STRINGSTRING
mpl mpl BPSL0657 BPSL0657 BPSL2015 BPSL2015 nagZ nagZ anmK anmK BPSL3046 BPSL3046
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mplUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (494 aa)
BPSL0657Similar to Ralstonia solanacearum hypothetical protein rsc0514 or rs04986 SWALL:Q8Y222 (EMBL:AL646059) (352 aa) fasta scores: E(): 3.9e-76, 59.3% id in 344 aa, and to Pseudomonas aeruginosa hypothetical protein SWALL:Q9X4N9 (EMBL:AF116284) (338 aa) fasta scores: E(): 1.5e-56, 47.23% id in 343 aa. (344 aa)
BPSL2015Putative membrane attached glycosyl hydrolase; Similar to Alteromonas sp. beta-hexosaminidase A precursor Cht60 SWALL:HEXA_ALTSO (SWALL:P48823) (598 aa) fasta scores: E(): 2.1e-59, 35.98% id in 628 aa, and to Ralstonia solanacearum putative hydrolase glycosidase protein rsc0769 or rs05085 SWALL:Q8Y1C1 (EMBL:AL646060) (734 aa) fasta scores: E(): 3.1e-152, 61.84% id in 684 aa; Belongs to the glycosyl hydrolase 3 family. (682 aa)
nagZPutative beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (342 aa)
anmKConserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (403 aa)
BPSL3046Similar to Escherichia coli membrane-bound lytic murein transglycosylase A MltA or Mlt or b2813 or z4130 or ecs3673 SWALL:MLTA_ECOLI (SWALL:P46885) (365 aa) fasta scores: E(): 3e-23, 34.52% id in 307 aa, and to Ralstonia solanacearum putative membrane-bound lytic murein transglycosylase A transmembrane protein Rsc2876 or Rs00226 SWALL:Q8XVF5 (EMBL:AL646072) (380 aa) fasta scores: E(): 3e-78, 59.28% id in 334 aa. (372 aa)
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.