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BPSL0461 BPSL0461 ctaB ctaB BPSL0961 BPSL0961 BPSL0962 BPSL0962 cobT cobT cobS cobS BPSL0981 BPSL0981 cobC cobC cobD cobD BPSL0986 BPSL0986 cobQ cobQ hemC hemC BPSL1016 BPSL1016 hemF hemF cobM cobM cobK cobK cbiD cbiD cobL cobL BPSL1759 BPSL1759 cobH cobH cobI cobI cobJ cobJ BPSL1767 BPSL1767 CobN CobN BPSL1771 BPSL1771 cobO cobO cobB cobB gltX gltX BPSL2366 BPSL2366 cobD-2 cobD-2 hemL hemL hemH hemH BPSL2841 BPSL2841 BPSL2934 BPSL2934 hemA hemA hemB hemB hemE hemE bfr bfr BPSS1245 BPSS1245 BPSS1278 BPSS1278 BPSS2171 BPSS2171
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second shell of interactors
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proteins of unknown 3D structure
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BPSL0461Putative cytochrome oxidase assembly protein; Similar to Ralstonia solanacearum putative heme O oxygenase CtaA SWALL:Q8Y2G5 (EMBL:AL646058) (363 aa) fasta scores: E(): 4.5e-83, 63.63% id in 330 aa, and to Pseudomonas aeruginosa hypothetical protein pa0112 SWALL:Q9I720 (EMBL:AE004449) (357 aa) fasta scores: E(): 1.1e-50, 45.59% id in 329 aa. (349 aa)
ctaBUbiA prenyltransferase family protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (300 aa)
BPSL0961Similar to Paracoccus denitrificans uroporphyrin-III C-methyltransferase NirE SWALL:NIRE_PARDE (SWALL:Q51701) (287 aa) fasta scores: E(): 1.3e-24, 43.75% id in 256 aa, and to the C-terminal region of Escherichia coli, and Escherichia coli O157:H7 siroheme synthase [includes: uroporphyrin-iii c-methyltransferase; precorrin-2 oxidase; ferrochelatase] CysG or b3368 or z4729 or ecs4219 SWALL:CYSG_ECOLI (SWALL:P11098) (457 aa) fasta scores: E(): 4.3e-23, 41.35% id in 237 aa. (278 aa)
BPSL0962Similar to Ralstonia solanacearum hypothetical protein rsc2418 or rs02695 SWALL:Q8XWQ5 (EMBL:AL646070) (123 aa) fasta scores: E(): 8.2e-27, 64.46% id in 121 aa. (128 aa)
cobTPutative nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (352 aa)
cobSPutative cobalamin [5'-phosphate] synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (252 aa)
BPSL0981Phosphoglycerate mutase family; Similar to Ralstonia solanacearum hypothetical protein rsc2395 or rs02727 SWALL:Q8XWS5 (EMBL:AL646069) (192 aa) fasta scores: E(): 1.3e-22, 43.09% id in 181 aa, and to Rhodobacter capsulatus BluF protein SWALL:O68088 (EMBL:AF010496) (195 aa) fasta scores: E(): 2.5e-06, 38.33% id in 180 aa, and to Escherichia coli alpha-ribazole-5'-phosphate phosphatase CobC or PhpB or b0638 SWALL:COBC_ECOLI (SWALL:P52086) (203 aa) fasta scores: E(): 7.1e-05, 29.94% id in 187 aa. (199 aa)
cobCPutative cobalamin biosynthesis aminotransferase protein; Similar to Pseudomonas denitrificans CobC protein SWALL:COBC_PSEDE (SWALL:P21633) (333 aa) fasta scores: E(): 2.2e-31, 43.06% id in 339 aa, and to Ralstonia solanacearum probable cobalamin biosynthesis protein pyridoxal-phosphate-dependent aminotransferase rsc2393 or rs02729 SWALL:Q8XWS7 (EMBL:AL646069) (350 aa) fasta scores: E(): 2.5e-62, 57.18% id in 341 aa, and to Xanthomonas axonopodis cobalamin biosynthetic protein xac3189 SWALL:AAM38033 (EMBL:AE011964) (327 aa) fasta scores: E(): 1.7e-49, 51.07% id in 327 aa. (350 aa)
cobDPutative cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (314 aa)
BPSL0986Putative bifunctional cobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (185 aa)
cobQPutative cobyric acid synthase protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (486 aa)
hemCPutative porphobilinogen deaminase protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (329 aa)
BPSL1016Full length similar to Ralstonia solanacearum probable bifunctional: uroporphyrin-III C-methyltransferase and uroporphyrinogen-III synthase transmembrane protein rsc2356 or rs01190 SWALL:Q8XWW4 (EMBL:AL646069) (695 aa) fasta scores: E(): 1.8e-32, 39.35% id in 681 aa, and N-terminal region similar to Pseudomonas aeruginosa uroporphyrinogen-III synthase HemD or pa5259 SWALL:HEM4_PSEAE (SWALL:P48246) (251 aa) fasta scores: E(): 0.0084, 36.8% id in 269 aa, and C-terminal region to Escherichia coli putative uroporphyrin-III C-methyltransferase HemX or b3803 SWALL:HEMX_ECOLI (SWALL:P09127) ( [...] (660 aa)
hemFCoproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (307 aa)
cobMSimilar to Rhodococcus erythropolis precorrin-4 C11-methyltransferase CobM SWALL:COBM_RHOER (SWALL:Q53138) (249 aa) fasta scores: E(): 3.3e-43, 52.69% id in 241 aa, and to Pseudomonas denitrificans precorrin-4 C11-methyltransferase CobM SWALL:COBM_PSEDE (SWALL:P21922) (253 aa) fasta scores: E(): 1.1e-41, 52.43% id in 246 aa. (241 aa)
cobKSimilar to Rhodococcus erythropolis precorrin-6X reductase CobK SWALL:COBK_RHOER (SWALL:Q53139) (248 aa) fasta scores: E(): 1.2e-30, 45.56% id in 248 aa, and to Streptomyces coelicolor putative precorrin-6X reductase sco3283 or sce39.33C SWALL:Q9X8F6 (EMBL:AL049573) (255 aa) fasta scores: E(): 5.9e-32, 48.81% id in 252 aa. (242 aa)
cbiDPutative cobalamin biosynthesis-related protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (363 aa)
cobLSimilar to Pseudomonas denitrificans precorrin-6Y C5,15-methyltransferase [decarboxylating] cobL SWALL:COBL_PSEDE (SWALL:P21921) (413 aa) fasta scores: E(): 7.9e-67, 49.62% id in 401 aa, and to Brucella melitensis precorrin-6Y C5,15-methyltransferase bmei0716 SWALL:Q8YHT0 (EMBL:AE009513) (401 aa) fasta scores: E(): 1.9e-90, 61.71% id in 397 aa. (408 aa)
BPSL1759Putative oxidoreductase; Similar to Pseudomonas aeruginosa probable oxidoreductase pa2906 SWALL:Q9HZU1 (EMBL:AE004716) (486 aa) fasta scores: E(): 2.4e-32, 50.53% id in 465 aa, and to Physcomitrella patens ferredoxin-nitrite reductase Nii1 SWALL:BAB92078 (EMBL:AB074427) (602 aa) fasta scores: E(): 8.9e-13, 27.57% id in 417 aa. Note : This CDS has most of its database hits to eukaryotic entries. (482 aa)
cobHSimilar to Pseudomonas denitrificans precorrin-8X methylmutase CobH SWALL:COBH_PSEDE (SWALL:P21638) (210 aa) fasta scores: E(): 3.7e-44, 66.33% id in 202 aa, and to Brucella melitensis precorrin-8X methylmutase bmei0714 SWALL:Q8YHT2 (EMBL:AE009513) (208 aa) fasta scores: E(): 3.5e-55, 75.48% id in 208 aa. (208 aa)
cobIPrecorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. (244 aa)
cobJSimilar to Pseudomonas denitrificans precorrin-3b C17-methyltransferase CobJ SWALL:COBJ_PSEDE (SWALL:P21640) (254 aa) fasta scores: E(): 1.1e-35, 52.2% id in 249 aa, and to C-terminal region to Mycobacterium tuberculosis cobalamin biosynthesis protein rv2066 or mt2126 or mtcy49.05 SWALL:COBI_MYCTU (SWALL:Q10677) (508 aa) fasta scores: E(): 1.8e-31, 40% id in 365 aa. (616 aa)
BPSL1767C-terminal region is similar to Pseudomonas putida magnesium chelatase, subunit CHII PP3506 SWALL:Q88H59 (EMBL:AE016787) (337 aa) fasta scores: E(): 1.9e-40, 53.43% id in 335 aa. Full length CDS is similar to Chromobacterium violaceum probable chelatase protein CV1570 SWALL:Q7NXQ6 (EMBL:AE016915) (635 aa) fasta scores: E(): 2.8e-28, 44.29% id in 438 aa. (408 aa)
CobNPutative cobalamin biosynthesis-related protein; Similar to Pseudomonas denitrificans CobN protein SWALL:COBN_PSEDE (SWALL:P29929) (1275 aa) fasta scores: E(): 2.5e-110, 48.16% id in 1306 aa, and to Rhizobium meliloti probable cobalamin biosynthesis protein r01957 or smc04303 SWALL:Q92P36 (EMBL:AL591789) (1275 aa) fasta scores: E(): 1.4e-106, 48.42% id in 1305 aa. (1281 aa)
BPSL1771Putative cobalamin biosynthesis related protein; Similar to C-terminal region of Ralstonia solanacearum putative precorrin methylase protein CbiG or rsp0619 or rs03748 SWALL:Q8XS62 (EMBL:AL646079) (254 aa) fasta scores: E(): 4.8e-06, 46.85% id in 143 aa, and to Pseudomonas denitrificans CobE protein SWALL:COBE_PSEDE (SWALL:P21635) (154 aa) fasta scores: E(): 0.36, 31.97% id in 147 aa. Possible gene remnant. (150 aa)
cobOCobalamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (200 aa)
cobBSimilar to Pseudomonas aeruginosa cobyrinic acid A,C-diamide synthase CobB or pa1273 SWALL:COBB_PSEAE (SWALL:Q9I471) (435 aa) fasta scores: E(): 2.8e-48, 49.81% id in 528 aa, and to Bacillus megaterium cobyrinic acid A,C-diamide synthase CobB or CbiA SWALL:COBB_BACME (SWALL:O87698) (460 aa) fasta scores: E(): 4.4e-16, 29.29% id in 536 aa. Note: This CDS contains an unique region from approximately residue 225 to approximately residue 340 that has no similarity to any of the database matches. (535 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (469 aa)
BPSL2366Similar to Escherichia coli oxygen-independent coproporphyrinogen III oxidase HemN SWALL:HEMN_ECOLI (SWALL:P32131) (457 aa) fasta scores: E(): 3.3e-80, 47.34% id in 452 aa, and to Neisseria meningitidis oxygen-independent coproporphyrinogen III oxidase nma2108 SWALL:Q9JSW2 (EMBL:AL162758) (473 aa) fasta scores: E(): 3.6e-91, 49.56% id in 456 aa. Possible alternative translational start site; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (481 aa)
cobD-2Putative membrane protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (329 aa)
hemLSimilar to Neisseria meningitidis glutamate-1-semialdehyde 2,1-aminomutase HemL or nmb1864 SWALL:GSA_NEIMB (SWALL:Q9JXW0) (427 aa) fasta scores: E(): 3.2e-104, 66.82% id in 425 aa, and to Ralstonia solanacearum probable glutamate-1-semialdehyde 2,1-aminomutase protein HemL or rsc0666 or rs01571 SWALL:Q8Y1M4 (EMBL:AL646060) (433 aa) fasta scores: E(): 7.7e-118, 76.69% id in 429 aa. (427 aa)
hemHPutative ferrochelatase protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (367 aa)
BPSL2841Similar to Ralstonia solanacearum hypothetical protein rsc2663 or rs04544 SWALL:Q8XW12 (EMBL:AL646071) (185 aa) fasta scores: E(): 4.8e-55, 80.11% id in 181 aa, and to Xanthomonas campestris hypothetical protein Xcc0796 SWALL:AAM40111 (EMBL:AE012179) (185 aa) fasta scores: E(): 2.8e-38, 60% id in 185 aa, and to Xanthomonas axonopodis hypothetical protein Xac0870 SWALL:AAM35758 (EMBL:AE011718) (185 aa) fasta scores: E(): 1.6e-36, 57.83% id in 185 aa; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
BPSL2934Putative membrane protein; Similar to Ralstonia solanacearum probable transmembrane protein rsc2740 or rs00114 SWALL:Q8XVT7 (EMBL:AL646071) (140 aa) fasta scores: E(): 3.1e-32, 62.85% id in 140 aa, and to Neisseria meningitidis conserved hypothetical inner membrane protein nma2177 SWALL:Q9JSR1 (EMBL:AL162758) (145 aa) fasta scores: E(): 2.9e-22, 48.25% id in 143 aa. (140 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (441 aa)
hemBSimilar to Pseudomonas aeruginosa delta-aminolevulinic acid dehydratase HemB or Pa5243 SWALL:HEM2_PSEAE (SWALL:Q59643) (337 aa) fasta scores: E(): 2e-85, 70.3% id in 330 aa; Belongs to the ALAD family. (354 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (364 aa)
bfrBacterioferritin; Iron-storage protein. (158 aa)
BPSS1245Similar to Pseudomonas fluorescens uroporphyrin-III c-methyltransferase CobA SWALL:SUMT_PSEFL (SWALL:P37725) (247 aa) fasta scores: E(): 2.2e-32, 46.38% id in 235 aa, and to Xanthomonas campestris uroporphyrin-III c-methyltransferase CysG or xcc2010 SWALL:AAM41299 (EMBL:AE012305) (258 aa) fasta scores: E(): 1.5e-49, 63.55% id in 236 aa, and to Pseudomonas aeruginosa uroporphyrin-III c-methyltransferase CobA or pa1778 SWALL:Q9I2W4 (EMBL:AE004603) (245 aa) fasta scores: E(): 5e-37, 51.31% id in 228 aa; possible alternative start site at codon 41 and codon 44. (274 aa)
BPSS1278Putative membrane protein (fragment); Probable gene remnant. Similar to the C-terminal regions of Chromobacterium violaceum probable membrane transport protein SWALL:Q7NSV5 (EMBL:AE016921) (417 aa) fasta scores: E(): 1.6e-07, 33.77% id in 151 aa, and Mycobacterium paratuberculosis hypothetical protein SWALL:Q73SK8 (EMBL:AE017241) (453 aa) fasta scores: E(): 4.6e-09, 41.79% id in 134 aa. (432 aa)
BPSS2171Putative aminotransferase; Similar to Pseudomonas aeruginosa probable aminotransferase pa5523 SWALL:Q9HT50 (EMBL:AE004964) (450 aa) fasta scores: E(): 1.3e-107, 61.76% id in 442 aa. C-terminus is similar to the C-terminal region of Escherichia coli glutamate-1-semialdehyde 2,1-aminomutase HemL or Gsa or PopC SWALL:GSA_ECOLI (SWALL:P23893) (426 aa) fasta scores: E(): 3.3e-26, 31% id in 400 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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