STRINGSTRING
tcdE tcdE tcdR tcdR tcdB tcdB tcdA tcdA tcdC tcdC rgbR rgbR agrD agrD agrB agrB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tcdEHolin-like pore-forming protein. (166 aa)
tcdRAlternative RNA polymerase sigma factors. (184 aa)
tcdBToxin B. (2366 aa)
tcdAExperimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651. (2710 aa)
tcdCNegative regulator of toxin gene expression. (232 aa)
rgbRTwo-component response regulator VirR-like. (237 aa)
agrDAutoinducer prepeptide. (48 aa)
agrBAccessory gene regulator. (192 aa)
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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