STRINGSTRING
Tfu_0176 Tfu_0176 Tfu_0275 Tfu_0275 Tfu_0696 Tfu_0696 menA menA Tfu_0888 Tfu_0888 Tfu_0907 Tfu_0907 menC menC Tfu_0966 Tfu_0966 Tfu_1188 Tfu_1188 Tfu_1216 Tfu_1216 Tfu_1217 Tfu_1217 Tfu_1218 Tfu_1218 Tfu_1219 Tfu_1219 Tfu_1220 Tfu_1220 Tfu_1221 Tfu_1221 Tfu_1222 Tfu_1222 Tfu_1223 Tfu_1223 Tfu_1224 Tfu_1224 Tfu_1225 Tfu_1225 Tfu_1226 Tfu_1226 Tfu_1227 Tfu_1227 Tfu_1230 Tfu_1230 Tfu_1231 Tfu_1231 Tfu_1242 Tfu_1242 Tfu_1283 Tfu_1283 Tfu_1408 Tfu_1408 menB menB menC-2 menC-2 menD menD Tfu_1413 Tfu_1413 Tfu_1466 Tfu_1466 Tfu_1841 Tfu_1841 Tfu_1842 Tfu_1842 Tfu_1843 Tfu_1843 Tfu_1851 Tfu_1851 Tfu_1854 Tfu_1854 Tfu_1855 Tfu_1855 Tfu_1859 Tfu_1859 Tfu_1860 Tfu_1860 Tfu_1861 Tfu_1861 Tfu_1863 Tfu_1863 Tfu_1865 Tfu_1865 Tfu_1866 Tfu_1866 Tfu_1867 Tfu_1867 Tfu_1868 Tfu_1868 Tfu_1869 Tfu_1869 Tfu_1870 Tfu_1870 Tfu_1871 Tfu_1871 Tfu_1872 Tfu_1872 Tfu_1873 Tfu_1873 Tfu_1960 Tfu_1960 Tfu_1973 Tfu_1973 fabH fabH Tfu_1976 Tfu_1976 Tfu_2308 Tfu_2308 Tfu_2316 Tfu_2316 menG menG Tfu_2981 Tfu_2981
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tfu_0176Putative short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (240 aa)
Tfu_0275Putative short chain dehydrogenase. (257 aa)
Tfu_0696Putative 6-phosphofructokinase : 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (328 aa)
menA1,4-Dihydroxy-2-naphtoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (289 aa)
Tfu_0888Ketoacyl reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (355 aa)
Tfu_0907Transcriptional regulator, DeoR family. (274 aa)
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (376 aa)
Tfu_0966caffeoyl-CoA O-methyltransferase. (219 aa)
Tfu_1188Phenylacetic acid degradation-related protein. (141 aa)
Tfu_1216Conserved hypothetical protein. (486 aa)
Tfu_1217Putative cyclase II. (109 aa)
Tfu_1218Actinorhodin polyketide beta-ketoacyl synthase alpha subunit / 3-oxoacyl-ACP synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (420 aa)
Tfu_1219Actinorhodin polyketide beta-ketoacyl synthase beta subunit / 3-oxoacyl-ACP synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (402 aa)
Tfu_1220Actinorhodin polyketide synthase acyl carrier protein / 3-oxoacyl-ACP synthase acyl carrier protein. (86 aa)
Tfu_1221Ketoacyl reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
Tfu_1222Actinorhodin polyketide synthase bifunctional cyclase/dehydratase. (314 aa)
Tfu_1223Putative rifampin monooxygenase. (471 aa)
Tfu_1224Putative 3-oxoacyl-(acyl-carrier protein) reductase. (255 aa)
Tfu_1225Putative cytochrome P450. (392 aa)
Tfu_1226Hypothetical protein. (64 aa)
Tfu_1227Putative ferredoxin reductase. (414 aa)
Tfu_1230Conserved hypothetical protein. (211 aa)
Tfu_1231Modular polyketide synthase. (333 aa)
Tfu_1242Putative oxidoreductase. (308 aa)
Tfu_1283Probable short-chain type dehydrogenase/reductase. (277 aa)
Tfu_1408Putative ortho-succinylbenzoate-CoA synthetase. (391 aa)
menB1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (279 aa)
menC-2o-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (317 aa)
menD2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (553 aa)
Tfu_1413Isochorismate synthase. (407 aa)
Tfu_1466Short-chain alcohol dehydrogenase. (267 aa)
Tfu_1841Putative 3-ketoacyl-CoA reductase. (250 aa)
Tfu_1842Enoyl-[acyl-carrier-protein] reductase (NADH). (254 aa)
Tfu_18433-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (234 aa)
Tfu_1851Regulatory protein, DeoR. (264 aa)
Tfu_1854Regulatory protein, DeoR. (252 aa)
Tfu_18554'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (284 aa)
Tfu_1859Hypothetical protein. (97 aa)
Tfu_1860Iron-chelator utilization protein. (273 aa)
Tfu_1861Probable POT family transport protein. (443 aa)
Tfu_1863Putative conserved protein MbtH. (74 aa)
Tfu_1865Amino acid adenylation. (1344 aa)
Tfu_1866Amino acid adenylation. (1074 aa)
Tfu_1867Non-ribosomal peptide synthase:Amino acid adenylation. (3629 aa)
Tfu_1868Isochorismatase. (84 aa)
Tfu_1869Putative peptide monooxygenase. (438 aa)
Tfu_1870Isochorismatase. (221 aa)
Tfu_18712,3-dihydroxybenzoate-AMP ligase. (543 aa)
Tfu_1872Isochorismate synthase. (393 aa)
Tfu_18732,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; RBL00455. (260 aa)
Tfu_1960Conserved hypothetical protein. (96 aa)
Tfu_1973(Acyl-carrier protein) S-malonyltransferase. (319 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (317 aa)
Tfu_19763-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
Tfu_2308Putative 3-oxoacyl-ACP reductase. (252 aa)
Tfu_2316Thioesterase II. (242 aa)
menGDemethylmenaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (236 aa)
Tfu_2981Conserved hypothetical protein. (149 aa)
Your Current Organism:
Thermobifida fusca
NCBI taxonomy Id: 269800
Other names: T. fusca YX, Thermobifida fusca YX, Thermobifida fusca str. YX, Thermobifida fusca strain YX
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