STRINGSTRING
loxD loxD mdh mdh APE_0766 APE_0766 APE_0929.1 APE_0929.1 gcvH gcvH APE_0996.1 APE_0996.1 acsA acsA citB citB pdhD pdhD APE_1686.1 APE_1686.1 APE_1687 APE_1687 gcvT gcvT gltA gltA gyaR gyaR glyA glyA APE_2108 APE_2108 gcvPB gcvPB gcvPA gcvPA glnA glnA APE_2382.1 APE_2382.1 APE_2384 APE_2384 APE_2507.1 APE_2507.1 acsA-2 acsA-2 acsA-3 acsA-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
loxDD-lactate dehydrogenase. (473 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate. Can utilize both NAD and NADP. Catalytic efficiency for malate oxidation is 3-fold higher with NADP. Belongs to the LDH/MDH superfamily. (308 aa)
APE_0766Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (239 aa)
APE_0929.1Putative 3-ketoacyl-CoA thiolase. (397 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (143 aa)
APE_0996.1Glycerate kinase. (448 aa)
acsAAcetyl-coenzyme A synthetase. (656 aa)
citBAconitate hydratase; Aconitase. (903 aa)
pdhDDihydrolipoyl dehydrogenase; Glycine cleavage system L protein; pyruvate dehydrogenase complex, E3 component. (464 aa)
APE_1686.1Coenzyme B12-dependent mutase. (161 aa)
APE_1687Coenzyme B12-dependent mutase. (565 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (375 aa)
gltACitrate synthase. (394 aa)
gyaRGlyoxylate reductase. (335 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity). (439 aa)
APE_2108acetyl-CoA acetyltransferase. (402 aa)
gcvPBGlycine cleavage system P-protein subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (520 aa)
gcvPAGlycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (465 aa)
glnAGlutamine synthetase; Glutamate--ammonia ligase; Belongs to the glutamine synthetase family. (458 aa)
APE_2382.1Conserved hypothetical protein. (385 aa)
APE_2384Conserved hypothetical protein. (394 aa)
APE_2507.1Putative glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)
acsA-2Acetyl-coenzyme A synthetase. (513 aa)
acsA-3Acetyl-coenzyme A synthetase. (140 aa)
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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