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pgk pgk cbbA cbbA ppc ppc tpiA tpiA rpiA rpiA BPSL2222 BPSL2222 BPSL2223 BPSL2223 fbp fbp gapA gapA tktA tktA maeB maeB BPSL3048 BPSL3048 BPSL3242 BPSL3242 BPSS0254 BPSS0254 mdh mdh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pgkSimilar to Escherichia coli phosphoglycerate kinase Pgk or b2926 SWALL:PGK_ECOLI (SWALL:P11665) (386 aa) fasta scores: E(): 1.8e-80, 63.7% id in 394 aa, and to Ralstonia solanacearum phosphoglycerate kinase Pgk or rsc0571 or rs04894 SWALL:Q8Y1W6 (EMBL:AL646060) (419 aa) fasta scores: E(): 1.7e-115, 85.64% id in 397 aa. (397 aa)
cbbAFructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (994 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (231 aa)
BPSL2222Putative transketolase; Similar to Thermoplasma acidophilum probable transketolase ta0617 SWALL:Q9HKI2 (EMBL:AL445064) (316 aa) fasta scores: E(): 2.6e-24, 32.67% id in 303 aa, and to Pyrococcus abyssi transketolase C-terminal section Tkt2 or pab0296 SWALL:Q9V1I1 (EMBL:AJ248284) (317 aa) fasta scores: E(): 9.6e-22, 32.65% id in 294 aa. (303 aa)
BPSL2223Putative transketolase; Similar to Fusobacterium nucleatum transketolase subunit A fn0294 SWALL:Q8RGJ9 (EMBL:AE010542) (270 aa) fasta scores: E(): 2.2e-33, 42.53% id in 268 aa, and to Methanococcus jannaschii putative transketolase N-terminal section mj0681 SWALL:TKTN_METJA (SWALL:Q58094) (274 aa) fasta scores: E(): 2.5e-29, 38.62% id in 277 aa. (279 aa)
fbpSimilar to Alcaligenes eutrophus fructose-1,6-bisphosphatase, chromosomal CbbfC or cfxF SWALL:F16P_ALCEU (SWALL:P19911) (364 aa) fasta scores: E(): 1.2e-79, 60.41% id in 341 aa, and to Pseudomonas aeruginosa fructose-1,6-bisphosphatase Fbp or pa5110 SWALL:Q9HU73 (EMBL:AE004923) (336 aa) fasta scores: E(): 4.9e-96, 72.23% id in 335 aa. (338 aa)
gapASimilar to Bacillus subtilis glyceraldehyde 3-phosphate dehydrogenase 1 AapA or Gap SWALL:G3P1_BACSU (SWALL:P09124) (334 aa) fasta scores: E(): 2.7e-71, 60.06% id in 333 aa, and to Alcaligenes eutrophus glyceraldehyde 3-phosphate dehydrogenase, plasmid CbbGP SWALL:G3PP_ALCEU (SWALL:P50322) (336 aa) fasta scores: E(): 5.1e-112, 84.52% id in 336 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
tktATransketolase 1; Similar to Escherichia coli transketolase 1 TktA or Tkt or b2935 SWALL:TKT1_ECOLI (SWALL:P27302) (663 aa) fasta scores: E(): 4.8e-167, 63.48% id in 671 aa, and to Ralstonia solanacearum probable transketolase protein rsc2750 or rs00104 SWALL:Q8XVS9 (EMBL:AL646071) (675 aa) fasta scores: E(): 4.5e-192, 72.99% id in 674 aa; Belongs to the transketolase family. (675 aa)
maeBSimilar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 5.4e-181, 61.8% id in 754 aa, and to Ralstonia solanacearum putative NADP-dependent malic enzyme oxidoreductase protein rsc2767 or rs00080 SWALL:Q8XVR2 (EMBL:AL646071) (781 aa) fasta scores: E(): 0, 78.28% id in 760 aa. (769 aa)
BPSL3048Similar to Alcaligenes eutrophus ribulose-phosphate 3-epimerase, plasmid CbbEP or CfxE SWALL:RPEP_ALCEU (SWALL:Q04539) (241 aa) fasta scores: E(): 9.3e-62, 70.71% id in 239 aa. (243 aa)
BPSL3242Similar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 1.6e-184, 63.72% id in 758 aa, and to Ralstonia solanacearum putative NADP-dependent malic enzyme oxidoreductase protein MaeB1 or Rsc2123 or Rs03232 SWALL:Q8XXJ0 (EMBL:AL646068) (773 aa) fasta scores: E(): 5.7e-194, 67.86% id in 753 aa; Belongs to the malic enzymes family. (756 aa)
BPSS0254Similar to Escherichia coli ribose 5-phosphate isomerase B RpiB or b4090 SWALL:RPIB_ECOLI (SWALL:P37351) (149 aa) fasta scores: E(): 5.9e-21, 46.62% id in 148 aa, and to Yersinia pestis ribose 5-phosphate isomerase B RpiB or ypo3353 or y0837 SWALL:AAM84422 (EMBL:AJ414156) (151 aa) fasta scores: E(): 1.7e-28, 55.4% id in 148 aa. (164 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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