(14 nodes) ATP-grasp fold network (Thermobifida fusca)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	Tfu_2128	Conserved hypothetical protein. (907 aa)
	Tfu_2557	Putative acyl-CoA carboxylase, alpha subunit. (587 aa)
	sucC	succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (410 aa)
	purD	Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (424 aa)
	ddl	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (371 aa)
	Tfu_0737	Hypothetical protein. (385 aa)
	Tfu_0947	Putative acetyl/propionyl CoA carboxylase alpha subunit: biotin carboxylase. (696 aa)
	carB	Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1103 aa)
	Tfu_1228	Putative acyl-CoA carboxylase complex A subunit. (589 aa)
	Tfu_1302	Probable 6-carboxyhexanoate--COA ligase. (692 aa)
	Tfu_1473	Putative pimeloyl-CoA synthetase. (716 aa)
	Tfu_1530	Similar to Acetyl/propionyl-CoA carboxylase alpha subunit. (1849 aa)
	ddl-2	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (329 aa)
	purK	Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (385 aa)

Your Current Organism:

Thermobifida fusca

NCBI taxonomy Id: 269800
Other names: T. fusca YX, Thermobifida fusca YX, Thermobifida fusca str. YX, Thermobifida fusca strain YX

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Tfu_0947	Tfu_1228	Tfu_0947	Tfu_1228	Putative acetyl/propionyl CoA carboxylase alpha subunit: biotin carboxylase.	Putative acyl-CoA carboxylase complex A subunit.	0.918
Tfu_0947	Tfu_1302	Tfu_0947	Tfu_1302	Putative acetyl/propionyl CoA carboxylase alpha subunit: biotin carboxylase.	Probable 6-carboxyhexanoate--COA ligase.	0.900
Tfu_0947	Tfu_1473	Tfu_0947	Tfu_1473	Putative acetyl/propionyl CoA carboxylase alpha subunit: biotin carboxylase.	Putative pimeloyl-CoA synthetase.	0.900
Tfu_0947	Tfu_1530	Tfu_0947	Tfu_1530	Putative acetyl/propionyl CoA carboxylase alpha subunit: biotin carboxylase.	Similar to Acetyl/propionyl-CoA carboxylase alpha subunit.	0.816
Tfu_0947	Tfu_2557	Tfu_0947	Tfu_2557	Putative acetyl/propionyl CoA carboxylase alpha subunit: biotin carboxylase.	Putative acyl-CoA carboxylase, alpha subunit.	0.918
Tfu_0947	sucC	Tfu_0947	Tfu_2577	Putative acetyl/propionyl CoA carboxylase alpha subunit: biotin carboxylase.	succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.833
Tfu_1228	Tfu_0947	Tfu_1228	Tfu_0947	Putative acyl-CoA carboxylase complex A subunit.	Putative acetyl/propionyl CoA carboxylase alpha subunit: biotin carboxylase.	0.918
Tfu_1228	Tfu_1302	Tfu_1228	Tfu_1302	Putative acyl-CoA carboxylase complex A subunit.	Probable 6-carboxyhexanoate--COA ligase.	0.900
Tfu_1228	Tfu_1473	Tfu_1228	Tfu_1473	Putative acyl-CoA carboxylase complex A subunit.	Putative pimeloyl-CoA synthetase.	0.900
Tfu_1228	Tfu_1530	Tfu_1228	Tfu_1530	Putative acyl-CoA carboxylase complex A subunit.	Similar to Acetyl/propionyl-CoA carboxylase alpha subunit.	0.808
Tfu_1228	Tfu_2557	Tfu_1228	Tfu_2557	Putative acyl-CoA carboxylase complex A subunit.	Putative acyl-CoA carboxylase, alpha subunit.	0.904
Tfu_1228	sucC	Tfu_1228	Tfu_2577	Putative acyl-CoA carboxylase complex A subunit.	succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.833
Tfu_1302	Tfu_0947	Tfu_1302	Tfu_0947	Probable 6-carboxyhexanoate--COA ligase.	Putative acetyl/propionyl CoA carboxylase alpha subunit: biotin carboxylase.	0.900
Tfu_1302	Tfu_1228	Tfu_1302	Tfu_1228	Probable 6-carboxyhexanoate--COA ligase.	Putative acyl-CoA carboxylase complex A subunit.	0.900
Tfu_1302	Tfu_1473	Tfu_1302	Tfu_1473	Probable 6-carboxyhexanoate--COA ligase.	Putative pimeloyl-CoA synthetase.	0.921
Tfu_1302	Tfu_2557	Tfu_1302	Tfu_2557	Probable 6-carboxyhexanoate--COA ligase.	Putative acyl-CoA carboxylase, alpha subunit.	0.900
Tfu_1302	sucC	Tfu_1302	Tfu_2577	Probable 6-carboxyhexanoate--COA ligase.	succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.805
Tfu_1473	Tfu_0947	Tfu_1473	Tfu_0947	Putative pimeloyl-CoA synthetase.	Putative acetyl/propionyl CoA carboxylase alpha subunit: biotin carboxylase.	0.900
Tfu_1473	Tfu_1228	Tfu_1473	Tfu_1228	Putative pimeloyl-CoA synthetase.	Putative acyl-CoA carboxylase complex A subunit.	0.900
Tfu_1473	Tfu_1302	Tfu_1473	Tfu_1302	Putative pimeloyl-CoA synthetase.	Probable 6-carboxyhexanoate--COA ligase.	0.921