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plcN2 plcN2 gpsA gpsA clsB clsB BPSL0665 BPSL0665 glpD glpD plsY plsY BPSL1189 BPSL1189 psd psd BPSL1200 BPSL1200 BPSL1876 BPSL1876 BPSL2154 BPSL2154 clsA clsA plcN plcN BPSL2419 BPSL2419 BPSL2525 BPSL2525 plsC plsC BPSL2712 BPSL2712 BPSL2961 BPSL2961 BPSL3066 BPSL3066 ugpQ ugpQ eutC eutC eutB eutB BPSS0067 BPSS0067 BPSS1312 BPSS1312 BPSS1883 BPSS1883 BPSS2261 BPSS2261
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
plcN2Similar to Pseudomonas aeruginosa non-hemolytic phospholipase C precursor PlcN SWALL:PHLN_PSEAE (SWALL:P15713) (692 aa) fasta scores: E(): 2.5e-77, 48.87% id in 708 aa, and to Burkholderia pseudomallei non-hemolytic phospholipase C precursor PlcN SWALL:PHLN_BURPS (SWALL:Q9RGS8) (700 aa) fasta scores: E(): 2.2e-128, 52.84% id in 721 aa. Similar to BPSL2403, 52.705% identity (56.632% ungapped) in 721 aa overlap. (705 aa)
gpsASimilar to Bacillus subtilis glycerol-3-phosphate dehydrogenase [NAD(P)+] GpsA or GlyC SWALL:GPDA_BACSU (SWALL:P46919) (345 aa) fasta scores: E(): 9.9e-39, 42.26% id in 336 aa, and to Ralstonia solanacearum glycerol-3-phosphate dehydrogenase [NAD(P)+] rsc0357 or rs03324 SWALL:GPDA_RALSO (SWALL:Q8Y2H9) (338 aa) fasta scores: E(): 1.2e-79, 68.24% id in 337 aa; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (332 aa)
clsBPutative phospholipase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (424 aa)
BPSL0665Similar to Ralstonia solanacearum putative acyltransferase transmembrane protein rsc0522 or rs04959 SWALL:Q8Y215 (EMBL:AL646059) (250 aa) fasta scores: E(): 9.8e-67, 65.59% id in 250 aa, and to Pseudomonas aeruginosa probable acyltransferase pa0005 SWALL:Q9I7C1 (EMBL:AE004440) (257 aa) fasta scores: E(): 6.3e-40, 43.8% id in 242 aa, and to Pseudomonas fluorescens putative N-acylhomoserine lactone synthase HdtS SWALL:Q9F728 (EMBL:AF286536) (259 aa) fasta scores: E(): 3.2e-37, 40.58% id in 239 aa. (259 aa)
glpDSimilar to Pseudomonas aeruginosa glycerol-3-phosphate dehydrogenase GlpD or pa3584 SWALL:GLPD_PSEAE (SWALL:P52111) (512 aa) fasta scores: E(): 9.6e-105, 57.91% id in 480 aa, and to Xanthomonas axonopodis glycerol-3-phosphate dehydrogenase GlpD or xac0360 SWALL:AAM35252 (EMBL:AE011662) (501 aa) fasta scores: E(): 5.5e-117, 63.25% id in 479 aa, and to Xanthomonas campestris glycerol-3-phosphate dehydrogenase GlpD or xcc0360 SWALL:AAM39679 (EMBL:AE012132) (508 aa) fasta scores: E(): 5.5e-116, 61.38% id in 505 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (510 aa)
plsYPutative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (203 aa)
BPSL1189Putative kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (156 aa)
psdPutative decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (216 aa)
BPSL1200Similar to Ralstonia solanacearum putative CDP-diacylglycerol--serine O-phosphatidyltransferase protein PssA or rsc2073 or rs03638 SWALL:Q8XXP0 (EMBL:AL646068) (291 aa) fasta scores: E(): 3.3e-79, 71.67% id in 286 aa, and to Helicobacter pylori CDP-diacylglycerol--serine O-phosphatidyltransferase PssA or Ptr or hp1071 SWALL:PSS_HELPY (SWALL:Q48269) (237 aa) fasta scores: E(): 2.9e-23, 35.14% id in 239 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (290 aa)
BPSL1876Similar to Arabidopsis thaliana putative phospholipase t12j13.18 or t21p5.4 SWALL:Q9S816 (EMBL:AC009327) (521 aa) fasta scores: E(): 3.4e-32, 30.87% id in 502 aa, and to Sulfolobus solfataricus acid phosphatase, putative sso2789 SWALL:Q97V43 (EMBL:AE006873) (511 aa) fasta scores: E(): 5.1e-08, 25.63% id in 476 aa. (506 aa)
BPSL2154Putative phosphatidate cytidylyltransferase membrane protein; Similar to Escherichia coli, and Escherichia coli O157:H7 phosphatidate cytidylyltransferase CdsA or Cds or b0175 or z0186 or ecs0177 SWALL:CDSA_ECOLI (SWALL:P06466) (249 aa) fasta scores: E(): 9.8e-07, 36.18% id in 257 aa, and to Ralstonia solanacearum probable phosphatidate cytidylyltransferase transmembrane protein rsc1409 or rs05283 SWALL:Q8XZI6 (EMBL:AL646064) (271 aa) fasta scores: E(): 1.5e-42, 54.15% id in 277 aa; Belongs to the CDS family. (273 aa)
clsAPutative cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (479 aa)
plcNHypothetical protein (pseudogene); Hydrolyzes phosphatidylserine as well as phosphatidylcholine. (700 aa)
BPSL2419Similar to Escherichia coli, and Escherichia coli O157:H7 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA SWALL:PGSA_ECOLI (SWALL:P06978) (181 aa) fasta scores: E(): 7.9e-28, 48.38% id in 186 aa, and to Ralstonia solanacearum probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase transmembrane protein rsc1072 or rs04115 SWALL:Q8Y0H2 (EMBL:AL646062) (191 aa) fasta scores: E(): 1.7e-56, 73.05% id in 193 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (197 aa)
BPSL2525Conserved hypothetical protein; Similar to several including: Rhizobium loti hypothetical protein Mlr5374 SWALL:Q98BY6 (EMBL:AP003006) (199 aa) fasta scores: E(): 9.8e-26, 47.36% id in 190 aa and to Bradyrhizobium japonicum pPmtA protein pmtA SWALL:Q9LCT2 (EMBL:Y09633) (199 aa) fasta scores: E(): 9.8e-20, 42.28% id in 201 aa. (228 aa)
plsCPreviously sequenced as Burkholderia pseudomallei putative 1-acyl-SN-glycerol-3-phosphate acyltransferase PlsC SWALL:O69114 (EMBL:AF064070) (289 aa) fasta scores: E(): 1.5e-111, 100% id in 289 aa. Also highly similar to Neisseria meningitidis 1-acyl-SN-glycerol-3-phosphate acyltransferase Plsc or nmb1294 SWALL:PLSC_NEIMB (SWALL:Q9JZ47) (255 aa) fasta scores: E(): 3.4e-18, 33.88% id in 242 aa. (289 aa)
BPSL2712Putative hydrolase; Similar to Ralstonia solanacearum putative glycerophosphoryl diester phosphodiesterase, periplasmic precursor protein GlpQ or rsc0502 or rs05020 SWALL:Q8Y234 (EMBL:AL646059) (378 aa) fasta scores: E(): 4.4e-95, 68.66% id in 383 aa, and to Xanthomonas campestris glycerophosphoryl diester phosphodiesterase GlpQ or xcc4234 SWALL:AAM43450 (EMBL:AE012551) (370 aa) fasta scores: E(): 1.5e-65, 55.75% id in 339 aa. (378 aa)
BPSL2961Putative phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (157 aa)
BPSL3066Putative hydrolase; Similar to Pseudomonas aeruginosa hypothetical protein Pa4792 SWALL:Q9HV16 (EMBL:AE004892) (311 aa) fasta scores: E(): 2.8e-46, 49.02% id in 308 aa, and to Bacillus subtilis glycerophosphoryl diester phosphodiesterase GlpQ SWALL:GLPQ_BACSU (SWALL:P37965) (293 aa) fasta scores: E(): 0.00032, 30.82% id in 133 aa. (326 aa)
ugpQSimilar to Escherichia coli glycerophosphoryl diester phosphodiesterase UgpQ or b3449 SWALL:UGPQ_ECOLI (SWALL:P10908) (247 aa) fasta scores: E(): 7.7e-54, 58.36% id in 245 aa. (253 aa)
eutCSimilar to Salmonella typhimurium ethanolamine ammonia-lyase light chain EutC or Stm2457 SWALL:EUTC_SALTY (SWALL:P19265) (298 aa) fasta scores: E(): 9.2e-18, 38.42% id in 216 aa, and to Ralstonia solanacearum ethanolamine ammonia-lyase light chain EutC or Rsc3126 or Rs00477 SWALL:Q8XUR0 (EMBL:AL646073) (270 aa) fasta scores: E(): 9.8e-46, 55.64% id in 257 aa; Belongs to the EutC family. (267 aa)
eutBSimilar to Salmonella typhimurium ethanolamine ammonia-lyase heavy chain EutB or Stm2458 SWALL:EUTB_SALTY (SWALL:P19264) (453 aa) fasta scores: E(): 3.2e-85, 52.24% id in 446 aa. (465 aa)
BPSS0067Similar to Pseudomonas aeruginosa non-hemolytic phospholipase C precursor PlcN or pa3319 SWALL:PHLN_PSEAE (SWALL:P15713) (692 aa) fasta scores: E(): 6e-54, 53.29% id in 728 aa, and to Burkholderia pseudomallei non-hemolytic phospholipase C precursor PlcN SWALL:PHLN_BURPS (SWALL:Q9RGS8) (700 aa) fasta scores: E(): 4e-39, 45.43% id in 744 aa. (731 aa)
BPSS1312Hypothetical protein; Similar to the N-terminal regions of Arabidopsis thaliana hypothetical 59.0 kDa protein at3g03520 SWALL:Q8VZ53 (EMBL:AY065242) (523 aa) fasta scores: E(): 4.6e-40, 35.03% id in 471 aa, and to Arabidopsis thaliana t21p5.6 protein t21p5.6 or at3g03520 SWALL:Q9SRQ6 (EMBL:AC009895) (523 aa) fasta scores: E(): 4.6e-40, 35.03% id in 471 aa. (486 aa)
BPSS1883Conserved hypothetical protein; Similar to Xanthomonas axonopodis cardiolipin synthase Cls or xac2871 SWALL:AAM37716 (EMBL:AE011929) (520 aa) fasta scores: E(): 1.5e-61, 41.13% id in 530 aa, and to Pseudomonas aeruginosa hypothetical protein pa5310 SWALL:Q9HTP4 (EMBL:AE004943) (529 aa) fasta scores: E(): 1.7e-61, 40.15% id in 528 aa. (550 aa)
BPSS2261Putative phosphatidylserine decarboxylase; No significant database matches to the full length CDS. C-terminus is similar to the C-terminal region of Schizosaccharomyces pombe phosphatidylserine decarboxylase proenzyme 2 precursor SPAC31G5.15 SWALL:O14111 (EMBL:Z98979) (980 aa) fasta scores: E(): 4.9e-09, 33.33% id in 204 aa. (433 aa)
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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