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BPSL0843 BPSL0843 BPSS1791 BPSS1791 mhpE mhpE mhpF mhpF benA benA benB benB benC benC benD benD
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BPSL0843Aldehyde dehydrogenase family protein; Similar to previously sequenced Burkholderia sp. RP007 dehydrogenase PhnF SWALL:Q9ZHH7 (EMBL:AF061751) (483 aa) fasta scores: E(): 1.1e-103, 61.41% id in 482 aa. Similar to Rhizobium loti dehydrogenase mll7197 SWALL:Q986V2 (EMBL:AP003011) (481 aa) fasta scores: E(): 1.7e-114, 66.73% id in 481 aa, and to Ralstonia solanacearum probable vanillin dehydrogenase oxidoreductase protein Vdh or rsp0226 or rs05197 SWALL:Q8XT89 (EMBL:AL646077) (484 aa) fasta scores: E(): 2.7e-111, 65.63% id in 483 aa; Alternative start site at codon 11; Belongs to the aldeh [...] (483 aa)
BPSS1791Similar to Streptomyces coelicolor hypothetical protein sco1037 or scg20a.17 SWALL:Q9K3M3 (EMBL:AL939107) (133 aa) fasta scores: E(): 4.5e-12, 40.62% id in 128 aa, and to Bacillus subtilis hypothetical protein YrdN SWALL:YRDN_BACSU (SWALL:P94502) (129 aa) fasta scores: E(): 4.6e-11, 34.64% id in 127 aa. (127 aa)
mhpE4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (347 aa)
mhpFAcetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (297 aa)
benASimilar to Acinetobacter calcoaceticus benzoate 1,2-dioxygenase alpha subunit BenA SWALL:BENA_ACICA (SWALL:P07769) (461 aa) fasta scores: E(): 2.6e-150, 74.65% id in 438 aa, and to Pseudomonas putida benzoate 1,2-dioxygenase large subunit BenA SWALL:Q93SR8 (EMBL:AY026914) (455 aa) fasta scores: E(): 1.8e-142, 73.68% id in 437 aa. (455 aa)
benBSimilar to Acinetobacter calcoaceticus benzoate 1,2-dioxygenase beta subunit BenB SWALL:BENB_ACICA (SWALL:P07770) (169 aa) fasta scores: E(): 1.8e-48, 71.16% id in 163 aa, and to Pseudomonas putida benzoate 1,2-dioxygenase small subunit BenB SWALL:Q93SR7 (EMBL:AY026914) (162 aa) fasta scores: E(): 1.3e-42, 66.45% id in 155 aa. (163 aa)
benCSimilar to Acinetobacter calcoaceticus benzoate 1,2-dioxygenase electron transfer component [includes: ferredoxin; ferredoxin--NAD(+) reductase (EC 1.18.1.3)] BenC SWALL:BENC_ACICA (SWALL:P07771) (348 aa) fasta scores: E(): 3.8e-77, 61.49% id in 335 aa, and to Pseudomonas putida benzoate dioxygenase-ferredoxin reductase BenC SWALL:Q9L7Y3 (EMBL:AF218267) (336 aa) fasta scores: E(): 2.4e-69, 56.25% id in 336 aa. (339 aa)
benDSimilar to Acinetobacter calcoaceticus cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase BenD SWALL:BEND_ACICA (SWALL:P07772) (261 aa) fasta scores: E(): 1.3e-60, 64.45% id in 256 aa, and to Pseudomonas putida cis-diol dehydrogenase BenD SWALL:Q9L7Y2 (EMBL:AF218267) (253 aa) fasta scores: E(): 2.6e-61, 67.57% id in 256 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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