STRINGSTRING
hemA hemA trkA trkA fabG fabG APE_2507.1 APE_2507.1 proC proC adh adh gyaR gyaR APE_1660.1 APE_1660.1 APE_1557.1 APE_1557.1 ino1 ino1 sirC sirC APE_1484.1 APE_1484.1 lysY lysY gdhA gdhA APE_1361.1 APE_1361.1 APE_1265.1 APE_1265.1 APE_1245.1 APE_1245.1 rfbB rfbB rfbD rfbD hom hom asd asd sucD sucD ocd ocd APE_0912 APE_0912 APE_0763.1 APE_0763.1 APE_0756.1 APE_0756.1 mdh mdh ahcY ahcY aroE aroE APE_0562.1 APE_0562.1 APE_0392 APE_0392 APE_0193.1 APE_0193.1 gap gap
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (416 aa)
trkATrk system potassium uptake protein TrkA. (220 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase. (250 aa)
APE_2507.1Putative glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (279 aa)
adhNAD-dependent alcohol dehydrogenase. (344 aa)
gyaRGlyoxylate reductase. (335 aa)
APE_1660.1Conserved hypothetical protein. (148 aa)
APE_1557.1Putative alcohol dehydrogenase. (312 aa)
ino1Inositol-3-phosphate synthase. (392 aa)
sirCPrecorrin-2 dehydrogenase. (220 aa)
APE_1484.13-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA dehydratase. (669 aa)
lysYN-acetyl-gamma-aminoadipyl-phosphate reductase/N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (355 aa)
gdhANADP-dependent glutamate dehydrogenase; GDH; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (418 aa)
APE_1361.1Putative oxidoreductase. (260 aa)
APE_1265.1Putative glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (347 aa)
APE_1245.1Putative zinc-binding dehydrogenase. (326 aa)
rfbBdTDP-glucose 4,6-dehydratase; RmlB. (330 aa)
rfbDdTDP-4-dehydrorhamnose reductase; RmlD. (300 aa)
homHomoserine dehydrogenase; HDH. (332 aa)
asdAspartate-semialdehyde dehydrogenase; ASADH. (349 aa)
sucDsuccinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa)
ocdPutative ornithine cyclodeaminase. (290 aa)
APE_0912Putative dehydrogenase. (260 aa)
APE_0763.1Hypothetical protein. (322 aa)
APE_0756.1Putative dehydrogenase. (291 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate. Can utilize both NAD and NADP. Catalytic efficiency for malate oxidation is 3-fold higher with NADP. Belongs to the LDH/MDH superfamily. (308 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (416 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa)
APE_0562.1Putative prephenate dehydrogenase. (268 aa)
APE_0392Malate dehydrogenase; Malic enzyme. (446 aa)
APE_0193.1L-lysine 6-dehydrogenase. (367 aa)
gapGlyceraldehyde 3-phosphate dehydrogenase; GAPDH. (343 aa)
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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