STRINGSTRING
adhC adhC BPSL0665 BPSL0665 glpK glpK plsY plsY BPSL1020 BPSL1020 BPSL1189 BPSL1189 BPSL1401 BPSL1401 BPSL1550 BPSL1550 BPSL1613 BPSL1613 plsX plsX plsC plsC glxK glxK BPSS0260 BPSS0260 BPSS0261 BPSS0261 BPSS1466 BPSS1466 lipA1 lipA1 BPSS2081 BPSS2081 lipA2 lipA2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
adhCNADP-dependent alcohol dehydrogenase; Similar to Mycobacterium tuberculosis, and Mycobacterium bovis NADP-dependent alcohol dehydrogenase AdhC or Adh SWALL:ADH_MYCTU (SWALL:P31975) (346 aa) fasta scores: E(): 3.3e-68, 56% id in 350 aa, and to Xylella fastidiosa NADP-alcohol dehydrogenase XF1136 SWALL:Q9PE92 (EMBL:AE003949) (352 aa) fasta scores: E(): 3.9e-72, 58.48% id in 342 aa. (354 aa)
BPSL0665Similar to Ralstonia solanacearum putative acyltransferase transmembrane protein rsc0522 or rs04959 SWALL:Q8Y215 (EMBL:AL646059) (250 aa) fasta scores: E(): 9.8e-67, 65.59% id in 250 aa, and to Pseudomonas aeruginosa probable acyltransferase pa0005 SWALL:Q9I7C1 (EMBL:AE004440) (257 aa) fasta scores: E(): 6.3e-40, 43.8% id in 242 aa, and to Pseudomonas fluorescens putative N-acylhomoserine lactone synthase HdtS SWALL:Q9F728 (EMBL:AF286536) (259 aa) fasta scores: E(): 3.2e-37, 40.58% id in 239 aa. (259 aa)
glpKPutative glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (500 aa)
plsYPutative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (203 aa)
BPSL1020Similar to Escherichia coli putative aldehyde dehydrogenase AldH or b1300 SWALL:DHAL_ECOLI (SWALL:P23883) (495 aa) fasta scores: E(): 2.3e-61, 41.12% id in 479 aa, and to Ralstonia solanacearum probable aldehyde dehydrogenase oxidoreductase protein rsc2350 or rs01196 SWALL:Q8XWX0 (EMBL:AL646069) (478 aa) fasta scores: E(): 5.1e-138, 73.31% id in 476 aa. (479 aa)
BPSL1189Putative kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (156 aa)
BPSL1401Putative kinase; Similar to Pseudomonas aeruginosa hypothetical protein pa1052 SWALL:Q9I4S2 (EMBL:AE004537) (381 aa) fasta scores: E(): 5.2e-50, 50.13% id in 377 aa, and to Bacillus subtilis glycerate kinase GlxK or S14A SWALL:GRK_BACSU (SWALL:P42100) (382 aa) fasta scores: E(): 1.1e-38, 40.1% id in 379 aa. (387 aa)
BPSL1550Similar to Bacillus subtilis betaine aldehyde dehydrogenase GbsA SWALL:DHAB_BACSU (SWALL:P71016) (490 aa) fasta scores: E(): 1.9e-59, 40.33% id in 476 aa, and to Ralstonia solanacearum putative betaine aldehyde dehydrogenase rsc1456 or rs03851 SWALL:Q8XZE5 (EMBL:AL646064) (478 aa) fasta scores: E(): 1.1e-127, 71.3% id in 474 aa. (478 aa)
BPSL1613Putative glycerol utilisation-related protein; Similar to Agrobacterium tumefaciens 3,4-dihydroxy-2-butanone kinase atu3543 or agr_l_2580 SWALL:Q8UA32 (EMBL:AE009283) (564 aa) fasta scores: E(): 5.5e-112, 60.17% id in 570 aa, and to Lycopersicon esculentum putative 3,4-dihydroxy-2-butanone kinase DhbK SWALL:DHBK_LYCES (SWALL:O04059) (594 aa) fasta scores: E(): 4.6e-59, 43.42% id in 578 aa. (570 aa)
plsXPutative fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (368 aa)
plsCPreviously sequenced as Burkholderia pseudomallei putative 1-acyl-SN-glycerol-3-phosphate acyltransferase PlsC SWALL:O69114 (EMBL:AF064070) (289 aa) fasta scores: E(): 1.5e-111, 100% id in 289 aa. Also highly similar to Neisseria meningitidis 1-acyl-SN-glycerol-3-phosphate acyltransferase Plsc or nmb1294 SWALL:PLSC_NEIMB (SWALL:Q9JZ47) (255 aa) fasta scores: E(): 3.4e-18, 33.88% id in 242 aa. (289 aa)
glxKGlycerate kinase 1; Similar to Escherichia coli glycerate kinase 1 GlxK or GlxB5 or b0514 SWALL:GRK1_ECOLI (SWALL:P77364) (381 aa) fasta scores: E(): 2.6e-63, 55.05% id in 376 aa, and to Xanthomonas axonopodis glycerate kinase xac4360 SWALL:AAM39190 (EMBL:AE012090) (389 aa) fasta scores: E(): 1.6e-77, 64.3% id in 381 aa; Belongs to the glycerate kinase type-1 family. (388 aa)
BPSS0260Putative kinase; Similar to Yersinia pestis putative dihydroxyacetone kinase DhaK or ypo3350 SWALL:Q8ZBQ7 (EMBL:AJ414156) (333 aa) fasta scores: E(): 2.1e-72, 62.72% id in 330 aa, and to Selenomonas ruminantium subsp. ruminantium dihydroxyacetone kinase DhaK1 SWALL:Q93PV9 (EMBL:AF297121) (329 aa) fasta scores: E(): 2.6e-45, 43.3% id in 321 aa. (334 aa)
BPSS0261Putative kinase; Similar to the plasmid-borne Rhizobium meliloti putative dihydroxyacetone kinase protein rb0299 or smb20313 SWALL:Q92WN3 (EMBL:AL603643) (213 aa) fasta scores: E(): 5.6e-36, 54.93% id in 213 aa, and to Selenomonas ruminantium subsp. ruminantium dihydroxyacetone kinase DhaK2 SWALL:Q9F677 (EMBL:AF297121) (207 aa) fasta scores: E(): 1.2e-19, 37.18% id in 199 aa. (219 aa)
BPSS1466Putative aldehyde dehydrogenase family protein; Similar to Streptomyces clavuligerus semialdehyde dehydrogenase Pcd SWALL:O85725 (EMBL:AF073895) (512 aa) fasta scores: E(): 2e-120, 66.05% id in 492 aa, and to Ralstonia solanacearum putative transmembrane aldehyde dehydrogenase oxidoreductase protein rsp1591 or rs02148 SWALL:Q8XPP7 (EMBL:AL646085) (504 aa) fasta scores: E(): 9.4e-134, 69.84% id in 504 aa, and to Rhizobium loti aldehyde dehydrogenase mll2867 SWALL:Q98HH4 (EMBL:AP003000) (504 aa) fasta scores: E(): 4.1e-132, 68.93% id in 499 aa. (503 aa)
lipA1Lipase precursor; Similar to Burkholderia cepacia lipase precursor LipA SWALL:LIP_BURCE (SWALL:P22088) (364 aa) fasta scores: E(): 7.1e-111, 84.34% id in 364 aa, and to Pseudomonas sp. Lipase precursor Lip SWALL:LIP_PSES5 (SWALL:P25275) (364 aa) fasta scores: E(): 4.2e-110, 83.79% id in 364 aa. (364 aa)
BPSS2081Similar to Escherichia coli alpha-galactosidase RafA SWALL:RAFA_ECOLI (SWALL:P16551) (708 aa) fasta scores: E(): 2.3e-105, 39.97% id in 718 aa, and to Yersinia pestis alpha-galactosidase ypo1581 SWALL:Q8ZFU7 (EMBL:AJ414149) (708 aa) fasta scores: E(): 3.6e-108, 40.16% id in 712 aa. (723 aa)
lipA2Lipase precursor; Similar to Burkholderia cepacia lipase precursor LipA SWALL:LIP_BURCE (SWALL:P22088) (364 aa) fasta scores: E(): 2.1e-83, 65.65% id in 364 aa, and to Pseudomonas sp. lipase precursor Lip SWALL:LIP_PSES5 (SWALL:P25275) (364 aa) fasta scores: E(): 5.4e-84, 66.2% id in 364 aa. Similar to BPSS1741, 67.397% identity (70.690% ungapped) in 365 aa overlap. (356 aa)
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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