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mnmC mnmC queF queF BPSS0550 BPSS0550 fadH fadH soxG soxG soxA soxA soxD soxD fadH-2 fadH-2 BPSS2268 BPSS2268 BPSL0850 BPSL0850 BPSL1273 BPSL1273 BPSL1645 BPSL1645 BPSL1961 BPSL1961 folD folD BPSL2476 BPSL2476 proC proC metF metF putA putA BPSS0447 BPSS0447
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
mnmCConserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. (684 aa)
queFPutative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). (274 aa)
BPSS0550NADH:flavin oxidoreductase / NADH oxidase family protein; Similar to Rhizobium meliloti probable N-methylproline demethylase StcD or StcD2 or rb1010 or smb21570 SWALL:STCD_RHIME (SWALL:O87278) (678 aa) fasta scores: E(): 2.6e-101, 43.61% id in 681 aa, and to Ralstonia solanacearum probable stachydrine utilization oxidoreductase protein rsp0058 or rs02033 SWALL:Q8XTP8 (EMBL:AL646076) (687 aa) fasta scores: E(): 0, 94.46% id in 687 aa. (687 aa)
fadHSimilar to Escherichia coli 2,4-dienoyl-CoA reductase [NADPH] FadH or b3081 SWALL:FADH_ECOLI (SWALL:P42593) (671 aa) fasta scores: E(): 8.6e-165, 64.33% id in 673 aa, and to Streptomyces coelicolor 2,4-dienoyl-CoA reductase FadH or sco7066 or sc4g1.32 SWALL:Q9FC18 (EMBL:AL939130) (671 aa) fasta scores: E(): 1.8e-183, 71.32% id in 673 aa, and to Pseudomonas aeruginosa 2,4-dienoyl-Coareductase FadH1 or pa3092 SWALL:Q9HZB6 (EMBL:AE004733) (679 aa) fasta scores: E(): 6.1e-177, 68.64% id in 673 aa; possible alternative start site at codon 12. (673 aa)
soxGSimilar to Corynebacterium sp. sarcosine oxidase gamma subunit SoxG SWALL:SOXG_CORS1 (SWALL:Q46338) (203 aa) fasta scores: E(): 1.6e-11, 32.98% id in 191 aa, and to Ralstonia solanacearum probable sarcosine oxidase SoxG2 or rsc1104 or rs04053 SWALL:Q8Y0E0 (EMBL:AL646062) (210 aa) fasta scores: E(): 2.8e-62, 75.71% id in 210 aa, and to Ralstonia solanacearum probable sarcosine oxidase SoxG1 or rsp0049 or rs02024 SWALL:Q8XTQ7 (EMBL:AL646076) (210 aa) fasta scores: E(): 2.8e-59, 73.81% id in 210 aa. (211 aa)
soxASimilar to Corynebacterium sp. sarcosine oxidase alpha subunit SoxA SWALL:SOXA_CORS1 (SWALL:Q46337) (967 aa) fasta scores: E(): 2.3e-145, 46.45% id in 1014 aa, and to Ralstonia solanacearum probable sarcosine oxidase SoxA2 or rsc1103 or rs04054 SWALL:Q8Y0E1 (EMBL:AL646062) (1003 aa) fasta scores: E(): 0, 86.14% id in 1003 aa, and to Pseudomonas aeruginosa sarcosine oxidase alpha subunit SoxA or pa5418 SWALL:Q9HTE6 (EMBL:AE004954) (1005 aa) fasta scores: E(): 1.3e-211, 57.46% id in 1011 aa; Belongs to the GcvT family. (1002 aa)
soxDSimilar to Corynebacterium sp. sarcosine oxidase delta subunit SoxD SWALL:SOXD_CORS1 (SWALL:Q46336) (98 aa) fasta scores: E(): 1.9e-19, 55.81% id in 86 aa, and to Ralstonia solanacearum probable sarcosine oxidase SoxD2 or rsc1102 or rs04055 SWALL:Q8Y0E2 (EMBL:AL646062) (98 aa) fasta scores: E(): 3.4e-31, 76.66% id in 90 aa, and to Ralstonia solanacearum probable sarcosine oxidase SoxD1 or rsp0047 or rs02022 SWALL:Q8XTQ9 (EMBL:AL646076) (107 aa) fasta scores: E(): 6.9e-30, 74.72% id in 91 aa. (96 aa)
fadH-2Similar to Escherichia coli 2,4-dienoyl-CoA reductase [NADPH] FadH or b3081 SWALL:FADH_ECOLI (SWALL:P42593) (671 aa) fasta scores: E(): 3e-151, 60.71% id in 672 aa, and to Pseudomonas aeruginosa 2,4-dienoyl-CoA reductase FadH1 or pa3092 SWALL:Q9HZB6 (EMBL:AE004733) (679 aa) fasta scores: E(): 4.9e-170, 65.73% id in 677 aa. (677 aa)
BPSS2268Putative exported protein; No significant database matches to the full length CDS. C-terminal region is similar to Agrobacterium tumefaciens actinorhodin polyketide dimerase ATU2531 or AGR_C_4599 SWALL:Q8UCF6 (EMBL:AE009199) (179 aa) fasta scores: E(): 1e-13, 37.8% id in 164 aa, and to the C-terminal region of Rhizobium etli probable 4-hydroxyphenylacetate-3-monooxygenase YP049 SWALL:Q8KL32 (EMBL:U80928) (208 aa) fasta scores: E(): 8.8e-17, 40.69% id in 145 aa. Possible alternative translational start site. (157 aa)
BPSL0850Conserved hypothetical protein; Similar to Ralstonia solanacearum putative monooxygenase oxidoreductase protein rsc0763 or rs05090 SWALL:Q8Y1C7 (EMBL:AL646060) (191 aa) fasta scores: E(): 2.6e-42, 66.47% id in 170 aa, and to Agrobacterium tumefaciens nitrilotriacetate monooxygenase atu3277 or agr_l_3083 SWALL:Q8UAU0 (EMBL:AE009257) (175 aa) fasta scores: E(): 1.9e-23, 47.23% id in 163 aa. Similar to the N-terminal region of Chelatobacter heintzii nitrilotriacetate monooxygenase component B NtaB or NmoB SWALL:NTAB_CHEHE (SWALL:P54990) (322 aa) fasta scores: E(): 9.3e-20, 41.21% id in 165 aa. (171 aa)
BPSL1273Putative exported protein; Similar to Pseudomonas aeruginosa hypothetical protein pa0741 SWALL:Q9I5I8 (EMBL:AE004509) (213 aa) fasta scores: E(): 3.7e-28, 46.47% id in 213 aa, and to Agrobacterium tumefaciens hypothetical protein atu1999 or agr_c_3633 SWALL:Q8UDW9 (EMBL:AE009151) (203 aa) fasta scores: E(): 2.1e-26, 48.09% id in 210 aa. (208 aa)
BPSL1645Putative oxygenase; Similar to Agrobacterium tumefaciens nitrilotriacetate monooxygenase component B atu5229 or agr_pat_322 SWALL:Q8UK94 (EMBL:AE008945) (323 aa) fasta scores: E(): 2.9e-40, 41.66% id in 312 aa, and N-terminal region to Chelatobacter heintzii nitrilotriacetate monooxygenase component B NtaB or NmoB SWALL:NTAB_CHEHE (SWALL:P54990) (322 aa) fasta scores: E(): 1.3e-25, 50.58% id in 172 aa. (318 aa)
BPSL1961Putative electron transport protein; Accepts electrons from ETF and reduces ubiquinone. (557 aa)
folDFolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa)
BPSL2476Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (167 aa)
proCPutative pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
metFSimilar to Escherichia coli 5,10-methylenetetrahydrofolate reductase MetF or b3941 SWALL:METF_ECOLI (SWALL:P00394) (296 aa) fasta scores: E(): 1.3e-44, 45.98% id in 274 aa. (276 aa)
putABifunctional PutA protein [includes: proline dehydrogenase (EC 1.5.99.8) (proline oxidase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1309 aa)
BPSS0447Similar to Escherichia coli hypothetical protein YddH or b1462 SWALL:YDDH_ECOLI (SWALL:P76121) (189 aa) fasta scores: E(): 2.5e-22, 38.42% id in 190 aa, and to Xanthomonas campestris hypothetical protein xcc3203 SWALL:AAM42473 (EMBL:AE012437) (193 aa) fasta scores: E(): 6.4e-08, 28.49% id in 179 aa. (201 aa)
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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