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| | GDI3750 | Putative Propionate--CoA ligase. (586 aa) |
| | nadK | Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (267 aa) |
| | GDI0036 | Putative phosphoglycerate mutase. (179 aa) |
| | plsY | Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (212 aa) |
| | pyrC | Putative dihydro-orotase protein. (430 aa) |
| | pyrB | Putative spartate carbamoyltransferase, catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (321 aa) |
| | GDI0067 | Putative histidine triad (HIT) protein. (128 aa) |
| | GDI0088 | Conserved hypothetical protein. (348 aa) |
| | GDI0124 | Putative Ubiquitin-activating enzyme. (574 aa) |
| | GDI0150 | Conserved hypothetical protein. (400 aa) |
| | mobB | Putatie molybdopterin-guanine dinucleotide biosynthesis protein B. (177 aa) |
| | mobA | Putative molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (210 aa) |
| | GDI0182 | Conserved hypothetical protein; Belongs to the UPF0434 family. (63 aa) |
| | accC | Putative Biotin carboxylase (Acetyl-CoA carboxylase subunit A); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (452 aa) |
| | pdxA | Putative 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (334 aa) |
| | GDI0241 | Putative transketolase. (688 aa) |
| | GDI0257 | Putative sensor histidine kinase. (396 aa) |
| | glpD | Putative glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (540 aa) |
| | dhaK | Putative PTS-dependent dihydroxyacetone kinase. (333 aa) |
| | ptsP | Phosphoenolpyruvate-protein phosphotransferase ptsP; Belongs to the PEP-utilizing enzyme family. (765 aa) |
| | glpK | Putative glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (499 aa) |
| | GDI0283 | Conserved protein. (174 aa) |
| | tktA | Putative outer membrane protein (pseudogene); Belongs to the transketolase family. (775 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. (955 aa) |
| | gnd | 6-phosphogluconate dehydrogenase. (332 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (510 aa) |
| | GDI3812 | Putative signalling protein, GGDEF family. (855 aa) |
| | GDI0289 | Phosphatase. (292 aa) |
| | GDI0290 | Phosphatase. (273 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (245 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (234 aa) |
| | GDI0293 | Putative shikimate kinase. (182 aa) |
| | GDI0323 | Putative glyoxalase. (172 aa) |
| | iolC | Putative myo-inositol catabolism, sugar kinase protein. (642 aa) |
| | GDI0428 | Conserved hypothetical protein. (196 aa) |
| | modD | Putative pyrophosphorylase modD; Belongs to the NadC/ModD family. (273 aa) |
| | GDI0459 | Putative haloalkanoic acid dehalogenase. (222 aa) |
| | fbaB | Fructose-bisphosphate aldolase class 1. (309 aa) |
| | suhB | Inositol-1-monophosphatase. (270 aa) |
| | thiE | Putative thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (212 aa) |
| | GDI0518 | Putative acyl-CoA thioester hydrolase. (142 aa) |
| | amn | Putative AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (491 aa) |
| | GDI0565 | Putative glyoxalase. (262 aa) |
| | nadA | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (328 aa) |
| | nadB | Putative L-aspartate oxidase. (518 aa) |
| | nadC | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (284 aa) |
| | GDI0573 | Putative low molecular weight phosphotyrosine protein phosphatase. (157 aa) |
| | ribF | Putative riboflavin biosynthesis protein; Belongs to the ribF family. (315 aa) |
| | thiC | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (626 aa) |
| | glxK | Glycerate kinase; Belongs to the glycerate kinase type-1 family. (379 aa) |
| | GDI0628 | Inositol-3-phosphate synthase. (375 aa) |
| | pssA | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (314 aa) |
| | GDI0663 | Putative phosphoglycerate mutase protein. (208 aa) |
| | GDI0669 | Putative UDP-2,3-diacylglucosamine hydrolase. (275 aa) |
| | GDI0674 | Putative two-component sensor histidine kinase. (479 aa) |
| | atpH | ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (198 aa) |
| | atpA | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa) |
| | atpG | Putative ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (293 aa) |
| | atpD | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (493 aa) |
| | atpC | ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. (141 aa) |
| | GDI0702 | Inosine-guanosine kinase. (338 aa) |
| | ispE | Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (305 aa) |
| | GDI0732 | Putative two component sensor histidine kinase. (464 aa) |
| | GDI0760 | Conserved hypothetical protein. (283 aa) |
| | moaB | Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (189 aa) |
| | folE | GTP cyclohydrolase I. (205 aa) |
| | add | Putative adenosine deaminase. (479 aa) |
| | thiED | Putative bifunctional thiED protein. (269 aa) |
| | GDI0833 | Putative signalling protein, GGDEF family. (730 aa) |
| | cobP | Putative bifunctional adenosylcobalamin biosynthesis protein cobP; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (200 aa) |
| | pyrD | Putative dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (357 aa) |
| | thyX | Putative thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (316 aa) |
| | GDI0869 | Conserved hypothetical protein. (181 aa) |
| | GDI0873 | Putative signalling protein, GGDEF family. (350 aa) |
| | nadE | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (742 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa) |
| | gpmB | Probable phosphoglycerate mutase gpmB. (199 aa) |
| | nadD | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (215 aa) |
| | pdxA-2 | Putative 4-hydroxythreonine-4-phosphate dehydrogenase 2. (305 aa) |
| | GDI0962 | Putative serine/threonine protein kinase. (513 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (230 aa) |
| | hldE | D-beta-D-heptose 1-phosphate adenylyltransferase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (484 aa) |
| | fdhH | Formate dehydrogenase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (758 aa) |
| | fdhD | Putative formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (285 aa) |
| | GDI1165 | Putative diacylglycerol kinase family protein. (291 aa) |
| | GDI1168 | Conserved protein. (673 aa) |
| | purU | Putative formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (309 aa) |
| | atpF | Putative ATP synthase; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (164 aa) |
| | atpF-2 | Putative ATP synthase; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (203 aa) |
| | atpE | Putative ATP synthase; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (74 aa) |
| | atpB | Putative ATP synthase; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (249 aa) |
| | purH | Bifunctional purine biosynthesis protein purH. (525 aa) |
| | ptsI | Putative phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (618 aa) |
| | manX | Putative phosphotransferase enzyme IIA. (165 aa) |
| | GDI1190 | Putative HPr kinase. (161 aa) |
| | GDI1194 | Putative two-component system sensor protein. (368 aa) |
| | Maf-like | Putative septum formation inhibitor protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (251 aa) |
| | GDI1236 | Putative histidine kinase. (369 aa) |
| | GDI1240 | Putative Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase); Belongs to the thiolase-like superfamily. Thiolase family. (412 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (309 aa) |
| | chvG | Putative histidine kinase sensory protein. (592 aa) |
| | pykA | Pyruvate kinase; Belongs to the pyruvate kinase family. (479 aa) |
| | moeB | Molybdopterin biosynthesis protein moeB. (268 aa) |
| | folD | Putative FolD bifunctional protein [Includes: Methylenetetrahydrofolat dehydrogenase (EC 1.5.1.5); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (311 aa) |
| | GDI1308 | Putative NUDIX/MutT-family protein. (192 aa) |
| | podA | Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (896 aa) |
| | GDI1319 | Conserved hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (282 aa) |
| | pyrF | Putative Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (235 aa) |
| | pdxA-3 | Putative 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (330 aa) |
| | apt | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (176 aa) |
| | accC-2 | Biotin carboxylase protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | GDI1373 | Conserved protein. (350 aa) |
| | GDI1377 | Putative HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (205 aa) |
| | GDI1389 | Putative histidine kinase. (463 aa) |
| | GDI1402 | Conserved hypothetical protein. (239 aa) |
| | zwf-2 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (514 aa) |
| | sucA | 2-oxoglutarate dehydrogenase E1 component. (956 aa) |
| | sucB | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (476 aa) |
| | maf | Inhibitor of septum formation, Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (212 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (195 aa) |
| | GDI1446 | Conserved hypothetical protein. (239 aa) |
| | GDI1455 | Putative two-component sensor histidine kinase. (515 aa) |
| | GDI1487 | Putative carbohydrate kinase. (473 aa) |
| | GDI1490 | Putative carbohydrate kinase protein. (424 aa) |
| | GDI1503 | Dihydroorotate dehydrogenase. (426 aa) |
| | GDI1511 | Putative sensor histidine kinase. (461 aa) |
| | kdpD | Putative two-component sensor histidine kinase, sensor protein kdpD. (894 aa) |
| | GDI1577 | Conserved hypothetical protein. (878 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (346 aa) |
| | cobC | Alpha-ribazole phosphatase. (221 aa) |
| | fliI | Flagellum-specific ATP synthase. (455 aa) |
| | cheA | Putative chemotaxis protein cheA. (751 aa) |
| | pdhA | Putative pyruvate dehydrogenase E1 component subunit alpha. (321 aa) |
| | GDI3751 | Putative Glyoxalase/Bleomycin resistance protein/Dioxygenase. (256 aa) |
| | purK | Putative phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (382 aa) |
| | purE | Putative phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa) |
| | GDI1745 | Putative signal transduction histidine kinase. (603 aa) |
| | glpD-2 | Putative glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (564 aa) |
| | glpK-2 | Putative glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (499 aa) |
| | thiL | Putative thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (324 aa) |
| | glk | Glucokinase; Belongs to the bacterial glucokinase family. (322 aa) |
| | coaBC | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (563 aa) |
| | glmU | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (461 aa) |
| | thiS | Putative thiamine biosynthesis protein ThiS. (65 aa) |
| | thiG | Thiazole biosynthesis protein thiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (256 aa) |
| | thiE-2 | Thiamine-phosphate pyrophosphorylase. (202 aa) |
| | bacA | Putative undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (285 aa) |
| | tmk | Putative thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (215 aa) |
| | GDI1810 | Putative nucleoside 2-deoxyribosyltransferase. (198 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa) |
| | pgsA | Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferas; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (198 aa) |
| | moaD | Putative molybdopterin-converting factor subunit 1. (85 aa) |
| | moaE | Putative molybdopterin-converting factor subunit 2. (152 aa) |
| | nrdB | Putative ribonucleotide reductase small subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (353 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (253 aa) |
| | GDI1836 | Acetyl-CoA hydrolase. (506 aa) |
| | dxs-2 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (667 aa) |
| | glcK | Glucokinase protein. (305 aa) |
| | suhB-2 | Inositol-1-monophosphatase. (274 aa) |
| | moaA | Putative molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (338 aa) |
| | pgl-2 | Putative 6-phosphogluconolactonase. (414 aa) |
| | lysC | Aspartokinase protein; Belongs to the aspartokinase family. (441 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (382 aa) |
| | moeA | Putative molybdopterin biosynthesis protein moeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (401 aa) |
| | eno | Enolase protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (543 aa) |
| | tpiA | Putative triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (247 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (171 aa) |
| | phdA | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (363 aa) |
| | pdhB-2 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (448 aa) |
| | pdhC | Dihydrolipoamid acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (424 aa) |
| | GDI1950 | Putative CinA-like; Belongs to the CinA family. (165 aa) |
| | pgpA | Putative phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (159 aa) |
| | purB | Ptative adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (451 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (254 aa) |
| | purS | Putative phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to a [...] (80 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (233 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (737 aa) |
| | GDI1965 | Putative cardiolipin synthetase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (472 aa) |
| | surE | Putative 5'-nucleotidase surE. (133 aa) |
| | GDI1986 | Putative phosphoglycolate phosphatase. (235 aa) |
| | dht | D-hydantoinase protein (Dihydropyrimidinase) (DHPase). (475 aa) |
| | cdh | Putative CDP-diacylglycerol pyrophosphatase. (276 aa) |
| | ppk | Putative polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (764 aa) |
| | purM | Putative phosphoribosylformylglycinamidine cyclo-ligase. (316 aa) |
| | purN | Putative trifunctional purine biosynthetic protein adenosine-3; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (212 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | gpsA | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (320 aa) |
| | GDI2109 | Putative ubiquinone biosynthesis protein ubiB. (454 aa) |
| | argB | Putative acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (322 aa) |
| | GDI2140 | Conserved hypothetical protein. (282 aa) |
| | lpxA | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferas; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (297 aa) |
| | fabZ | (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (161 aa) |
| | lpxD | Putative UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferas; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (356 aa) |
| | dxr | Putative 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa) |
| | cdsA | Putative phosphatidate cytidylyltransferase; Belongs to the CDS family. (286 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa) |
| | spoT | Putative guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (778 aa) |
| | folK | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinas. (202 aa) |
| | pta | Putative phosphate acetyltransferase. (329 aa) |
| | dgoK | Putative 2-dehydro-3-deoxygalactonokinase. (316 aa) |
| | GDI2180 | Molybdopterin binding. (250 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa) |
| | aroKB | Putative bifunctional protein: shikimate kinase and 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (591 aa) |
| | GDI2186 | Thiaminase-2 protein. (234 aa) |
| | GDI2213 | Conserved protein. (393 aa) |
| | GDI2226 | Deoxyguanosinetriphosphate triphosphohydrolase-like protein; Belongs to the dGTPase family. Type 2 subfamily. (400 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa) |
| | mazG | Putative protein mazG. (263 aa) |
| | suhB-3 | Putative inositol-1-monophosphatase. (285 aa) |
| | ntrY | Putatie histidine kinase, nitrogen regulation protein ntrY. (738 aa) |
| | ntrB | Putative histidine kinase, nitrogen regulation protein ntrB. (369 aa) |
| | ispDF | IspD/ispF bifunctional enzyme; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (384 aa) |
| | GDI2275 | Putative signalling protein, GGDEF family. (700 aa) |
| | anmK | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (388 aa) |
| | coaA | Putative pantothenate kinase. (317 aa) |
| | cbbT | Putative transketolase; Belongs to the transketolase family. (705 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (407 aa) |
| | coaD | Putative phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (169 aa) |
| | GDI2340 | Putative chloramphenicol 3-O phosphotransferase. (186 aa) |
| | GDI2382 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (245 aa) |
| | GDI2416 | Putative glyoxylase I family protein. (138 aa) |
| | acsA | Putative acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (645 aa) |
| | GDI2504 | Putative 2-oxoglutarate dehydrogenase E1 component beta subunit. (311 aa) |
| | GDI2506 | Putative 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). (118 aa) |
| | GDI2511 | Putative small multidrug resistance protein. (102 aa) |
| | exoP | Putative succinoglycan biosynthesis transport protein exoP. (738 aa) |
| | GDI2568 | Putative signalling protein, GGDEF family. (694 aa) |
| | phoR | Putative phosphate regulon, two-component sensor histidine kinase, phoR. (402 aa) |
| | araB | Ribulokinase. (553 aa) |
| | xylB | Putative xylulose kinase. (492 aa) |
| | rbsK | Putative ribokinase. (292 aa) |
| | udp | Putative uridine phosphorylase. (260 aa) |
| | dapA-3 | Putative dihydrodipicolinate synthase; Belongs to the DapA family. (315 aa) |
| | dht-2 | Putative dihydropyrimidinase. (464 aa) |
| | GDI2785 | Putative metallophosphoesterase. (377 aa) |
| | GDI2791 | Conserved hypothetical protein. (343 aa) |
| | GDI2810 | Conserved hypothetical protein. (360 aa) |
| | GDI2880 | Conserved hypothetical protein. (354 aa) |
| | GDI2891 | Putative ubiquitin-activating enzyme. (585 aa) |
| | GDI2930 | Putative diacylglycerol kinase (DAG) catalytic domain protein. (323 aa) |
| | 2_085 | Unknown protein. (771 aa) |
| | suhB-4 | Inositol-1-monophosphatase. (262 aa) |
| | coaE | Putative dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (204 aa) |
| | fabZ-2 | Putative (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase. (159 aa) |
| | GDI3010 | Putative transketolase. (320 aa) |
| | GDI3011 | Putative transketolase. (250 aa) |
| | nnrD | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] (492 aa) |
| | GDI3069 | Putative nucleoside diphosphate. (322 aa) |
| | plsX | Putative fatty acid/phospholipid synthesis protein plsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (374 aa) |
| | GDI3079 | Putative sensor signal transduction histidine kinase. (467 aa) |
| | thrB | Putative homoserine kinase; Belongs to the pseudomonas-type ThrB family. (321 aa) |
| | ispH | Putative 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (355 aa) |
| | GDI3115 | Shikimate kinase. (208 aa) |
| | mtnK | Putative kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (437 aa) |
| | guaA | Gmp synthase [glutamine-hydrolyzing] (glutamin amidotransferase) (gmp synthetase); Catalyzes the synthesis of GMP from XMP. (562 aa) |
| | rbsK-2 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (316 aa) |
| | proB | Putative glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (382 aa) |
| | zwf-3 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (492 aa) |
| | lpxC | Putative UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (341 aa) |
| | pncA | Pyrazinamidase/nicotinamidase. (170 aa) |
| | gpt | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (168 aa) |
| | GDI3226 | Conserved hypothetical protein. (308 aa) |
| | pdxH | Putative pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (200 aa) |
| | cysC | Putative sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. (635 aa) |
| | kdtA | Putative 3-deoxy-D-manno-octulosonic-acid transferase. (435 aa) |
| | lpxK | Putative tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (327 aa) |
| | GDI3263 | Putative amidohydrolase. (458 aa) |
| | lpxB | Putative lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (388 aa) |
| | GDI3286 | Putative two-component sensor histidine kinase/response regulator hybrid protein. (621 aa) |
| | GDI3287 | Putative histidine kinase. (636 aa) |
| | cheA-2 | Putative chemotaxis protein cheA. (719 aa) |
| | GDI3298 | Putative acetyl transferase. (261 aa) |
| | psd | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (225 aa) |
| | pssA-2 | Putative CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (304 aa) |
| | cysQ | Inositol monophosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (265 aa) |
| | carA | Putative carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (467 aa) |
| | carB | Putative carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1084 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (216 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutas; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (516 aa) |
| | nudH | Putative (di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (167 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (219 aa) |
| | GDI3419 | Putative two-component sensor histidine kinase. (467 aa) |
| | cmk | Cytidylate kinase. (219 aa) |
| | GDI3470 | Conserved hypothetical protein; Belongs to the Nudix hydrolase family. (314 aa) |
| | GDI3484 | Polyphosphate kinase. (303 aa) |
| | GDI3486 | Conserved hyothetical protein; Belongs to the UPF0301 (AlgH) family. (207 aa) |
| | ppa | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (174 aa) |
| | purF | Aidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (517 aa) |
| | garS | Putative phosphoribosylamine--glycine ligase; Belongs to the GARS family. (412 aa) |
| | GDI3549 | Putative membrane protein. (375 aa) |
| | GDI3665 | Putative signalling protein, GGDEF family. (692 aa) |
| | GDI3706 | Putative phosphoesterase. (370 aa) |
| | GDI3725 | Two-component system, sensor histidine kinase. (421 aa) |
| | HypE | Conserved hypothetical protein. (328 aa) |
