STRINGSTRING
pycA pycA acoC acoC acoL acoL CAJ66859.1 CAJ66859.1 VorC1 VorC1 VorB1 VorB1 VorA1 VorA1 VorA'1 VorA'1 CAJ66960.1 CAJ66960.1 CAJ66993.1 CAJ66993.1 cooS cooS CAJ66997.1 CAJ66997.1 gluD gluD CAJ67027.1 CAJ67027.1 CAJ67062.1 CAJ67062.1 CAJ67108.1 CAJ67108.1 CAJ67109.1 CAJ67109.1 CAJ67110.1 CAJ67110.1 CAJ67111.1 CAJ67111.1 CAJ67113.1 CAJ67113.1 adhE adhE ldhA ldhA fba fba CAJ67321.1 CAJ67321.1 CAJ67322.1 CAJ67322.1 gapN gapN cooS1 cooS1 fhs fhs folD folD metF metF LpdA LpdA AcsD AcsD AcsC AcsC AcsE AcsE CdhC CdhC CAJ67574.1 CAJ67574.1 plfB plfB CAJ67662.1 CAJ67662.1 acnB acnB icd icd serA serA fumA fumA fumB fumB bcd2 bcd2 hbd hbd thlA1 thlA1 mgsA mgsA hom1 hom1 CAJ68026.1 CAJ68026.1 ackA ackA fbp fbp dapG dapG glnA glnA sseA sseA aspB1 aspB1 pgm pgm hom2 hom2 cysK cysK cysE cysE cysM cysM YjjG YjjG gapB gapB CAJ68678.1 CAJ68678.1 CAJ68684.1 CAJ68684.1 eutE eutE pduL pduL accA accA accD accD accC accC accB accB CAJ68847.2 CAJ68847.2 CAJ68912.1 CAJ68912.1 argM argM lysA lysA lysC lysC thrC thrC thrB thrB gabT gabT ldh ldh CAJ69080.1 CAJ69080.1 VorA'2 VorA'2 VorA2 VorA2 VorB2 VorB2 VorC2 VorC2 aldH aldH asrC asrC asrB asrB asrA asrA fruABC fruABC araD araD rpe rpe rpiB1 rpiB1 tkt tkt tkt1 tkt1 tal tal abfD abfD cat1 cat1 ppdK ppdK VorA'3 VorA'3 VorA3 VorA3 VorB3 VorB3 VorC3 VorC3 CAJ69317.1 CAJ69317.1 GlcK GlcK CAJ69375.1 CAJ69375.1 CAJ69440.1 CAJ69440.1 CAJ69443.1 CAJ69443.1 CAJ69455.1 CAJ69455.1 CAJ69456.1 CAJ69456.1 CAJ69457.1 CAJ69457.1 rpe1 rpe1 dapF dapF ltaE ltaE thlA2 thlA2 scoA scoA scoB scoB pfo pfo CAJ69569.1 CAJ69569.1 glyA glyA pgmA pgmA glyA1 glyA1 Nit Nit phnXW phnXW CAJ69743.1 CAJ69743.1 adhE1 adhE1 CAJ69864.1 CAJ69864.1 AdhB AdhB CAJ69907.1 CAJ69907.1 CAJ69908.1 CAJ69908.1 CAJ69909.1 CAJ69909.1 tagABC tagABC tagK tagK garK garK pfp pfp CAJ70025.1 CAJ70025.1 CAJ70027.1 CAJ70027.1 GatY2 GatY2 eno eno gpmI gpmI tpi tpi pgk pgk gapA gapA dapA2 dapA2 asd asd dapA3 dapA3 dapB1 dapB1 dapH dapH dapB2 dapB2 pgi pgi pyk pyk pfkA pfkA sirC sirC hemB hemB cobA cobA hemC hemC tkt2 tkt2 tkt3 tkt3 rpiB2 rpiB2 prs prs CAJ70533.1 CAJ70533.1 dapA4 dapA4 CAJ70536.1 CAJ70536.1 CAJ70537.1 CAJ70537.1 CAJ70548.1 CAJ70548.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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pycAPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1143 aa)
acoCAcetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (348 aa)
acoLAcetoin dehydrogenase E3 component (dihydrolipoamide dehydrogenase). (576 aa)
CAJ66859.1Putative sugar-phosphate aldolase. (216 aa)
VorC1Putative 4Fe-4S ferredoxin, iron-sulfur binding domain protein, delta subunit; Experimentally verified as part of mature spore proteome PMID:19542279. (71 aa)
VorB1Putative ferredoxin/flavodoxin oxidoreductase,alpha subunit. (359 aa)
VorA1Putative ferredoxin/flavodoxin oxidoreductase,beta subunit. (250 aa)
VorA'1Putative ferredoxin/flavodoxin oxidoreductase,gamma subunit; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651. (185 aa)
CAJ66960.1Putative peptidase. (350 aa)
CAJ66993.1Fwde family protein. (179 aa)
cooSCarbon monoxide dehydrogenase; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651. (633 aa)
CAJ66997.1Putative oxidoreductase, Fe-S subunit. (157 aa)
gluDNAD-specific glutamate dehydrogenase; Previously characterized in Clostridium difficile as NAD-specific glutamate dehydrogenase GluD (SWALL:P27346).Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (421 aa)
CAJ67027.1PTS system, fructose-like IIA component; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651. (150 aa)
CAJ67062.1Flagella glycosylation phosphoserine phosphatase; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651. (200 aa)
CAJ67108.1PTS system, mannose/fructose/sorbose IIA component. (133 aa)
CAJ67109.1PTS system, mannose/fructose/sorbose IIB component. (162 aa)
CAJ67110.1PTS system, mannose/fructose/sorbose IIC component; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651. (251 aa)
CAJ67111.1PTS system, mannose/fructose/sorbose IID component. (287 aa)
CAJ67113.1Putative peptidase, M20A family. (435 aa)
adhEAldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (880 aa)
ldhAD-lactate dehydrogenase; Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
fbaFructose-1,6-bisphosphate aldolase; Experimentally verified as part of mature spore proteome PMID:19542279. (308 aa)
CAJ67321.1PTS system, mannose/fructose/sorbose IIB component. (157 aa)
CAJ67322.1PTS system, mannose/fructose/sorbose IIC component. (252 aa)
gapNGlyceraldehyde-3-phosphate dehydrogenase (NADP(+)) (GADPH); Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the aldehyde dehydrogenase family. (486 aa)
cooS1Bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase (CODH); Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651. (639 aa)
fhsFormate--tetrahydrofolate ligase (Formyltetrahydrofolate synthetase) (FHS) (FTHFS). (558 aa)
folDBifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
metF5,10-methylenetetrahydrofolate reductase; Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651; Belongs to the methylenetetrahydrofolate reductase family. (293 aa)
LpdABifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase, dihydrolipoyl dehydrogenase subunit. (461 aa)
AcsDBifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase, subunit delta. (314 aa)
AcsCBifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase, delta subunit. (455 aa)
AcsEBifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase, methyltransferase subunit; Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651. (268 aa)
CdhCBifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase, subunit alpha/beta. (708 aa)
CAJ67574.1Putative pyridoxal phosphate-dependent aminotransferase. (365 aa)
plfBFormate acetyltransferase (Pyruvate formate-lyase); Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279. (743 aa)
CAJ67662.1Putative oxidative stress glutamate synthase; Belongs to the glutamate synthase family. (480 aa)
acnBAconitate hydratase (Citrate hydro-lyase). (641 aa)
icdIsocitrate dehydrogenase NAD-dependent; Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651. (331 aa)
serAPutative D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa)
fumAFumarate hydratase class I, subunit A. (279 aa)
fumBFumarate hydratase class I, subunit B. (182 aa)
bcd2Butyryl-CoA dehydrogenase; Function experimentally characterised PMID:23772070. Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279. (378 aa)
hbd3-hydroxybutyryl-CoA dehydrogenase; Function experimentally characterised PMID:23772070. Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651 .Experimentally verified as part of mature spore proteome PMID:19542279. (281 aa)
thlA1Acetoacetyl-CoA thiolase 1; Function experimentally characterised PMID:23772070. Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
mgsAMethylglyoxal synthase (MGS); Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (137 aa)
hom1Homoserine dehydrogenase. (401 aa)
CAJ68026.1Putative FAD-linked oxidase. (463 aa)
ackAAcetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
fbpFructose-1,6-bisphosphatase; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant. Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651. (661 aa)
dapGAspartokinase 1 (Aspartokinase I) (1spartate kinase I); Belongs to the aspartokinase family. (407 aa)
glnAGlutamine synthetase. (632 aa)
sseA3-mercaptopyruvate sulfurtransferase. (283 aa)
aspB1Putative glutamate synthase. (464 aa)
pgmAlpha-phosphoglucomutase. (565 aa)
hom2Homoserine dehydrogenase. (405 aa)
cysKO-acetyl-serine thiol-lyase A (O-acetyl-sulfhydrylase)(OAS-TL); Experimentally verified as part of mature spore proteome PMID:19542279. (302 aa)
cysESerine acetyltransferase (SAT); Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: down-regulated in Spo0A mutant PMID:24568651. (196 aa)
cysMO-acetylserine (thiol)-lyase (O-acetylserine sulfhydrylase) (OAS-TL). (320 aa)
YjjGPutative hydrolase. (228 aa)
gapBGlyceraldehyde-3-phosphate dehydrogenase (GAPDH); Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)
CAJ68678.1Pyridoxal-dependent decarboxylase, group IV decarboxylase family. (403 aa)
CAJ68684.1Putative phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (213 aa)
eutEEthanolamine acetaldehyde oxydoreductase. (489 aa)
pduLPutative ethanolamine utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (209 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (314 aa)
accDAcetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (284 aa)
accCAcetyl-CoA carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (453 aa)
accBAcetyl-CoA carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (150 aa)
CAJ68847.2Putative peptidase, M20A family; Experimentally verified as part of mature spore proteome PMID:19542279. (448 aa)
CAJ68912.1N-carbamoyl-L-amino acid hydrolase. (405 aa)
argMSuccinylornithine transaminase (ACOAT); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (395 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (430 aa)
lysCAspartokinase; Belongs to the aspartokinase family. (397 aa)
thrCThreonine synthase. (493 aa)
thrBHomoserine kinase (HSK) (HK); Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (297 aa)
gabT4-aminobutyrate aminotransferase; Experimentally verified through Mass Spectrometry as part of Spo0A regulated proteome: up-regulated in Spo0A mutant PMID:24568651. Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa)
ldhL-lactate dehydrogenase (L-LDH); Catalyzes the conversion of lactate to pyruvate. (322 aa)
CAJ69080.1Putative succinyl-CoA synthetase-like ATP-binding protein. (699 aa)
VorA'2Putative ferredoxin/flavodoxin oxidoreductase,gamma subunit. (179 aa)
VorA2Putative ferredoxin/flavodoxin oxidoreductase,beta subunit. (246 aa)
VorB2Putative ferredoxin/flavodoxin oxidoreductase,alpha subunit. (349 aa)
VorC2Putative 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (78 aa)
aldHAldehyde dehydrogenase (aldehyde:NAD+ oxidoreductase); Belongs to the aldehyde dehydrogenase family. (454 aa)
asrCAnaerobic sulfite reductase subunit C; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (323 aa)
asrBAnaerobic sulfite reductase subunit B. (263 aa)
asrAAnaerobic sulfite reductase subunit A (Anaerobic sulfite reductase iron-sulfur subunit). (335 aa)
fruABCFragment of membrane protein, abortive infection-type protein. (639 aa)
araDL-ribulose-5-phosphate 4-epimerase (Phosphoribulose isomerase). (228 aa)
rpePutative ribulose-phosphate 3-epimerase. (221 aa)
rpiB1Ribose-5-phosphate isomerase B1 (Phosphoriboisomerase B). (148 aa)
tktTransketolase, C-terminal section; Experimentally verified as part of mature spore proteome PMID:19542279. (306 aa)
tkt1Transketolase, N-terminal section; Experimentally verified as part of mature spore proteome PMID:19542279. (270 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (216 aa)
abfDGamma-aminobutyrate metabolism dehydratase/isomerase [includes: 4-hydroxybutyryl-coa dehydratase; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651. (498 aa)
cat1Succinyl-CoA:coenzyme A transferase; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651. (514 aa)
ppdKPyruvate phosphate dikinase (ATP:pyruvate,phosphate phosphotransferase); Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the PEP-utilizing enzyme family. (875 aa)
VorA'3Putative flavodoxin/ferredoxin oxidoreductase gamma subunit. (179 aa)
VorA3Putative flavodoxin/ferredoxin oxidoreductase beta subunit. (239 aa)
VorB3Putative flavodoxin/ferredoxin oxidoreductase alpha subunit. (358 aa)
VorC3Putative 4Fe-4S ferredoxin, iron-sulfur binding domain protein, delta subunit. (65 aa)
CAJ69317.1Putative nitrite/sulphite reductase; Experimentally verified as part of mature spore proteome PMID:19542279. (515 aa)
GlcKPutative glucokinase, ROK family. (311 aa)
CAJ69375.1PTS system, fructose-like IIA component. (151 aa)
CAJ69440.1PTS system, fructose/mannitol family IIC component. (419 aa)
CAJ69443.1PTS system, fructose/mannitol-family IIB component. (95 aa)
CAJ69455.1PTS system, mannose-specfic IIA component. (150 aa)
CAJ69456.1PTS system, mannose-specfic IIB component. (102 aa)
CAJ69457.1PTS system, mannose-specfic IIC component. (368 aa)
rpe1Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) (PPE) (R5P3E); Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa)
dapFDiaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (276 aa)
ltaELow specificity L-threonine aldolase. (344 aa)
thlA2Acetoacetyl-CoA thiolase 2; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
scoASuccinyl CoA:3-oxoacid CoA-transferase subunit A. (218 aa)
scoBSuccinyl CoA:3-oxoacid CoA-transferase subunit B. (221 aa)
pfoPyruvate-ferredoxin oxidoreductase; Experimentally verified as part of mature spore proteome PMID:19542279. (1179 aa)
CAJ69569.1Putative propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (189 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (414 aa)
pgmAAlpha-phosphoglucomutase. (568 aa)
glyA1Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
NitNitrilase (carbon-nitrogen hydrolase). (308 aa)
phnXWBifunctional phosphonoacetaldehyde hydrolase/aminoethylphosphonate transaminase; Involved in phosphonate degradation; In the N-terminal section; belongs to the HAD-like hydrolase superfamily. PhnX family. (636 aa)
CAJ69743.1Putative NAD(P)-binding oxidoreductase. (339 aa)
adhE1Aldehyde-alcohol dehydrogenase; Experimentally verified as part of mature spore proteome PMID:19542279; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (867 aa)
CAJ69864.1Putative thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (378 aa)
AdhBAlcohol dehydrogenase. (381 aa)
CAJ69907.1PTS system, mannose-specfic IIC component. (371 aa)
CAJ69908.1PTS system, mannose-specfic IIB component. (106 aa)
CAJ69909.1PTS system, mannose-specfic IIA component. (153 aa)
tagABCPTS system, tagatose-specific IIABC component. (638 aa)
tagKTagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (306 aa)
garKGlycerate kinase; Belongs to the glycerate kinase type-1 family. (384 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (404 aa)
CAJ70025.1PTS system, fructose-like IIA component. (149 aa)
CAJ70027.1PTS system, fructose-like IIABC component. (631 aa)
GatY2Putative fructose-1-6-bisphosphate aldolase. (292 aa)
enoEnolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (510 aa)
tpiTriosephosphate isomerase (TIM) (Triose-phosphate isomerase); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (247 aa)
pgkPhosphoglycerate kinase; Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the phosphoglycerate kinase family. (400 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase (GAPDH); Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
dapA2Dihydrodipicolinate synthase 2; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (333 aa)
dapA3Dihydrodipicolinate synthase 3; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
dapB1Dihydrodipicolinate reductase 1 (DHPR 1); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (249 aa)
dapH2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (238 aa)
dapB2Dihydrodipicolinate reductase 2 (DHPR 2); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (251 aa)
pgiGlucose-6-phosphate isomerase; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: down-regulated in Spo0A mutant PMID:24568651. Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the GPI family. (449 aa)
pykPyruvate kinase (PK); Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the pyruvate kinase family. (586 aa)
pfkA6-phosphofructokinase (Phosphofructokinase) (Phosphohexokinase); Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
sirCPrecorrin-2 dehydrogenase. (192 aa)
hemBDelta-aminolevulinic acid dehydratase (porphobilinogen synthase); Belongs to the ALAD family. (321 aa)
cobABifunctional uroporphyrinogen-III methyltransferase/uroporphyrinogen-III synthase. (499 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (301 aa)
tkt2Transketolase, pyridine binding subunit. (313 aa)
tkt3Transketolase, thiamine diphosphate binding subunit. (275 aa)
rpiB2Ribose-5-phosphate isomerase 2. (150 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa)
CAJ70533.1Putative 4-hydroxy-2-oxoglutarate aldolase. (210 aa)
dapA4Dihydrodipicolinate synthase 4 (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa)
CAJ70536.1PTS system, fructose/mannitol-family IIC component. (423 aa)
CAJ70537.1PTS system, fructose/mannitol-family IIB component. (95 aa)
CAJ70548.1Putative ribokinase family sugar kinase. (330 aa)
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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