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pchF pchF macB macB oprM oprM mprA mprA BPSS2304 BPSS2304 BPSS0238 BPSS0238 chrB chrB chrA chrA fliC fliC mrcA mrcA BPSL2104 BPSL2104 amrB amrB oprB oprB bpeA bpeA BPSL0284 BPSL0284 fliF fliF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pchFPyochelin synthetase; Similar to Pseudomonas aeruginosa pyochelin synthetase PchF SWALL:Q9RFM7 (EMBL:AF184622) (1809 aa) fasta scores: E(): 1.1e-173, 56.86% id in 2019 aa. Weakly similar to Yersinia pestis yersiniabactin biosynthetic protein Irp2 or ypo1911 SWALL:Q8ZF24 (EMBL:AJ414150) (2035 aa) fasta scores: E(): 3.8e-91, 29% id in 1958 aa. (2015 aa)
macBMacrolide-specific ABC-type efflux carrier; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (653 aa)
oprMSimilar to Pseudomonas aeruginosa outer membrane protein OprM or OprK SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 5.5e-60, 50.92% id in 487 aa, and to Xanthomonas campestris outer membrane protein xcc2681 SWALL:AAM41953 (EMBL:AE012380) (497 aa) fasta scores: E(): 7e-62, 51.91% id in 495 aa. CDS is extended at the C-terminus in comparison to orthologues. Probable gene fusion resulting from the loss of a stop codon. The effect on the function of CDS is not known. (619 aa)
mprASerine metalloprotease precursor; Previously sequenced as Burkholderia pseudomallei serine metalloprotease precursor SWALL:Q9F881 (EMBL:AF254803) (500 aa) fasta scores: E(): 7.7e-170, 100% id in 500 aa. Similar to Xanthomonas campestris extracellular protease precursor xcc0851 SWALL:EXPR_XANCP (SWALL:P23314) (580 aa) fasta scores: E(): 4.5e-65, 49.02% id in 463 aa. (500 aa)
BPSS2304Penicillin-binding protein; Internal region is similar to an internal region of Escherichia coli penicillin-binding protein 1A MrcA or PonA SWALL:PBPA_ECOLI (SWALL:P02918) (850 aa) fasta scores: E(): 1.4e-21, 30.8% id in 737 aa. C-terminal region is similar to Chlorobium tepidum penicillin-binding protein 1 CT0176 SWALL:AAM71424 (EMBL:AE012797) (763 aa) fasta scores: E(): 1.5e-58, 36.31% id in 771 aa. (839 aa)
BPSS0238Similar to Bacillus subtilis penicillin-binding protein 1A/1B PonA SWALL:PBPA_BACSU (SWALL:P39793) (914 aa) fasta scores: E(): 8.7e-44, 30.94% id in 685 aa, and to Escherichia coli penicillin-binding protein 1B MrcB or PonB or PbpF or b0149 SWALL:PBPB_ECOLI (SWALL:P02919) (844 aa) fasta scores: E(): 9.3e-43, 31.98% id in 591 aa. (720 aa)
chrBChromate resistance exported protein; Similar to Alcaligenes eutrophus protein ChrB SWALL:CHRB_ALCEU (SWALL:P17552) (324 aa) fasta scores: E(): 1.2e-64, 54.66% id in 311 aa, and to Ralstonia solanacearum probable chromate resistance signal peptide protein rsp0554 or rs03925 SWALL:Q8XSC4 (EMBL:AL646079) (323 aa) fasta scores: E(): 9.1e-67, 56.01% id in 316 aa. (331 aa)
chrAChromate resistance transport protein; Highly similar to the plasmid borne Alcaligenes eutrophus chromate transport protein ChrA SWALL:CHRA_ALCEU (SWALL:P17551) (401 aa) fasta scores: E(): 5.6e-109, 75.19% id in 387 aa, and to Ralstonia solanacearum probable chromate transport transmembrane protein rsp0555 or rs03924 SWALL:Q8XSC3 (EMBL:AL646079) (401 aa) fasta scores: E(): 4.1e-110, 74.74% id in 396 aa. (396 aa)
fliCFlagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (388 aa)
mrcASimilar to Escherichia coli penicillin-binding protein 1A MrcA or PonA or b3396 SWALL:PBPA_ECOLI (SWALL:P02918) (850 aa) fasta scores: E(): 1.9e-88, 38.63% id in 818 aa. (773 aa)
BPSL2104Putative penicillin-binding protein; Similar to Ralstonia solanacearum probable penicillin-binding 1 rsc2976 or rs01357 SWALL:Q8XV55 (EMBL:AL646073) (801 aa) fasta scores: E(): 2.2e-183, 61.61% id in 805 aa, and to Neisseria lactamica penicillin-binding protein 1A MrcA or PonA SWALL:PBPA_NEILA (SWALL:O87579) (798 aa) fasta scores: E(): 4.3e-129, 47.4% id in 791 aa. Note: This CDS is longer in its N-terminal region than most of its database matches. (852 aa)
amrBMultidrug efflux system transporter protein AmrB; Almost identical to previously sequenced Burkholderia pseudomallei putative transporter AmrB SWALL:O87936 (EMBL:AF072887) (1043 aa) fasta scores: E(): 0, 99.8% id in 1043 aa. Similar to Escherichia coli acriflavine resistance protein B AcrB or AcrE or b0462 SWALL:ACRB_ECOLI (SWALL:P31224) (1049 aa) fasta scores: E(): 5.5e-199, 51.79% id in 1033 aa. (1043 aa)
oprBSimilar to Pseudomonas aeruginosa outer membrane protein OprM precursor pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 4.1e-85, 55.67% id in 476 aa, and to Xanthomonas axonopodis outer membrane protein xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 5.8e-84, 53.72% id in 497 aa. (514 aa)
bpeASimilar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein A precursor acrA or MtcA or Lir SWALL:ACRA_ECOLI (SWALL:P31223) (397 aa) fasta scores: E(): 5.5e-60, 53.76% id in 385 aa, and to Ralstonia solanacearum probable acriflavin resistance lipoprotein A precursor rsc0011 or rs01833 SWALL:Q8Y3G9 (EMBL:AL646057) (398 aa) fasta scores: E(): 6.6e-61, 55.22% id in 402 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (420 aa)
BPSL0284Putative chromate transport protein; Similar to Ralstonia solanacearum probable transmembrane protein rsc0979 or rs04313 SWALL:Q8Y0R4 (EMBL:AL646062) (193 aa) fasta scores: E(): 9.4e-22, 43.25% id in 178 aa, and to the N-terminal region of Pseudomonas aeruginosa chromate transport protein ChrA SWALL:CHRA_PSEAE (SWALL:P14285) (416 aa) fasta scores: E(): 5e-07, 30.86% id in 162 aa. (199 aa)
fliFFlagellar M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family. (598 aa)
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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