STRINGSTRING
BPSS2075 BPSS2075 secE secE BPSL0369 BPSL0369 gshA gshA secD secD secF secF secA secA secY secY
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BPSS2075Conserved hypothetical protein (fragment); Gene remnant. Similar to internal regions of Ralstonia solanacearum probable activation/secretion protein rsc0888 or rs06118 SWALL:Q8Y105 (EMBL:AL646061) (590 aa) fasta scores: E(): 5.1e-05, 55.55% id in 54 aa, and Ralstonia solanacearum probable activation/secretion signal peptide protein rsp0550 or rs06123 SWALL:Q8XSC8 (EMBL:AL646079) (590 aa) fasta scores: E(): 5.9e-05, 64.44% id in 45 aa. (209 aa)
secEPreprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (126 aa)
BPSL0369Similar to Ralstonia solanacearum hypothetical protein rsc0270 or rs03237 SWALL:Q8Y2R5 (EMBL:AL646058) (144 aa) fasta scores: E(): 3.7e-25, 56.37% id in 149 aa, and to Xanthomonas campestris hypothetical protein xcc4159 SWALL:AAM43375 (EMBL:AE012541) (129 aa) fasta scores: E(): 3.1e-14, 48.57% id in 140 aa. (150 aa)
gshAGlutamate--cysteine ligase; Similar to Thiobacillus ferrooxidans glutamate--cysteine ligase GshA SWALL:Q56277 (EMBL:U81808) (436 aa) fasta scores: E(): 3.8e-78, 50.59% id in 419 aa, and to Ralstonia solanacearum hypothetical protein rsc0344 or rs03311 SWALL:Q8Y2J1 (EMBL:AL646058) (431 aa) fasta scores: E(): 2e-125, 71.86% id in 430 aa. (442 aa)
secDPutative protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (674 aa)
secFPutative protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (316 aa)
secAPreprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (931 aa)
secYPreprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (454 aa)
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (14%) [HD]