| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score | 
| CA_C1731 | adk | CA_C1731 | CA_C3112 | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.  | 0.906 | 
| CA_C1731 | dxs | CA_C1731 | CA_C2077 | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.  | 0.712 | 
| CA_C1731 | rsgA | CA_C1731 | CA_C1729 | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | Predicted GTPase (YLOQ B.subtilis ortholog); One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.  | 0.989 | 
| CA_C1731 | tenI | CA_C1731 | CA_C2920 | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | Thiamine monophosphate synthase.  | 0.774 | 
| CA_C1731 | thiC | CA_C1731 | CA_C0495 | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | Thiamine monophosphate syntase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.  | 0.794 | 
| CA_C1731 | thiC-2 | CA_C1731 | CA_C3014 | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.  | 0.782 | 
| CA_C1731 | thiG | CA_C1731 | CA_C2922 | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | Uncharacterized enzyme of thiazol biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.  | 0.779 | 
| CA_C1731 | thiH | CA_C1731 | CA_C1356 | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | Thiamine biosynthesis enzyme ThiH.  | 0.752 | 
| CA_C1731 | thiH-2 | CA_C1731 | CA_C2921 | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | Thiamine biosynthesis enzyme, thiH.  | 0.753 | 
| CA_C1731 | thiI | CA_C1731 | CA_C2971 | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | Thiamine biosynthesis enzyme, THII; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.  | 0.758 | 
| CA_C1731 | thiK-2 | CA_C1731 | CA_C3096 | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | Hydroxyethylthiazole kinase ThiM/ThiK (FS); Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.  | 0.793 | 
| CA_C2923 | tenI | CA_C2923 | CA_C2920 | Dinucleotide-utilizing enzyme involved in molybdopterin/thiamine biosynthesis.  | Thiamine monophosphate synthase.  | 0.833 | 
| CA_C2923 | thiC | CA_C2923 | CA_C0495 | Dinucleotide-utilizing enzyme involved in molybdopterin/thiamine biosynthesis.  | Thiamine monophosphate syntase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.  | 0.627 | 
| CA_C2923 | thiG | CA_C2923 | CA_C2922 | Dinucleotide-utilizing enzyme involved in molybdopterin/thiamine biosynthesis.  | Uncharacterized enzyme of thiazol biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.  | 0.989 | 
| CA_C2923 | thiH-2 | CA_C2923 | CA_C2921 | Dinucleotide-utilizing enzyme involved in molybdopterin/thiamine biosynthesis.  | Thiamine biosynthesis enzyme, thiH.  | 0.932 | 
| CA_C2923 | thiI | CA_C2923 | CA_C2971 | Dinucleotide-utilizing enzyme involved in molybdopterin/thiamine biosynthesis.  | Thiamine biosynthesis enzyme, THII; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.  | 0.900 | 
| adk | CA_C1731 | CA_C3112 | CA_C1731 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.  | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | 0.906 | 
| adk | rsgA | CA_C3112 | CA_C1729 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.  | Predicted GTPase (YLOQ B.subtilis ortholog); One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.  | 0.900 | 
| dxs | CA_C1731 | CA_C2077 | CA_C1731 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.  | Predicted nucleotide-binding protein, YLOS B.subtilis ortholog.  | 0.712 | 
| dxs | tenI | CA_C2077 | CA_C2920 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.  | Thiamine monophosphate synthase.  | 0.731 |