STRINGSTRING
malG malG malK malK dnaB dnaB uvrA uvrA KPN_04456 KPN_04456 KPN_04458 KPN_04458 KPN_04459 KPN_04459 rbsA-3 rbsA-3 groEL groEL groES groES groEL-2 groEL-2 KPN_04536 KPN_04536 mutL mutL ytfR ytfR mgtA mgtA KPN_04679 KPN_04679 KPN_04682 KPN_04682 KPN_04708 KPN_04708 KPN_04710 KPN_04710 sms sms yjjK yjjK dnaK dnaK hepA hepA yabJ yabJ secA secA hrpB hrpB metN metN phnE phnE KPN_00287 KPN_00287 phnC phnC gltL gltL secD secD secF secF clpP clpP clpX clpX lon lon mdlA mdlA mdlB mdlB KPN_00426 KPN_00426 KPN_00428 KPN_00428 KPN_00429 KPN_00429 htpG htpG copA copA rbsA-2 rbsA-2 KPN_00533 KPN_00533 KPN_00559 KPN_00559 KPN_00575 KPN_00575 KPN_00640 KPN_00640 gltL-2 gltL-2 kdpC kdpC kdpB kdpB kdpA kdpA modC modC KPN_00790 KPN_00790 uvrB uvrB rhlE rhlE dinG dinG glnQ glnQ potG potG potH potH potI potI artP artP clpA clpA cydC cydC cydD cydD ycaJ ycaJ msbA msbA hsdR hsdR ssuA ssuA uup uup ycbZ ycbZ helD helD KPN_00996 KPN_00996 mfd mfd potC potC potB potB potA potA KPN_01328 KPN_01328 metN-2 metN-2 dbpA dbpA KPN_01460 KPN_01460 paaD paaD hrpA hrpA KPN_01653 KPN_01653 KPN_01732 KPN_01732 KPN_01763 KPN_01763 KPN_01820 KPN_01820 KPN_01887 KPN_01887 KPN_01898 KPN_01898 ydcV ydcV ydcU ydcU KPN_02033 KPN_02033 KPN_02039 KPN_02039 ccmA ccmA KPN_02086 KPN_02086 KPN_02097 KPN_02097 KPN_02108 KPN_02108 KPN_02109 KPN_02109 btuD btuD ychF ychF minD minD fadD fadD yoaA yoaA znuC znuC ruvB ruvB ruvA ruvA araG araG araF araF yecC yecC KPN_02485 KPN_02485 yegD yegD mrp mrp mglA mglA yejH yejH yojI yojI gyrA gyrA hisP hisP cysA cysA cysW cysW cysU cysU eutJ eutJ hscA hscA srmB srmB clpB clpB KPN_02947 KPN_02947 KPN_02977 KPN_02977 recA recA mutS mutS KPN_03141 KPN_03141 KPN_03145 KPN_03145 cbiP cbiP cibB cibB recD recD recB recB recC recC aas aas KPN_03256 KPN_03256 KPN_03258 KPN_03258 parC parC parE parE ego ego deaD deaD secG secG hflB hflB yhcM yhcM ugpC ugpC zntA zntA nikD nikD nikE nikE yhjR-2 yhjR-2 xylG xylG recG recG phnU phnU gyrB gyrB KPN_04116 KPN_04116 pstB pstB atpD atpD atpA atpA yieN yieN rbsA rbsA KPN_04209 KPN_04209 hslU hslU priA priA btuB btuB rep rep rhlB rhlB rho rho uvrD uvrD recQ recQ malF malF
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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malGMaltose transport protein (ABC superfamily, membrane). (296 aa)
malKATP-binding component of transport system for maltose; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (369 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (471 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (941 aa)
KPN_04456Putrescine/spermidine ABC transporter ATPase. (353 aa)
KPN_04458Spermidine/putrescine ABC transporter membrane component. (277 aa)
KPN_04459Putative ABC transporter permease protein. (285 aa)
rbsA-3Putative ABC transporter; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (506 aa)
groELChaperonin GroEL. (318 aa)
groESCo-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (97 aa)
groEL-2Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (548 aa)
KPN_04536Putative secretion ATPase. (707 aa)
mutLDNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (619 aa)
ytfRPutative sugar transport protein (ABC superfamily, atp_bind). (500 aa)
mgtAMg2+ transport ATPase, P-type 1. (902 aa)
KPN_04679Putative ABC transporter; Belongs to the ABC transporter superfamily. (357 aa)
KPN_04682Putative SN-glycerol-3-phosphate transport system permease. (294 aa)
KPN_04708Putative ATP-dependent helicase. (1046 aa)
KPN_04710Hypothetical protein. (1332 aa)
smsProbable ATP-dependent protease; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (460 aa)
yjjKPutative ATP-binding component of a transport system. (548 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (638 aa)
hepAATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (968 aa)
yabJPutative ATP-binding component of a transport system; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (233 aa)
secATranslocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (901 aa)
hrpBHelicase, ATP-dependent. (809 aa)
metND- and L-methionine transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
phnEMembrane channel protein component of Pn transporter. (294 aa)
KPN_00287Hypothetical protein. (290 aa)
phnCATP-binding component of phosphonate transport; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (287 aa)
gltLATP-binding protein of glutamate/aspartate transport system. (272 aa)
secDProtein export protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (604 aa)
secFProtein export protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (323 aa)
clpPATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (194 aa)
clpXATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (424 aa)
lonDNA-binding ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (784 aa)
mdlAATP-binding component of a transport system. (590 aa)
mdlBPutative ATP-binding component of a transport system. (592 aa)
KPN_00426ABC transporter; Belongs to the ABC transporter superfamily. (371 aa)
KPN_00428Maltose transport protein (ABC superfamily, membrane). (435 aa)
KPN_00429Putative binding-protein-dependent transport systems inner membrane component. (283 aa)
htpGHeat shock protein 90; Molecular chaperone. Has ATPase activity. (624 aa)
copACu(I)-translocating P-type ATPase. (851 aa)
rbsA-2Putative ABC transporter; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (494 aa)
KPN_00533Hypothetical protein. (121 aa)
KPN_00559Mg2+ transport ATPase, P-type 1. (904 aa)
KPN_00575Putative ABC transporter. (253 aa)
KPN_00640Putative ABC-type sugar transport system, ATPase component. (516 aa)
gltL-2ATP-binding protein of glutamate/aspartate transport system. (241 aa)
kdpCPotassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (191 aa)
kdpBPotassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa)
kdpAPotassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (559 aa)
modCATP-binding component of molybdate transport; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (353 aa)
KPN_00790Putative cation transport protein. (895 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (673 aa)
rhlEPutative ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (451 aa)
dinGLexA-regulated (SOS) repair enzyme; DNA-dependent ATPase and 5'-3' DNA helicase. (718 aa)
glnQGlutamine ABC transporter ATP-binding component. (240 aa)
potGATP-binding component of putrescine transport system; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (393 aa)
potHPutrescine transport protein (ABC superfamily, membrane). (317 aa)
potIPutrescine transport protein (ABC superfamily, membrane). (281 aa)
artPATP-binding component of 3rd arginine transport system. (242 aa)
clpAATP-binding component of serine protease; Belongs to the ClpA/ClpB family. (759 aa)
cydCATP-binding component of cytochrome-related transport. (573 aa)
cydDATP-binding component of cytochrome-related transport, Zn sensitive. (588 aa)
ycaJPutative polynucleotide enzyme. (447 aa)
msbAATP-binding transport protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa)
hsdRPutative type III restriction enzyme, res subunit. (1085 aa)
ssuAPutative alkanesulfonate transport protein (ABC superfamily, peri_bind). (320 aa)
uupPutative ATP-binding component of a transport system. (635 aa)
ycbZPutative ATP-dependent protease. (585 aa)
helDDNA helicase IV. (684 aa)
KPN_00996Putative ABC transporter, transmembrane region. (715 aa)
mfdTranscription-repair ATP-dependent coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1152 aa)
potCSpermidine/putrescine ABC transporter membrane component. (261 aa)
potBSpermidine/putrescine ABC transporter membrane component. (285 aa)
potAPutrescine/spermidine ABC transporter ATPase; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa)
KPN_01328Putative protease; Belongs to the ClpA/ClpB family. (866 aa)
metN-2Putative ABC transporter; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (341 aa)
dbpAATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. (457 aa)
KPN_01460Putative ATP-binding component of a transport system. (506 aa)
paaDPhenylacetic acid degradation protein. (165 aa)
hrpAHelicase, ATP-dependent. (1300 aa)
KPN_01653D- and L-methionine transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. (263 aa)
KPN_01732Putative ABC transporter. (260 aa)
KPN_01763ATP-binding component of histidine transport. (245 aa)
KPN_01820Putative ATPase. (328 aa)
KPN_01887Putative ABC transporter substrate binding protein. (234 aa)
KPN_01898Putative ATP-binding component of a transport system. (259 aa)
ydcVPutative ABC transporter permease protein. (268 aa)
ydcUPutative ABC transporter permease protein. (309 aa)
KPN_02033ABC transporter, periplasmic binding component-related protein. (313 aa)
KPN_02039ABC superfamily transport, peri_bind). (327 aa)
ccmAATP binding protein of heme exporter A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (207 aa)
KPN_02086Putative ABC transporter; Belongs to the ABC transporter superfamily. (356 aa)
KPN_02097Putative ABC transporter. (240 aa)
KPN_02108Taurine transport protein (ABC superfamily, peri_bind). (345 aa)
KPN_02109Putatove ABC-type transport systems, periplasmic components. (312 aa)
btuDVitamin B12-transporter ATPase; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa)
ychFPutative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa)
minDCell division inhibitor, a membrane ATPase, activates minC. (270 aa)
fadDacyl-CoA synthase. (572 aa)
yoaAPutative ATP-dependent helicase, SOS repair. (636 aa)
znuCHigh-affinity zinc uptake system ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (250 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa)
ruvAHolliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa)
araGATP-binding component of high-affinity L-arabinose transport system; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family. (504 aa)
araFL-arabinose-binding periplasmic protein. (326 aa)
yecCPutative ATP-binding component of a transport system. (250 aa)
KPN_02485O-antigen export - NBD component. (443 aa)
yegDPutative heat shock protein. (456 aa)
mrpPutative ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (354 aa)
mglAATP-binding component of methyl-galactoside transport and galactose taxis. (491 aa)
yejHPutative ATP-dependent helicase. (585 aa)
yojIPutative ATP-binding component of a transport system. (547 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (877 aa)
hisPATP-binding component of histidine transport. (257 aa)
cysAATP-binding component of sulfate permease A protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (364 aa)
cysWSulfate transport system permease W protein. (291 aa)
cysUSulfate, thiosulfate transport system permease T protein; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (277 aa)
eutJEthanolamine utilization protein. (281 aa)
hscAChaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. (616 aa)
srmBATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (443 aa)
clpBATP-dependent protease, Hsp 100; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (857 aa)
KPN_02947Hypothetical protein. (242 aa)
KPN_02977Glutamine ABC transporter ATP-binding component. (506 aa)
recARecombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (352 aa)
mutSDNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (853 aa)
KPN_03141Putative ABC-type transport protein. (313 aa)
KPN_03145Putative D- and L-methionine transport protein (ABC superfamily, atp_bind). (196 aa)
cbiPHypothetical protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (507 aa)
cibBHypothetical protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (319 aa)
recDDNA helicase, ATP-dependent dsDNA/ssDNA exonuclease V subunit, ssDNA endonuclease; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the [...] (614 aa)
recBDNA helicase, ATP-dependent dsDNA/ssDNA exonuclease V subunit, ssDNA endonuclease; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the [...] (1178 aa)
recCDNA helicase, ATP-dependent dsDNA/ssDNA exonuclease V subunit, ssDNA endonuclease; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the [...] (1109 aa)
aas2-acyl-glycerophospho-ethanolamine acyltransferase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1. (719 aa)
KPN_03256Putative inner membrane permease of oligogalacturonide ABC transporter. (296 aa)
KPN_03258Putative ATP-binding component of a transport system; Belongs to the ABC transporter superfamily. (375 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (752 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (631 aa)
egoPutative ATP-binding component of a transport system; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (By similarity). (496 aa)
deaDCold-shock DeaD box ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (643 aa)
secGProtein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (109 aa)
hflBATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (644 aa)
yhcMPutative ATPase; Reduces the stability of FtsZ polymers in the presence of ATP. (375 aa)
ugpCATP-binding component of sn-glycerol 3-phosphate transport system; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (356 aa)
zntAPb/Cd/Zn/Hg transporting ATPase (P-type ATPase family). (736 aa)
nikDATP-binding protein of nickel transport system. (254 aa)
nikEATP-binding protein of nickel transport system. (263 aa)
yhjR-2Hypothetical protein. (62 aa)
xylGD-xylose transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. (513 aa)
recGDNA helicase, ATP-dependent resolution of Holliday junctions, branch migration; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (693 aa)
phnU2-aminoethylphosphonate transporter, membrane component. (287 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (804 aa)
KPN_04116Hypothetical protein. (249 aa)
pstBATP-binding component of high-affinity phosphate-specific transport system; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (257 aa)
atpDATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (460 aa)
atpAATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa)
yieNPutative 2-component regulator. (499 aa)
rbsAATP-binding component of D-ribose high-affinity transport system; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa)
KPN_04209Putative ABC transporter. (503 aa)
hslUATP-dependent protease ATP-binding subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (444 aa)
priAPrimosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (731 aa)
btuBOuter membrane porin: vitamin B12/cobalamin transport, receptor for E colicins, bacteriophage BF23; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (618 aa)
repRep helicase, a single-stranded DNA-dependent ATPase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (673 aa)
rhlBATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (421 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa)
uvrDDNA-dependent ATPase I and helicase II. (720 aa)
recQATP-dependent DNA helicase. (608 aa)
malFMaltose transport protein (ABC superfamily, membrane). (514 aa)
Your Current Organism:
Klebsiella pneumoniae MGH78578
NCBI taxonomy Id: 272620
Other names: K. pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae MCG 78578, Klebsiella pneumoniae str. MCG 78578, Klebsiella pneumoniae subsp. pneumoniae ATCC 700721, Klebsiella pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae subsp. pneumoniae str. MGH 78578, Klebsiella pneumoniae subsp. pneumoniae strain MGH 78578
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