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trpB trpB trpC trpC AFZ57008.1 AFZ57008.1 trpD trpD trpF trpF trpC-2 trpC-2 AFZ59098.1 AFZ59098.1 trpE trpE trpA trpA AFZ60021.1 AFZ60021.1 AFZ60780.1 AFZ60780.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
Predicted Interactions
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gene co-occurrence
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Your Input:
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (412 aa)
trpCPFAM: Indole-3-glycerol phosphate synthase; COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: naz:Aazo_3804 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase 2; Belongs to the TrpC family. (291 aa)
AFZ57008.1PFAM: Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; COGs: COG0547 Anthranilate phosphoribosyltransferase; InterPro IPR017459:IPR000312; KEGG: npu:Npun_F1535 hypothetical protein; PFAM: Glycosyl transferase, family 3, N-terminal; Glycosyl transferase, family 3; SPTR: Glycosyl transferase, family 3. (349 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (350 aa)
trpFPFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: naz:Aazo_3378 phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (209 aa)
trpC-2PFAM: Indole-3-glycerol phosphate synthase; COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: naz:Aazo_0100 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase 1; Belongs to the TrpC family. (294 aa)
AFZ59098.1Para-aminobenzoate synthase, subunit I; PFAM: Glutamine amidotransferase class-I; chorismate binding enzyme; Anthranilate synthase component I, N terminal region; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; aminodeoxychorismate synthase, component I, bacterial clade; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterProIPR006221:IPR005802:IPR000991:IPR006805:IPR 015890; KEGG: npu:Npun_R3717 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Glutamine amidotransferase class-I, C-terminal [...] (750 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (504 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)
AFZ60021.1PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991:IPR006221; KEGG: naz:Aazo_4993 anthranilate synthase glutamine amidotransferase; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Glutamine amidotransferase of anthranilate synthase; TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain. (199 aa)
AFZ60780.1Anthranilate synthase; PFAM: chorismate binding enzyme; TIGRFAM: salicylate synthase; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR015890; KEGG: amr:AM1_A0247 chorismate-binding domain-containing protein; PFAM: Chorismate binding, C-terminal; PRIAM: Anthranilate synthase; SPTR: Putative chorismate binding domain protein. (440 aa)
Your Current Organism:
Anabaena cylindrica
NCBI taxonomy Id: 272123
Other names: A. cylindrica PCC 7122, Anabaena cylindrica IAM M-1, Anabaena cylindrica NIES-19, Anabaena cylindrica PCC 7122, Anabaena cylindrica UTEX B 629, Anabaena sp. ATCC 27899, Anabaena sp. PCC 7122
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