2487Phosphoryl transfer system, HPr. (87 aa)
Tfu_2488HAD-superfamily hydrolase subfamily IA, variant 3. (237 aa)
Tfu_2489Putative phosphoenolpyruvate-dependent sugar phosphotransferase. (149 aa)
Tfu_2508Conserved hypothetical protein. (369 aa)
Tfu_2765Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (565 aa)
Tfu_2814Putative dehydrogenase. (349 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa)
Tfu_2970Fructose-6-phosphate phosphoketolase. (792 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (361 aa)
Tfu_2972Conserved hypothetical protein. (140 aa)
Tfu_3010Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
Your Current Organism:
Thermobifida fusca
NCBI taxonomy Id: 269800
Other names: T. fusca YX, Thermobifida fusca YX, Thermobifida fusca str. YX, Thermobifida fusca strain YX
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