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| | Tfu_0067 | Short chain enoyl-CoA hydratase / Enoyl-CoA hydratase. (256 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (604 aa) |
| | nth | Endonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (258 aa) |
| | Tfu_0153 | Pectate lyase/Amb allergen. (449 aa) |
| | Tfu_0188 | 2-keto-3-deoxy-phosphogluconate aldolase. (210 aa) |
| | Tfu_0193 | Similar to Carbonic anhydrases/acetyltransferases isoleucine patch superfamily. (205 aa) |
| | Tfu_0226 | L-threonine synthase. (428 aa) |
| | ectC | Putative condensing enzyme; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (134 aa) |
| | Tfu_0341 | citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (318 aa) |
| | moaC | GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (162 aa) |
| | Tfu_0396 | Conserved hypothetical protein. (186 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | fumC | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | Tfu_0501 | Enoyl-CoA hydratase. (263 aa) |
| | Tfu_0534 | Deoxyribodipyrimidine photo-lyase type I; Belongs to the DNA photolyase family. (419 aa) |
| | Tfu_0562 | Malate dehydrogenase (oxaloacetate decarboxylating). (428 aa) |
| | Tfu_0566 | 2-oxoglutarate dehydrogenase E1 component. (1214 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (465 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (195 aa) |
| | mutM | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (296 aa) |
| | Tfu_0694 | Putative DNA repair hydrolase; Belongs to the FPG family. (292 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (325 aa) |
| | Tfu_0958 | Conserved hypothetical protein. (151 aa) |
| | Tfu_1039 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (348 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (233 aa) |
| | Tfu_1064 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (412 aa) |
| | ribBA | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (410 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (406 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (368 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (197 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (268 aa) |
| | trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (412 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (270 aa) |
| | Tfu_1217 | Putative cyclase II. (109 aa) |
| | Tfu_1259 | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (250 aa) |
| | Tfu_1285 | citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (302 aa) |
| | Tfu_1286 | Possible dehydratase, MaoC family. (159 aa) |
| | Tfu_1297 | Amidohydrolase family protein. (262 aa) |
| | Tfu_1299 | Dihydroxynaphthoic acid synthase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa) |
| | Tfu_1312 | Conserved hypothetical protein. (170 aa) |
| | Tfu_1313 | Putative citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (275 aa) |
| | moaA | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa) |
| | Tfu_1377 | Isocitrate lyase. (429 aa) |
| | menB | 1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (279 aa) |
| | menC-2 | o-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (317 aa) |
| | Tfu_1454 | Hypothetical protein. (129 aa) |
| | Tfu_1460 | Conserved hypothetical protein. (735 aa) |
| | Tfu_1483 | Conserved hypothetical protein. (152 aa) |
| | Tfu_1485 | Conserved hypothetical protein. (134 aa) |
| | rlpA | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (233 aa) |
| | Tfu_1547 | Pterin-4-alpha-carbinolamine dehydratase. (94 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa) |
| | Tfu_1715 | Dihydrodipicolinate synthase. (288 aa) |
| | Tfu_1718 | Putative dihydrodipicolinate synthase; Belongs to the DapA family. (301 aa) |
| | Tfu_1720 | Conserved hypothetical protein. (388 aa) |
| | Tfu_1741 | L-threonine ammonia-lyase. (310 aa) |
| | panD | L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (137 aa) |
| | Tfu_1890 | Putative secreted protein. (255 aa) |
| | psd | Phosphatidylserine decarboxylase-related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (217 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (361 aa) |
| | Tfu_1925 | Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (916 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (343 aa) |
| | Tfu_1966 | Protein of unknown function UPF0047. (142 aa) |
| | Tfu_2046 | Conserved hypothetical protein. (308 aa) |
| | argH | Argininosuccinate lyase. (476 aa) |
| | mltG | Putative integral membrane protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (685 aa) |
| | pdxT | Putative glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (201 aa) |
| | pdxS | Vitamin B6 biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (362 aa) |
| | Tfu_2132 | Carbonic anhydrase, putative. (167 aa) |
| | Tfu_2168 | Pectate lyase. (512 aa) |
| | ilvD | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (625 aa) |
| | cobD | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (322 aa) |
| | murQ | Putative phophosugar-binding protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (304 aa) |
| | Tfu_2354 | Conserved hypothetical protein. (134 aa) |
| | Tfu_2357 | Conserved hypothetical protein. (401 aa) |
| | Tfu_2390 | Malate dehydrogenase (oxaloacetate decarboxylating). (470 aa) |
| | Tfu_2395 | methylmalonyl-CoA epimerase. (147 aa) |
| | Tfu_2423 | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (354 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (461 aa) |
| | Tfu_2430 | Conserved hypothetical protein. (229 aa) |
| | Tfu_2519 | FO synthase subunit 1 / FO synthase subunit 2. (871 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (385 aa) |
| | Tfu_2552 | Adenylate cyclase. (336 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (875 aa) |
| | Tfu_2560 | Conserved hypothetical protein. (149 aa) |
| | nnrD | Protein of unknown function UPF0031:YjeF-related protein, N-terminal; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hyd [...] (490 aa) |
| | Tfu_2666 | Conserved hypothetical protein; Belongs to the UPF0336 family. (152 aa) |
| | Tfu_2727 | Protein of unknown function 1935; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (163 aa) |
| | Tfu_2730 | Porphobilinogen synthase; Belongs to the ALAD family. (327 aa) |
| | Tfu_2731 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase. (563 aa) |
| | Tfu_2891 | Dihydroneopterin aldolase family:Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (126 aa) |
| | ispF | MECDP-synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (154 aa) |
| | Tfu_2970 | Fructose-6-phosphate phosphoketolase. (792 aa) |
| | Tfu_3010 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa) |
| | Tfu_3014 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa) |
| | pheA | Prephenate dehydratase. (315 aa) |
