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mrdA mrdA BPSL0195 BPSL0195 bpeA bpeA bpeB bpeB oprB oprB BPSL1802 BPSL1802 amrB amrB amrA amrA amrR amrR BPSL2015 BPSL2015 BPSL2104 BPSL2104 nagZ nagZ ftsI ftsI BPSL3094 BPSL3094 mrcA mrcA BPSS0238 BPSS0238 BPSS0562 BPSS0562 penA penA BPSS1120 BPSS1120 ftsI-3 ftsI-3 ftsI-2 ftsI-2 BPSS1287 BPSS1287 oxa oxa oppF oppF oppD oppD oppC oppC oppB oppB oppA oppA BPSS2304 BPSS2304
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
mrdAPenicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (818 aa)
BPSL0195Putative membrane protein; Similar to Neisseria meningitidis AmpG-related protein NMB0360 SWALL:Q9K133 (EMBL:AE002392) (427 aa) fasta scores: E(): 4.9e-90, 54.76% id in 420 aa, and to Neisseria gonorrhoeae glutamine synthetase SWALL:P95363 (EMBL:U82701) (427 aa) fasta scores: E(): 4.2e-88, 53.57% id in 420 aa. Possible alternative translational start site. (437 aa)
bpeASimilar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein A precursor acrA or MtcA or Lir SWALL:ACRA_ECOLI (SWALL:P31223) (397 aa) fasta scores: E(): 5.5e-60, 53.76% id in 385 aa, and to Ralstonia solanacearum probable acriflavin resistance lipoprotein A precursor rsc0011 or rs01833 SWALL:Q8Y3G9 (EMBL:AL646057) (398 aa) fasta scores: E(): 6.6e-61, 55.22% id in 402 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (420 aa)
bpeBSimilar to Escherichia coli acriflavine resistance protein B AcrB or AcrE or b0462 SWALL:ACRB_ECOLI (SWALL:P31224) (1049 aa) fasta scores: E(): 0, 66.63% id in 1049 aa, and to Klebsiella pneumoniae AcrB protein SWALL:Q93K40 (EMBL:AJ318073) (1048 aa) fasta scores: E(): 0, 66.79% id in 1048 aa. (1066 aa)
oprBSimilar to Pseudomonas aeruginosa outer membrane protein OprM precursor pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 4.1e-85, 55.67% id in 476 aa, and to Xanthomonas axonopodis outer membrane protein xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 5.8e-84, 53.72% id in 497 aa. (514 aa)
BPSL1802Multidrug efflux system putative membrane lipoprotein; Similar to Pseudomonas aeruginosa outer membrane protein precursor OprM or OprK or pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 2.3e-59, 46.39% id in 485 aa, and to Xanthomonas axonopodis outer membrane protein OprM or xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 9.5e-65, 47.54% id in 488 aa. (516 aa)
amrBMultidrug efflux system transporter protein AmrB; Almost identical to previously sequenced Burkholderia pseudomallei putative transporter AmrB SWALL:O87936 (EMBL:AF072887) (1043 aa) fasta scores: E(): 0, 99.8% id in 1043 aa. Similar to Escherichia coli acriflavine resistance protein B AcrB or AcrE or b0462 SWALL:ACRB_ECOLI (SWALL:P31224) (1049 aa) fasta scores: E(): 5.5e-199, 51.79% id in 1033 aa. (1043 aa)
amrAAlmost identical to Burkholderia pseudomallei putative membrane fusion protein AmrA SWALL:O87935 (EMBL:AF072887) (399 aa) fasta scores: E(): 7.7e-133, 99.74% id in 399 aa. Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein A precursor AcrA or MtcA or Lir or b0463 or z0578 or ecs0516 SWALL:ACRA_ECO57 (SWALL:P31223) (397 aa) fasta scores: E(): 3.5e-43, 40.1% id in 384 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (399 aa)
amrRTetR family regulatory protein; Almost identical to Burkholderia pseudomallei regulator AmrR SWALL:O87934 (EMBL:AF072887) (187 aa) fasta scores: E(): 1e-64, 99.42% id in 173 aa. Similar to Ralstonia solanacearum putative AcrAB operon repressor transcription regulator protein AcrR or rsc0012 or rs01834 SWALL:Q8Y3G8 (EMBL:AL646057) (219 aa) fasta scores: E(): 4.2e-21, 38.22% id in 225 aa. Note: This CDS is longer than the previously sequenced AmrR in its C-terminal region, it is possible that the previous sequence submitted to the databases had a sequencing error that led to a frameshift [...] (223 aa)
BPSL2015Putative membrane attached glycosyl hydrolase; Similar to Alteromonas sp. beta-hexosaminidase A precursor Cht60 SWALL:HEXA_ALTSO (SWALL:P48823) (598 aa) fasta scores: E(): 2.1e-59, 35.98% id in 628 aa, and to Ralstonia solanacearum putative hydrolase glycosidase protein rsc0769 or rs05085 SWALL:Q8Y1C1 (EMBL:AL646060) (734 aa) fasta scores: E(): 3.1e-152, 61.84% id in 684 aa; Belongs to the glycosyl hydrolase 3 family. (682 aa)
BPSL2104Putative penicillin-binding protein; Similar to Ralstonia solanacearum probable penicillin-binding 1 rsc2976 or rs01357 SWALL:Q8XV55 (EMBL:AL646073) (801 aa) fasta scores: E(): 2.2e-183, 61.61% id in 805 aa, and to Neisseria lactamica penicillin-binding protein 1A MrcA or PonA SWALL:PBPA_NEILA (SWALL:O87579) (798 aa) fasta scores: E(): 4.3e-129, 47.4% id in 791 aa. Note: This CDS is longer in its N-terminal region than most of its database matches. (852 aa)
nagZPutative beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (342 aa)
ftsIPeptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (614 aa)
BPSL3094Putative outer membrane bacteriocin efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. (482 aa)
mrcASimilar to Escherichia coli penicillin-binding protein 1A MrcA or PonA or b3396 SWALL:PBPA_ECOLI (SWALL:P02918) (850 aa) fasta scores: E(): 1.9e-88, 38.63% id in 818 aa. (773 aa)
BPSS0238Similar to Bacillus subtilis penicillin-binding protein 1A/1B PonA SWALL:PBPA_BACSU (SWALL:P39793) (914 aa) fasta scores: E(): 8.7e-44, 30.94% id in 685 aa, and to Escherichia coli penicillin-binding protein 1B MrcB or PonB or PbpF or b0149 SWALL:PBPB_ECOLI (SWALL:P02919) (844 aa) fasta scores: E(): 9.3e-43, 31.98% id in 591 aa. (720 aa)
BPSS0562Putative porin protein; Similar to Burkholderia cepacia major porin protein OpcP1 SWALL:Q45106 (EMBL:D63823) (361 aa) fasta scores: E(): 1e-29, 38.07% id in 394 aa, and to Alcaligenes eutrophus hypothetical protein SWALL:Q44021 (EMBL:L36817) (390 aa) fasta scores: E(): 1.1e-32, 39.34% id in 399 aa. (380 aa)
penABeta-lactamase precursor; Similar to Yersinia enterocolitica beta-lactamase precursor BlaA SWALL:BLAC_YEREN (SWALL:Q01166) (294 aa) fasta scores: E(): 1.5e-60, 57.43% id in 289 aa. Previously sequenced as Burkholderia pseudomallei class A beta-lactamase PenA or Bla-BPS-1d SWALL:Q932Y0 (EMBL:AY032872) (295 aa) fasta scores: E(): 4.9e-114, 100% id in 295 aa. (295 aa)
BPSS1120Putative outer membrane efflux protein; Similar to Pseudomonas putida efflux protein TtgC SWALL:Q9WWZ8 (EMBL:AF031417) (484 aa) fasta scores: E(): 9.1e-76, 49.68% id in 483 aa, and to Pseudomonas aeruginosa outer membrane protein OprM precursor or OprK or pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 3.8e-85, 56.19% id in 468 aa, and to Xanthomonas axonopodis outer membrane protein OprM or xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 5.4e-84, 53.18% id in 502 aa. (512 aa)
ftsI-3Putative penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (594 aa)
ftsI-2Similar to Neisseria gonorrhoeae penicillin-binding protein 2 PenA SWALL:PBP2_NEIGO (SWALL:P08149) (581 aa) fasta scores: E(): 1.9e-65, 37.97% id in 574 aa, and to Ralstonia solanacearum probable penicillin-binding 3 precursor pbp-3 transmembrane protein FtsI or rsc2850 or rs00255 SWALL:Q8XVI1 (EMBL:AL646072) (595 aa) fasta scores: E(): 1e-84, 46.4% id in 556 aa, and to Xanthomonas axonopodis penicillin-binding protein 3 FtsI or xac0774 SWALL:AAM35662 (EMBL:AE011708) (622 aa) fasta scores: E(): 2.7e-68, 40.76% id in 547 aa. (570 aa)
BPSS1287Putative outer membrane efflux protein; Similar to Enterobacter aerogenes TolC protein precursor SWALL:Q8VLQ0 (EMBL:AJ421426) (486 aa) fasta scores: E(): 1e-19, 26.16% id in 451 aa, and to Ralstonia solanacearum probable porin rsc0695 or rs01600 SWALL:Q8Y1J5 (EMBL:AL646060) (484 aa) fasta scores: E(): 4.3e-25, 27.8% id in 446 aa. (446 aa)
oxaBeta-lactamase precursor; Almost identical to the previously sequenced Burkholderia pseudomallei beta-lactamase precursor Oxa SWALL:CAD32565 (EMBL:AJ488303) (269 aa) fasta scores: E(): 2.2e-111, 99.62% id in 269 aa. Similar to Pseudomonas aeruginosa beta-lactamase Oxa-18 precursor SWALL:BLOI_PSEAE (SWALL:O07293) (275 aa) fasta scores: E(): 2.4e-37, 43.07% id in 267 aa. (269 aa)
oppFSimilar to Salmonella typhimurium oligopeptide transport ATP-binding protein OppF or stm1742 SWALL:OPPF_SALTY (SWALL:P08007) (334 aa) fasta scores: E(): 1e-57, 58.07% id in 322 aa, and to Yersinia pestis oligopeptide transport ATP-binding protein OppF or ypo2186 or y2030 SWALL:Q8ZEI4 (EMBL:AJ414151) (333 aa) fasta scores: E(): 1.1e-58, 59.31% id in 322 aa. CDS is extended at the N-terminus in comparison to orthologues; Belongs to the ABC transporter superfamily. (377 aa)
oppDSimilar to Salmonella typhimurium oligopeptide transport ATP-binding protein OppD or stm1743 SWALL:OPPD_SALTY (SWALL:P04285) (335 aa) fasta scores: E(): 1.3e-59, 57.45% id in 322 aa, and to Yersinia pestis oligopeptide transport ATP-binding protein OppD or ypo2185 or y2029 SWALL:Q8ZEI5 (EMBL:AJ414151) (333 aa) fasta scores: E(): 2.8e-61, 59% id in 322 aa, and to Salmonella typhi oligopeptide transport ATP-binding protein OppD sty1308 SWALL:Q8Z7E8 (EMBL:AL627269) (335 aa) fasta scores: E(): 8.8e-60, 57.76% id in 322 aa; Belongs to the ABC transporter superfamily. (329 aa)
oppCSimilar to Salmonella typhimurium oligopeptide transport system permease protein OppC or stm1744 SWALL:OPPC_SALTY (SWALL:P08006) (302 aa) fasta scores: E(): 1e-56, 54.74% id in 274 aa, and to Vibrio cholerae oligopeptide ABC transporter, permease protein vc1093 SWALL:Q9KT12 (EMBL:AE004190) (300 aa) fasta scores: E(): 2.2e-57, 54.24% id in 271 aa, and to Haemophilus influenzae oligopeptide transport system permease protein OppC or hi1122 SWALL:OPPC_HAEIN (SWALL:P45053) (311 aa) fasta scores: E(): 7e-57, 54.01% id in 274 aa. (300 aa)
oppBSimilar to Salmonella typhimurium oligopeptide transport system permease protein OppB or stm1745 SWALL:OPPB_SALTY (SWALL:P08005) (306 aa) fasta scores: E(): 1e-59, 48.71% id in 312 aa, and to Yersinia pestis oligopeptide transport system permease protein OppB or ypo2183 or y2027 SWALL:Q8ZEI7 (EMBL:AJ414151) (306 aa) fasta scores: E(): 2.1e-61, 51.6% id in 312 aa, and to Haemophilus influenzae oligopeptide transport system permease protein OppB or hi1123 SWALL:OPPB_HAEIN (SWALL:P45054) (306 aa) fasta scores: E(): 8.8e-61, 51.92% id in 312 aa. (312 aa)
oppASimilar to Salmonella typhimurium periplasmic oligopeptide-binding protein precursor OppA or stm1746 SWALL:OPPA_SALTY (SWALL:P06202) (543 aa) fasta scores: E(): 1e-86, 42.93% id in 545 aa, and to Escherichia coli O157:H7 oligopeptide transport, periplasmic binding protein OppA or z2019 or ecs1743 SWALL:Q8XDA4 (EMBL:AE005341) (543 aa) fasta scores: E(): 6.6e-87, 42.75% id in 545 aa. (554 aa)
BPSS2304Penicillin-binding protein; Internal region is similar to an internal region of Escherichia coli penicillin-binding protein 1A MrcA or PonA SWALL:PBPA_ECOLI (SWALL:P02918) (850 aa) fasta scores: E(): 1.4e-21, 30.8% id in 737 aa. C-terminal region is similar to Chlorobium tepidum penicillin-binding protein 1 CT0176 SWALL:AAM71424 (EMBL:AE012797) (763 aa) fasta scores: E(): 1.5e-58, 36.31% id in 771 aa. (839 aa)
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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