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mtnA mtnA gshB gshB AFZ55821.1 AFZ55821.1 thiL thiL AFZ55914.1 AFZ55914.1 AFZ56002.1 AFZ56002.1 AFZ56080.1 AFZ56080.1 AFZ56253.1 AFZ56253.1 dxs dxs AFZ56465.1 AFZ56465.1 thiG thiG AFZ56583.1 AFZ56583.1 pdhA pdhA AFZ56690.1 AFZ56690.1 AFZ56775.1 AFZ56775.1 AFZ56930.1 AFZ56930.1 thiC thiC accD accD ackA ackA AFZ57600.1 AFZ57600.1 metK metK AFZ57823.1 AFZ57823.1 AFZ58120.1 AFZ58120.1 mtnP mtnP sat sat AFZ58146.1 AFZ58146.1 AFZ58313.1 AFZ58313.1 lipA lipA acsA acsA AFZ58533.1 AFZ58533.1 folD folD bioB bioB accA accA AFZ58860.1 AFZ58860.1 AFZ58941.1 AFZ58941.1 cysC cysC AFZ59241.1 AFZ59241.1 AFZ59345.1 AFZ59345.1 AFZ59793.1 AFZ59793.1 AFZ59890.1 AFZ59890.1 bioD bioD thiE thiE AFZ59980.1 AFZ59980.1 lipA-2 lipA-2 AFZ60201.1 AFZ60201.1 AFZ60273.1 AFZ60273.1 AFZ60475.1 AFZ60475.1 AFZ60779.1 AFZ60779.1 asd asd
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (352 aa)
gshBPFAM: Prokaryotic glutathione synthetase, N-terminal domain; Prokaryotic glutathione synthetase, ATP-grasp domain; TIGRFAM: glutathione synthetase, prokaryotic; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); HAMAP: Glutathione synthetase, prokaryotic; InterPro IPR006284:IPR004215:IPR004218; KEGG: npu:Npun_F4803 glutathione synthetase; PFAM: Prokaryotic glutathione synthetase, ATP-binding; Prokaryotic glutathione synthetase, N-terminal; PRIAM: Glutathione synthase; SPTR: Glutathione synthetase; TIGRFAM: Glutathione synthetase, proka [...] (323 aa)
AFZ55821.1PFAM: Serine acetyltransferase, N-terminal; Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: ana:alr1404 serine acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine acetyltransferase; TIGRFAM: Serine O-acetyltransferase. (242 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (338 aa)
AFZ55914.1LmbE family protein; PFAM: GlcNAc-PI de-N-acetylase; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: naz:Aazo_3114 LmbE family protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: LmbE family protein. (258 aa)
AFZ56002.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
AFZ56080.1KEGG: naz:Aazo_1861 hexapaptide repeat-containing transferase; SPTR: Hexapaptide repeat-containing transferase. (254 aa)
AFZ56253.1Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: naz:Aazo_1439 hypothetical protein; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding; SPTR: Catalytic [...] (434 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (636 aa)
AFZ56465.1Sulphatase-modifying factor protein; PFAM: Formylglycine-generating sulfatase enzyme; TIGRFAM: TIGR03440 family protein; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: naz:Aazo_3409 hypothetical protein; PFAM: Sulphatase-modifying factor; SPTR: Putative uncharacterized protein. (451 aa)
thiGThiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (658 aa)
AFZ56583.1Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: naz:Aazo_1129 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. (250 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (345 aa)
AFZ56690.1Acireductone dioxygenase apoprotein; PFAM: ARD/ARD' family; COGs: COG1791 conserved hypothetical protein contains double-stranded beta-helix domain; KEGG: ana:all2724 hypothetical protein; PRIAM: Acireductone dioxygenase (Fe(2+)-requiring); SPTR: Acireductone dioxygenase. (184 aa)
AFZ56775.1Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: npu:Npun_F5408 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; Belongs to the cysteine synthase/cystathionine beta- synthase family. (320 aa)
AFZ56930.1Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
thiCHydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (457 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (316 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa)
AFZ57600.1PFAM: Plasmid recombination enzyme; InterPro IPR001668; KEGG: npu:Npun_BR213 plasmid recombination enzyme; PFAM: Plasmid recombination enzyme; SPTR: Plasmid recombination enzyme. (636 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (424 aa)
AFZ57823.1PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: naz:Aazo_4841 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase. (429 aa)
AFZ58120.1Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1176 aa)
mtnPMethylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (290 aa)
satSulfate adenylyltransferase; PFAM: ATP-sulfurylase; TIGRFAM: ATP sulphurylase; COGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); HAMAP: Sulphate adenylyltransferase, subgroup; InterPro IPR002650:IPR020792; KEGG: naz:Aazo_1579 sulfate adenylyltransferase; PFAM: Sulphate adenylyltransferase; PRIAM: Sulfate adenylyltransferase; SPTR: Sulfate adenylyltransferase; TIGRFAM: Sulphate adenylyltransferase; Belongs to the sulfate adenylyltransferase family. (393 aa)
AFZ58146.1PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: naz:Aazo_2809 hypothetical protein; PFAM: Domain of unknown function DUF39; SPTR: Putative uncharacterized protein. (389 aa)
AFZ58313.1Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: ana:all1169 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase. (363 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (289 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (656 aa)
AFZ58533.1PFAM: Protein of unknown function (DUF3137); KEGG: pmf:P9303_21011 galanin; SPTR: Possible Galanin. (649 aa)
folD5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (292 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (334 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (326 aa)
AFZ58860.1Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005859:IPR005856; KEGG: naz:Aazo_3782 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; Belongs to the cysteine synthase/cystathionine beta- synthase family. (320 aa)
AFZ58941.1PFAM: DRTGG domain; COGs: COG0857 BioD-like N-terminal domain of phosphotransacetylase; InterPro IPR010766; KEGG: naz:Aazo_3303 DRTGG domain-containing protein; PFAM: DRTGG; SPTR: DRTGG domain protein. (364 aa)
cysCAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (184 aa)
AFZ59241.1Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: ava:Ava_1347 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase. (324 aa)
AFZ59345.1UDP-sulfoquinovose synthase; PFAM: NAD dependent epimerase/dehydratase family; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: naz:Aazo_3746 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-sulfoquinovose synthase; SPTR: NAD-dependent epimerase/dehydratase. (384 aa)
AFZ59793.18-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (393 aa)
AFZ59890.1PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004399; KEGG: naz:Aazo_0366 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Phosphomethylpyrimidine kinase; SPTR: Phosphomethylpyrimidine kinase; TIGRFAM: Phosphomethylpyrimidine kinase type-2. (275 aa)
bioDDethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (229 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (347 aa)
AFZ59980.1PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS; InterPro IPR003749:IPR010035; KEGG: naz:Aazo_3313 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis. (70 aa)
lipA-2Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (300 aa)
AFZ60201.1Sulfurtransferase DndC; PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: putative sulfurtransferase DndC; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR017598:IPR002500; KEGG: npu:Npun_F4491 hypothetical protein; PFAM: Phosphoadenosine phosphosulphate reductase; SPTR: Phosphoadenosine phosphosulfate reductase; TIGRFAM: Putative sulfurtransferase DndC. (541 aa)
AFZ60273.1Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: ava:Ava_0452 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; Belongs to the cysteine synthase/cystathionine beta- synthase family. (313 aa)
AFZ60475.1Assimilatory nitrite reductase (ferredoxin) precursor; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: precorrin-3B synthase; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR012798:IPR005117:IPR006067; KEGG: naz:Aazo_0121 precorrin-3B synthase; PFAM: Nitrite/sulphite reductase 4Fe-4S domain; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; PRIAM: Ferredoxin--nitrite reductase; SPTR: Precorrin-3B synthase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobG-like. (516 aa)
AFZ60779.1benzoate-CoA ligase family; PFAM: AMP-binding enzyme; TIGRFAM: benzoate-CoA ligase family; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR011957; KEGG: amr:AM1_A0246 benzoate-CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Benzoate--CoA ligase; SPTR: Benzoate-CoA ligase; TIGRFAM: Benzoate-CoA ligase family. (524 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (345 aa)
Your Current Organism:
Anabaena cylindrica
NCBI taxonomy Id: 272123
Other names: A. cylindrica PCC 7122, Anabaena cylindrica IAM M-1, Anabaena cylindrica NIES-19, Anabaena cylindrica PCC 7122, Anabaena cylindrica UTEX B 629, Anabaena sp. ATCC 27899, Anabaena sp. PCC 7122
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