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| | fba | Fructose-bisphosphate aldolase class I; Belongs to the DeoC/FbaB aldolase family. (272 aa) |
| | ilvD | Dihydroxy-acid dehydratase; DAD; Belongs to the IlvD/Edd family. (553 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (489 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (279 aa) |
| | agt | Alanine glyoxylate transaminase. (403 aa) |
| | gap | Glyceraldehyde 3-phosphate dehydrogenase; GAPDH. (343 aa) |
| | pgk | Phosphoglycerate kinase. (415 aa) |
| | cobA | uroporphyrin-III C-methyltransferase; SUMT; Belongs to the precorrin methyltransferase family. (249 aa) |
| | mqnD | Conserved hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (284 aa) |
| | APE_0249.1 | Conserved hypothetical protein. (382 aa) |
| | APE_0255.1 | Putative sugar-phosphate nucleotidyl transferase. (250 aa) |
| | APE_0309.1 | Putative oxidoreductase. (367 aa) |
| | APE_0317.1 | Phospho-sugar mutase; Belongs to the phosphohexose mutase family. (464 aa) |
| | APE_0385.1 | acyl-CoA dehydrogenase. (543 aa) |
| | APE_0412 | Hypothetical protein. (362 aa) |
| | loxD | D-lactate dehydrogenase. (473 aa) |
| | pyk | Pyruvate kinase; PK; Belongs to the pyruvate kinase family. (458 aa) |
| | APE_0562.1 | Putative prephenate dehydrogenase. (268 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (380 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (427 aa) |
| | aroK | Shikimate kinase. (280 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (222 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (358 aa) |
| | aroG | Phospho-2-dehydro-3-deoxyheptonate aldolase. (270 aa) |
| | APE_0583 | Putative transketolase C-terminal section. (322 aa) |
| | APE_0586.1 | Putative transketolase N-terminal section. (236 aa) |
| | ppsA | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (820 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (237 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate. Can utilize both NAD and NADP. Catalytic efficiency for malate oxidation is 3-fold higher with NADP. Belongs to the LDH/MDH superfamily. (308 aa) |
| | aspC | Aspartate aminotransferase; Transaminase A. (401 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (274 aa) |
| | panE | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (309 aa) |
| | APE_0683 | Phosphoserine phosphatase. (222 aa) |
| | APE_0689.1 | Isocitrate dehydrogenase [NADP]; NADP-IDH. (432 aa) |
| | menC | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (375 aa) |
| | APE_0739 | acyl-CoA dehydrogenase. (345 aa) |
| | APE_0766 | Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (239 aa) |
| | APE_0768.1 | Bifunctional phosphoglucose / phosphomannose isomerase; Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency; Belongs to the PGI/PMI family. (333 aa) |
| | surE | 5'(3')-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (267 aa) |
| | APE_0912 | Putative dehydrogenase. (260 aa) |
| | APE_0929.1 | Putative 3-ketoacyl-CoA thiolase. (397 aa) |
| | APE_0935 | Hypothetical protein. (337 aa) |
| | sdhB | Succinate dehydrogenase subunit B. (305 aa) |
| | sdhD | Putative succinate dehydrogenase subunit D. (117 aa) |
| | sdhC | Succinate dehydrogenase subunit C. (119 aa) |
| | sdhA | Succinate dehydrogenase subunit A. (583 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (143 aa) |
| | adkA | Adenylate kinase; ATP-AMP transphosphorylase; Belongs to the archaeal adenylate kinase family. (202 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase. (238 aa) |
| | ribC | Riboflavin synthase; Belongs to the DMRL synthase family. (155 aa) |
| | APE_0996.1 | Glycerate kinase. (448 aa) |
| | dapA | Putative dihydrodipicolinate synthase. (303 aa) |
| | sucC | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (378 aa) |
| | sucD | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa) |
| | fbpA | Fructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (387 aa) |
| | lysC | Aspartate kinase; Belongs to the aspartokinase family. (454 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; ASADH. (349 aa) |
| | hom | Homoserine dehydrogenase; HDH. (332 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (187 aa) |
| | rfbD | dTDP-4-dehydrorhamnose reductase; RmlD. (300 aa) |
| | rfbB | dTDP-glucose 4,6-dehydratase; RmlB. (330 aa) |
| | rfbA | Glucose-1-phosphate thymidylyltransferase; RmlA; dTDP-glucose synthase. (355 aa) |
| | sat | Sulfate adenylyltransferase; ATP-sulfurylase; Belongs to the sulfate adenylyltransferase family. (383 aa) |
| | APE_1202.1 | Putative nucleotidyl transferase. (416 aa) |
| | APE_1208.1 | Putative nucleotidyl transferase. (363 aa) |
| | APE_1223.1 | Cystathionine beta-synthase; CBS. (389 aa) |
| | metC | Cystathionine gamma-lyase. (384 aa) |
| | APE_1245.1 | Putative zinc-binding dehydrogenase. (326 aa) |
| | acsA | Acetyl-coenzyme A synthetase. (656 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (147 aa) |
| | uppS | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (219 aa) |
| | aroA-2 | 3-phosphoshikimate 1-carboxyvinyltransferase; 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase. (419 aa) |
| | lysZ | Acetylaminoadipate kinase/acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (270 aa) |
| | lysY | N-acetyl-gamma-aminoadipyl-phosphate reductase/N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (355 aa) |
| | lysJ | Acetyl-lysine aminotransferase/acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (388 aa) |
| | APE_1472 | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. (309 aa) |
| | APE_1473.1 | 2-oxoacid:ferredoxin oxidoreductase alpha subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. (642 aa) |
| | thrC | Threonine synthase. (340 aa) |
| | sirC | Precorrin-2 dehydrogenase. (220 aa) |
| | hemD | Putative uroporphyrinogen-III synthase; UROS. (240 aa) |
| | APE_1498.1 | Threonine dehydratase. (411 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; IMPD. (433 aa) |
| | ino1 | Inositol-3-phosphate synthase. (392 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (223 aa) |
| | APE_1557.1 | Putative alcohol dehydrogenase. (312 aa) |
| | ubiA | 4-hydroxybenzoate octaprenyltransferase. (284 aa) |
| | ubiD | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. (487 aa) |
| | cysK | Cysteine synthase; Cysteine synthase that can also catalyze the synthesis of S- sulfo-L-cysteine from thiosulfate and O(3)-acetyl-L-serine, as well as the sulfhydrylation of L-serine by sulfide. Belongs to the cysteine synthase/cystathionine beta- synthase family. (389 aa) |
| | mat | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (406 aa) |
| | apgM | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (424 aa) |
| | citB | Aconitate hydratase; Aconitase. (903 aa) |
| | ubiX | Probable aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (197 aa) |
| | APE_1652 | PqqE homolog. (389 aa) |
| | APE_1655 | PqqE homolog. (403 aa) |
| | pdhD | Dihydrolipoyl dehydrogenase; Glycine cleavage system L protein; pyruvate dehydrogenase complex, E3 component. (464 aa) |
| | pdhC | Pyruvate dehydrogenase complex, E2 component; Dihydrolipoyllysine-residue acetyltransferase component. (412 aa) |
| | pdhB | Pyruvate dehydrogenase E1 component, beta subunit. (325 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component, alpha subunit. (377 aa) |
| | APE_1681.1 | acyl-CoA dehydrogenase. (389 aa) |
| | APE_1694.1 | Cytochrome AA3 controlling protein. (150 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (375 aa) |
| | gltA | Citrate synthase. (394 aa) |
| | fgs | Farnesylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (332 aa) |
| | fni | Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (375 aa) |
| | APE_1768.1 | Isopentenyl phosphate kinase. (249 aa) |
| | fbpA-2 | Fructose-1,6-bisphosphatase; FBPase; Belongs to the inositol monophosphatase superfamily. (267 aa) |
| | fumC | Fumarate hydratase class II. (444 aa) |
| | gyaR | Glyoxylate reductase. (335 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (309 aa) |
| | hmgA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Converts HMG-CoA to mevalonate. (421 aa) |
| | APE_1872.1 | Putative 3-ketoacyl-CoA thiolase. (377 aa) |
| | APE_1873.1 | HMG-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (361 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (305 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity). (439 aa) |
| | APE_1963.1 | Alcohol dehydrogenase. (390 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (314 aa) |
| | cobD | Threonine-phosphate decarboxylase. (354 aa) |
| | APE_2041.1 | Putative asparagine synthetase. (318 aa) |
| | metE | Methylcobalamin:homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown (By similarity). (332 aa) |
| | APE_2050.1 | Putative methylcobalamin:homocysteine methyltransferase; Putative methionine synthase. (336 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (313 aa) |
| | metB | Cystathionine gamma-synthase. (389 aa) |
| | glk | ATP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ATP as the phosphate donor. ITP can also serve as an effective phosphoryl donor. According to Hansen et al., the enzyme has a broad hexose specificity, and in addition to glucose, which shows the highest catalytic efficiency, it can also phosphorylate fructose, mannose, glucosamine, N-acetylglucosamine, N- acetylmannosamine and 2-deoxyglucose. However, according to Sakuraba et al., the enzyme shows strict specificity for D-glucose. (320 aa) |
| | APE_2094.1 | Conserved hypothetical protein. (197 aa) |
| | APE_2108 | acetyl-CoA acetyltransferase. (402 aa) |
| | gcvPB | Glycine cleavage system P-protein subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (520 aa) |
| | gcvPA | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (465 aa) |
| | APE_2126.1 | 2-oxoacid:ferredoxin oxidoreductase alpha subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate and glyoxylate to form their CoA derivatives. (639 aa) |
| | APE_2128 | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate and glyoxylate to form their CoA derivatives. (318 aa) |
| | hemL | Glutamate-1-semialdehyde aminotransferase; GSA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (430 aa) |
| | APE_2158.1 | acyl-CoA dehydrogenase. (399 aa) |
| | adh | NAD-dependent alcohol dehydrogenase. (344 aa) |
| | aspC-2 | Aspartate aminotransferase; Transaminase A. (405 aa) |
| | APE_2281.1 | Putative cytidylyltransferase. (246 aa) |
| | thrC-2 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (393 aa) |
| | APE_2291 | Putative sugar-phosphate nucleotidyl transferase. (239 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (416 aa) |
| | hemC | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (307 aa) |
| | hemL-2 | Glutamate-1-semialdehyde aminotransferase; GSA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (429 aa) |
| | hemB | Porphobilinogen synthase; ALADH; delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (353 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (449 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (574 aa) |
| | APE_2354 | acyl-CoA dehydrogenase. (405 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (141 aa) |
| | APE_2382.1 | Conserved hypothetical protein. (385 aa) |
| | APE_2384 | Conserved hypothetical protein. (394 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (324 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa) |
| | fabG | 3-oxoacyl-[acyl-carrier-protein] reductase. (250 aa) |
| | APE_2507.1 | Putative glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa) |
| | APE_2509 | Putative acetolactate synthase; Belongs to the TPP enzyme family. (556 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; IGPS; Belongs to the TrpC family. (261 aa) |
| | trpF | N-(5'-phosphoribosyl) anthranilate isomerase; Belongs to the TrpF family. (215 aa) |
| | trpB-2 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (427 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (252 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (345 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (438 aa) |
| | trpG | Anthranilate synthase component II. (196 aa) |
| | acsA-2 | Acetyl-coenzyme A synthetase. (513 aa) |
| | acsA-3 | Acetyl-coenzyme A synthetase. (140 aa) |
