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rpl39E rpl39E rpl31E rpl31E rps17E rps17E rps13P rps13P rps4P rps4P rps11P rps11P rpl18E rpl18E rpl13P rpl13P rps9P rps9P rps2P rps2P rpl7AE rpl7AE rpl24E rpl24E rpl21E rpl21E rps10p-2 rps10p-2 rrnAC0979 rrnAC0979 rpl11P rpl11P rpl1P rpl1P rpL12P rpL12P rps15P rps15P rps3AE rps3AE rps8E rps8E rpl15P rpl15P rpl30P rpl30P rps5P rps5P rpl18P rpl18P rpl19E rpl19E rps27E rps27E rpl32E rpl32E rpl6P rpl6P rps8P rps8P rpl5P rpl5P rps4E rps4E rpl24P rpl24P rpl14P rpl14P rps17P rps17P rpl29P rpl29P rps3P rps3P rpl22P rpl22P rps19P rps19P rpl2P rpl2P rpl23P rpl23P rpl4 rpl4 rpl3 rpl3 rpl37AE rpl37AE rpl15E rpl15E rps6E rps6E rpl10E-2 rpl10E-2 rps10p-1 rps10p-1 rps19E rps19E rps7P rps7P rps12P rps12P rps24E rps24E rps27AE rps27AE rpl40E rpl40E rpl44E rpl44E
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl39E50S ribosomal protein L39e; Binds to the 23S rRNA. Forms part of the polypeptide exit tunnel; Belongs to the eukaryotic ribosomal protein eL39 family. (50 aa)
rpl31E50S ribosomal protein L31e; Binds to the 23S rRNA. Located at the polypeptide exit tunnel on the outside of the subunit; Belongs to the eukaryotic ribosomal protein eL31 family. (92 aa)
rps17E30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (63 aa)
rps13P30S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (177 aa)
rps4P30S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (171 aa)
rps11P30S ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpl18E50S ribosomal protein L18e; Stabilizes the tertiary rRNA structure within the 23S rRNA domain (domain II) to which it binds; Belongs to the eukaryotic ribosomal protein eL18 family. (116 aa)
rpl13P50S ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit (By similarity). Binds to 23S rRNA. (145 aa)
rps9P30S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (132 aa)
rps2P30S ribosomal protein S2P. (267 aa)
rpl7AE50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (120 aa)
rpl24E50S ribosomal protein L24e; Binds to the 23S rRNA. (116 aa)
rpl21E50S ribosomal protein L21e; This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains. (96 aa)
rps10p-2Ribosomal protein S10p; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (138 aa)
rrnAC0979Putative nuclease. (726 aa)
rpl11P50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (162 aa)
rpl1P50S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa)
rpL12P50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (115 aa)
rps15P30S ribosomal protein S15P. (156 aa)
rps3AE30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (213 aa)
rps8E30S ribosomal protein S8e; Belongs to the eukaryotic ribosomal protein eS8 family. (123 aa)
rpl15P50S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (165 aa)
rpl30P50S ribosomal protein L30P; This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains. (154 aa)
rps5P30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (212 aa)
rpl18P50S ribosomal protein L18P; This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, where it forms part of the central protuberance and stabilizes the orientation of adjacent RNA domains. (187 aa)
rpl19E50S ribosomal protein L19e; Binds to the 23S rRNA. Located at the polypeptide exit tunnel on the outside of the subunit; Belongs to the eukaryotic ribosomal protein eL19 family. (149 aa)
rps27E30S ribosomal protein S27e. (57 aa)
rpl32E50S ribosomal protein L32E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL32 family. (241 aa)
rpl6P50S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
rps8P30S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rpl5P50S ribosomal protein L5P; This is 1 of 5 proteins that mediates the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains. Forms part of the central protuberance. Modeling places the A and P site tRNAs in close proximity to this protein; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. In the 70S ribosome it is thought to contact protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. (177 aa)
rps4E30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (234 aa)
rpl24P50S ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (120 aa)
rpl14P50S ribosomal protein L14P; Forms part of two intersubunit bridges in the 70S ribosome (By similarity). Binds to 23S rRNA; Belongs to the universal ribosomal protein uL14 family. (132 aa)
rps17PRibosomal protein S17p; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (112 aa)
rpl29P50S ribosomal protein L29P; Stabilizes the tertiary rRNA structure within the 23S rRNA domain (domain I) to which it binds. Located at the polypeptide exit tunnel on the outside of the subunit; Belongs to the universal ribosomal protein uL29 family. (71 aa)
rps3P30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (304 aa)
rpl22P50S ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (155 aa)
rps19P30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa)
rpl2P50S ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity). (240 aa)
rpl23P50S ribosomal protein L23P; Binds to a specific region on the 23S rRNA. Located at the polypeptide exit tunnel on the outside of the subunit; Belongs to the universal ribosomal protein uL23 family. (85 aa)
rpl450S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly (By similarity). Forms part of the polypeptide exit tunnel, in which it helps forms a bend with protein L22. Contacts the macrolide antibiotic spiramycin in the polypeptide exit tunnel; Belongs to the universal ribosomal protein uL4 family. (246 aa)
rpl350S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (338 aa)
rpl37AE50S ribosomal protein L37ae; Binds to the 23S rRNA. (116 aa)
rpl15E50S ribosomal protein L15e. (196 aa)
rps6E30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (129 aa)
rpl10E-250S ribosomal protein L10e; This is 1 of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains. Modeling places the A and P site tRNAs in close proximity to this protein. (177 aa)
rps10p-130S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa)
rps19E30S ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (153 aa)
rps7P30S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (206 aa)
rps12P30S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa)
rps24E30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (102 aa)
rps27AE30S ribosomal protein S27ae; Belongs to the eukaryotic ribosomal protein eS31 family. (44 aa)
rpl40E50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa)
rpl44E50S ribosomal protein L44E; Binds to the 23S rRNA. Binds deacetylated tRNA in the E site; when the tRNA binds a stretch of 7 amino acids are displaced to allow binding. (92 aa)
Your Current Organism:
Haloarcula marismortui
NCBI taxonomy Id: 272569
Other names: H. marismortui ATCC 43049, Haloarcula marismortui ATCC 43049, Haloarcula marismortui str. ATCC 43049, Haloarcula marismortui strain ATCC 43049
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