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| | yjjK | Putative ATP-binding component of a transport system. (548 aa) |
| | hepA | ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (968 aa) |
| | yabJ | Putative ATP-binding component of a transport system; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (233 aa) |
| | secA | Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (901 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa) |
| | hofB | Putative integral membrane protein; Involved in biogenesis of fimbriae (type IV pilin), protein transport, DNA uptake. (461 aa) |
| | yadG | Putative ATP-binding component of a transport system. (308 aa) |
| | hrpB | Helicase, ATP-dependent. (809 aa) |
| | pulE | Pullulanase E protein; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (497 aa) |
| | fhuC | ATP-binding component of hydroxymate-dependent iron transport. (265 aa) |
| | metN | D- and L-methionine transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa) |
| | phnC | ATP-binding component of phosphonate transport; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (287 aa) |
| | gltL | ATP-binding protein of glutamate/aspartate transport system. (272 aa) |
| | livF | ATP-binding component of leucine transport. (231 aa) |
| | livG | ATP-binding component of high-affinity branched-chain amino acid transport system. (260 aa) |
| | tauB | Taurine ATP-binding component of a transport system; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family. (255 aa) |
| | aroL | Shikimate kinase II; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (177 aa) |
| | sbcC | ATP-dependent dsDNA exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SMC family. SbcC subfamily. (1045 aa) |
| | clpX | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (424 aa) |
| | lon | DNA-binding ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (784 aa) |
| | mdlA | ATP-binding component of a transport system. (590 aa) |
| | mdlB | Putative ATP-binding component of a transport system. (592 aa) |
| | KPN_00426 | ABC transporter; Belongs to the ABC transporter superfamily. (371 aa) |
| | dnaX | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (635 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | ybbL | Putative ATP-binding component of a transport system. (225 aa) |
| | ybbA | Putative ATP-binding component of a transport system. (228 aa) |
| | rbsA-2 | Putative ABC transporter; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (494 aa) |
| | KPN_00518 | Putative ABC transporter. (265 aa) |
| | KPN_00546 | Putative inner membrane protein. (909 aa) |
| | KPN_00567 | Putative ABC transporter; Belongs to the ABC transporter superfamily. (345 aa) |
| | KPN_00568 | Putative ABC transport system ATP-binding protein; Belongs to the ABC transporter superfamily. (336 aa) |
| | KPN_00575 | Putative ABC transporter. (253 aa) |
| | KPN_00578 | Putative ATP-binding component of a transport system. (234 aa) |
| | KPN_00579 | Putative ABC transporter. (278 aa) |
| | KPN_00598 | Putative ABC transporter. (508 aa) |
| | fepC | ATP-binding component of ferric enterobactin transport. (264 aa) |
| | KPN_00622 | Putative ABC transporter. (500 aa) |
| | KPN_00640 | Putative ABC-type sugar transport system, ATPase component. (516 aa) |
| | holA | DNA polymerase III subunit delta. (344 aa) |
| | gltL-2 | ATP-binding protein of glutamate/aspartate transport system. (241 aa) |
| | ybeZ | Putative ATP-binding protein in pho regulon. (348 aa) |
| | kdpD | Sensor for high-affinity potassium transport system. (895 aa) |
| | modF | ATP-binding component of molybdate transport system. (490 aa) |
| | modC | ATP-binding component of molybdate transport; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (353 aa) |
| | bioD | Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (240 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (673 aa) |
| | ybhF | Putative ATP-binding component of a transport system. (579 aa) |
| | rhlE | Putative ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (451 aa) |
| | dinG | LexA-regulated (SOS) repair enzyme; DNA-dependent ATPase and 5'-3' DNA helicase. (718 aa) |
| | glnQ | Glutamine ABC transporter ATP-binding component. (240 aa) |
| | ybiT | Putative ATP-binding component of a transport system. (522 aa) |
| | yliA | Putative ATP-binding component of a transport system; Belongs to the ABC transporter superfamily. (619 aa) |
| | potG | ATP-binding component of putrescine transport system; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (393 aa) |
| | artP | ATP-binding component of 3rd arginine transport system. (242 aa) |
| | ybjD | Conserved protein, nucleotide triphosphate hydrolase domain. (552 aa) |
| | macB | Macrolide transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (646 aa) |
| | clpA | ATP-binding component of serine protease; Belongs to the ClpA/ClpB family. (759 aa) |
| | cydC | ATP-binding component of cytochrome-related transport. (573 aa) |
| | cydD | ATP-binding component of cytochrome-related transport, Zn sensitive. (588 aa) |
| | ftsK | Cell division protein. (1417 aa) |
| | ycaJ | Putative polynucleotide enzyme. (447 aa) |
| | cmk | Cytidylate kinase. (227 aa) |
| | msbA | ATP-binding transport protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (326 aa) |
| | mukB | Condesin subunit B; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1482 aa) |
| | hsdR | Putative type III restriction enzyme, res subunit. (1085 aa) |
| | ssuB | Putative ABC transporter; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system. (257 aa) |
| | uup | Putative ATP-binding component of a transport system. (635 aa) |
| | ycbZ | Putative ATP-dependent protease. (585 aa) |
| | sulA | Suppressor of lon; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (169 aa) |
| | helD | DNA helicase IV. (684 aa) |
| | KPN_00996 | Putative ABC transporter, transmembrane region. (715 aa) |
| | phoH | PhoB-dependent, ATP-binding pho regulon component. (262 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa) |
| | holB | DNA polymerase III subunit delta. (334 aa) |
| | mfd | Transcription-repair ATP-dependent coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1152 aa) |
| | ycfV | Putative ATP-binding component of a transport system; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (233 aa) |
| | potA | Putrescine/spermidine ABC transporter ATPase; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa) |
| | yeaG | Hypothetical protein. (644 aa) |
| | ynjD | Putative ATP-binding component of a transport system. (210 aa) |
| | btuR | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (196 aa) |
| | sapF | Peptide transport protein (ABC superfamily, atp_bind). (269 aa) |
| | sapD | Peptide transport protein (ABC superfamily, atp_bind); Belongs to the ABC transporter superfamily. (330 aa) |
| | pspF | Psp operon transcriptional activator. (329 aa) |
| | tyrR | Transcriptional regulation of aroF, aroG, tyrA and aromatic amino acid transport. (513 aa) |
| | KPN_01328 | Putative protease; Belongs to the ClpA/ClpB family. (866 aa) |
| | metN-2 | Putative ABC transporter; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (341 aa) |
| | dbpA | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. (457 aa) |
| | KPN_01391 | Hypothetical protein. (249 aa) |
| | KPN_01413 | Hypothetical protein. (434 aa) |
| | KPN_01460 | Putative ATP-binding component of a transport system. (506 aa) |
| | hrpA | Helicase, ATP-dependent. (1300 aa) |
| | bioD-2 | Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (231 aa) |
| | KPN_01619 | ATP-binding component of high-affinity branched-chain amino acid transport system. (265 aa) |
| | KPN_01620 | ATP-binding component of leucine transport. (140 aa) |
| | KPN_01653 | D- and L-methionine transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. (263 aa) |
| | pgtA | Phosphoglycerate transport: activator. (416 aa) |
| | KPN_01732 | Putative ABC transporter. (260 aa) |
| | KPN_01763 | ATP-binding component of histidine transport. (245 aa) |
| | KPN_01800 | Putative ABC transporter. (242 aa) |
| | KPN_01820 | Putative ATPase. (328 aa) |
| | KPN_01850 | Putative ATP-binding component of a transport system. (571 aa) |
| | KPN_01857 | Putative ATP-binding component of a transport system; Belongs to the ABC transporter superfamily. (538 aa) |
| | KPN_01862 | Hypothetical protein. (274 aa) |
| | KPN_01887 | Putative ABC transporter substrate binding protein. (234 aa) |
| | KPN_01898 | Putative ATP-binding component of a transport system. (259 aa) |
| | KPN_01904 | Hypothetical protein. (183 aa) |
| | ydcT | Putative ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (337 aa) |
| | KPN_02022 | Putative ABC transport system ATP-binding protein; Belongs to the ABC transporter superfamily. (326 aa) |
| | KPN_02023 | ATP-binding protein of oligopeptide ABC transport system; Belongs to the ABC transporter superfamily. (323 aa) |
| | KPN_02040 | Putative ABC transporter, ATP-binding protein. (276 aa) |
| | ccmA | ATP binding protein of heme exporter A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (207 aa) |
| | KPN_02086 | Putative ABC transporter; Belongs to the ABC transporter superfamily. (356 aa) |
| | KPN_02097 | Putative ABC transporter. (240 aa) |
| | KPN_02104 | ATP-binding component of ferric enterobactin transport. (273 aa) |
| | KPN_02106 | Putative ABC-type transport system, ATPase component. (257 aa) |
| | KPN_02126 | Putative ABC transporter ATP-binding protein. (249 aa) |
| | sufC | Putative ATP-binding component of a transport system. (248 aa) |
| | KPN_02151 | ATP-binding component of citrate-dependent iron(III) transport protein. (253 aa) |
| | btuD | Vitamin B12-transporter ATPase; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa) |
| | oppF | ATP-binding protein of oligopeptide ABC transport system; Belongs to the ABC transporter superfamily. (334 aa) |
| | oppD | Oligopeptide transporter ATP-binding component; Belongs to the ABC transporter superfamily. (337 aa) |
| | tdk | Thymidine kinase. (175 aa) |
| | nasD | Putative nitrate transport protein nasD. (262 aa) |
| | ychF | Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa) |
| | livF-2 | ATP-binding component of leucine transport. (239 aa) |
| | livG-2 | ATP-binding component of high-affinity branched-chain amino acid transport system. (291 aa) |
| | minD | Cell division inhibitor, a membrane ATPase, activates minC. (270 aa) |
| | yoaA | Putative ATP-dependent helicase, SOS repair. (636 aa) |
| | znuC | High-affinity zinc uptake system ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (250 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa) |
| | araG | ATP-binding component of high-affinity L-arabinose transport system; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family. (504 aa) |
| | yecC | Putative ATP-binding component of a transport system. (250 aa) |
| | fusA | Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (700 aa) |
| | KPN_02485 | O-antigen export - NBD component. (443 aa) |
| | wzc | Tyrosine autokinase. (720 aa) |
| | udk | Uridine kinase. (213 aa) |
| | KPN_02534 | Dipeptide transport protein (ABC superfamily, atp_bind). (257 aa) |
| | KPN_02535 | Dipeptide transport protein (ABC superfamily, atp_bind). (280 aa) |
| | mrp | Putative ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (354 aa) |
| | yehX | Putative ATP-binding component of a transport system. (315 aa) |
| | mglA | ATP-binding component of methyl-galactoside transport and galactose taxis. (491 aa) |
| | yeiR | Putative enzyme. (325 aa) |
| | KPN_04882 | Putative prophage large terminase protein. (589 aa) |
| | yejF | Putative ATP-binding component of a transport system; Belongs to the ABC transporter superfamily. (529 aa) |
| | yejH | Putative ATP-dependent helicase. (585 aa) |
| | yojI | Putative ATP-binding component of a transport system. (547 aa) |
| | pta | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (710 aa) |
| | hisP | ATP-binding component of histidine transport. (257 aa) |
| | cysA | ATP-binding component of sulfate permease A protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (364 aa) |
| | eutP | Putative ethanolamine utilization protein; Belongs to the EutP/PduV family. (159 aa) |
| | ypfI | Putative acyl-CoA N-acyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (667 aa) |
| | hda | DNA replication initiation factor; Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity); Belongs to the DnaA family. HdA subfamily. (225 aa) |
| | yfgK | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (492 aa) |
| | yfhA | Putative 2-component transcriptional regulator. (445 aa) |
| | era | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (301 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa) |
| | srmB | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (443 aa) |
| | clpB | ATP-dependent protease, Hsp 100; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (857 aa) |
| | ffh | 4.5S-RNP protein, GTP-binding export factor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual [...] (454 aa) |
| | recN | Protein used in recombination and DNA repair; May be involved in recombinational repair of damaged DNA. (553 aa) |
| | KPN_02945 | Hypothetical protein. (1490 aa) |
| | KPN_02977 | Glutamine ABC transporter ATP-binding component. (506 aa) |
| | prpR | Putative helix-turn-helix, Fis-type. (595 aa) |
| | proV | ATP-binding component of transport system for glycine, betaine and proline. (400 aa) |
| | recA | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (352 aa) |
| | KPN_03035 | Putative ABC transporter ATP-binding protein. (236 aa) |
| | ygaA | Anaerobic nitric oxide reductase transcription regulator; Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54. (516 aa) |
| | hypB | Guanine-nucleotide binding protein; Functions as nickel donor for large subunit of hydrogenase 3. (290 aa) |
| | fhlA | Transcriptional activator for fdhF, hyc and hyp operons. (685 aa) |
| | sitB | Iron transporter: fur regulated. (273 aa) |
| | hmuV | ATP-binding component of hydroxymate-dependent iron transport; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. (259 aa) |
| | mutS | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (853 aa) |
| | cysC | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (201 aa) |
| | cysN | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (475 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) |
| | KPN_03145 | Putative D- and L-methionine transport protein (ABC superfamily, atp_bind). (196 aa) |
| | KPN_03148 | Putative transcriptional regulator. (647 aa) |
| | cobU | Bifunctional cobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (181 aa) |
| | cbiP | Hypothetical protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (507 aa) |
| | cbiO | Hypothetical protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. (274 aa) |
| | cbiA | Hypothetical protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (484 aa) |
| | pduV | Propanediol utilization; Belongs to the EutP/PduV family. (146 aa) |
| | recD | DNA helicase, ATP-dependent dsDNA/ssDNA exonuclease V subunit, ssDNA endonuclease; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the [...] (614 aa) |
| | recB | DNA helicase, ATP-dependent dsDNA/ssDNA exonuclease V subunit, ssDNA endonuclease; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the [...] (1178 aa) |
| | recC | DNA helicase, ATP-dependent dsDNA/ssDNA exonuclease V subunit, ssDNA endonuclease; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the [...] (1109 aa) |
| | KPN_03258 | Putative ATP-binding component of a transport system; Belongs to the ABC transporter superfamily. (375 aa) |
| | yggR | Hypothetical protein. (326 aa) |
| | ureG | Urease accessory protein ureG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (205 aa) |
| | dhaR | Glycerol metabolism operon regulatory protein. (615 aa) |
| | ego | Putative ATP-binding component of a transport system; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (By similarity). (496 aa) |
| | deaD | Cold-shock DeaD box ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (643 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (896 aa) |
| | hflB | ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (644 aa) |
| | yhbZ | Putative GTP-binding factor; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (392 aa) |
| | yrbF | Putative ATP-binding component of a transport system. (290 aa) |
| | yhbG | Putative ATP-binding component of a transport system. (241 aa) |
| | yhbJ | Hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. (284 aa) |
| | yhcM | Putative ATPase; Reduces the stability of FtsZ polymers in the presence of ATP. (375 aa) |
| | tuf | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | fusA-2 | Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (704 aa) |
| | yheS | Putative ATP-binding component of a transport system. (634 aa) |
| | prkB | Probable phosphoribulokinase. (289 aa) |
| | aroK | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | feoB | Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (772 aa) |
| | malT | Transcriptional regulator MalT; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box. (901 aa) |
| | gntK | Gluconate kinase 2 in GNT I system, thermoresistant. (191 aa) |
| | ugpC | ATP-binding component of sn-glycerol 3-phosphate transport system; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (356 aa) |
| | livF-3 | ATP-binding component of leucine transport; Belongs to the ABC transporter superfamily. (237 aa) |
| | livG-3 | ATP-binding component of high-affinity branched-chain amino acid transport system. (255 aa) |
| | ftsE | ATP-binding component of a membrane-associated complex involved in cell division; Part of the ABC transporter FtsEX involved in cellular division. (222 aa) |
| | ftsY | Cell division membrane protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (507 aa) |
| | nikD | ATP-binding protein of nickel transport system. (254 aa) |
| | nikE | ATP-binding protein of nickel transport system. (263 aa) |
| | yhjQ | Hypothetical protein. (243 aa) |
| | KPN_03894 | Putative ATPase involved in chromosome partitioning. (267 aa) |
| | dppF | Dipeptide transport protein (ABC superfamily, atp_bind); Belongs to the ABC transporter superfamily. (337 aa) |
| | dppD | Dipeptide transport protein (ABC superfamily, atp_bind); Belongs to the ABC transporter superfamily. (327 aa) |
| | KPN_03920 | Putative ATP-binding component of a transport system. (539 aa) |
| | xylG | D-xylose transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. (513 aa) |
| | selB | selenocysteinyl-tRNA-specific translation factor. (613 aa) |
| | KPN_03986 | Putative ABC-type multidrug transport system, ATPase component. (305 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | recG | DNA helicase, ATP-dependent resolution of Holliday junctions, branch migration; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (693 aa) |
| | phnT | 2-aminoethylphosphonate transporter,ATPase component; Belongs to the ABC transporter superfamily. (370 aa) |
| | recF | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (357 aa) |
| | dnaA | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (444 aa) |
| | trmE | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (454 aa) |
| | KPN_04116 | Hypothetical protein. (249 aa) |
| | pstB | ATP-binding component of high-affinity phosphate-specific transport system; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (257 aa) |
| | atpD | ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (460 aa) |
| | atpA | ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa) |
| | yieN | Putative 2-component regulator. (499 aa) |
| | rbsA | ATP-binding component of D-ribose high-affinity transport system; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa) |
| | mobB | Molybdopterin-guanine dinucleotide biosynthesis protein B. (126 aa) |
| | yihA | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (210 aa) |
| | glnG | Response regulator for gln (sensor glnL) (nitrogen regulator I, NRI); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (469 aa) |
| | bipA | GTP-binding elongation factor family protein. (607 aa) |
| | KPN_04198 | Putative serine protease. (197 aa) |
| | KPN_04209 | Putative ABC transporter. (503 aa) |
| | hslU | ATP-dependent protease ATP-binding subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (444 aa) |
| | priA | Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (731 aa) |
| | yifB | Putative 2-component regulator. (506 aa) |
| | rep | Rep helicase, a single-stranded DNA-dependent ATPase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (673 aa) |
| | rhlB | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (421 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa) |
| | uvrD | DNA-dependent ATPase I and helicase II. (720 aa) |
| | recQ | ATP-dependent DNA helicase. (608 aa) |
| | coaA | Pantothenate kinase. (318 aa) |
| | zraR | Response regulator in two-component reguatory system with ZraS, regulates zraP expression (EBP family). (443 aa) |
| | malK | ATP-binding component of transport system for maltose; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (369 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (471 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (941 aa) |
| | KPN_04456 | Putrescine/spermidine ABC transporter ATPase. (353 aa) |
| | rbsA-3 | Putative ABC transporter; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (506 aa) |
| | phnN | ATP-binding component of phosphonate transport; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (187 aa) |
| | phnL | ATP-binding component of phosphonate transport. (226 aa) |
| | phnK | ATP-binding component of phosphonate transport. (252 aa) |
| | KPN_04536 | Putative secretion ATPase. (707 aa) |
| | yjeQ | Ribosome-associated GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (353 aa) |
| | yjeE | Putative enzyme. (153 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (316 aa) |
| | hflX | GTP - binding subunit of protease specific for phage lambda cII repressor; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (426 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa) |
| | ytfR | Putative sugar transport protein (ABC superfamily, atp_bind). (500 aa) |
| | yjgR | Putative enzyme contains P-loop containing nucleotide triphosphate hydrolase domain. (505 aa) |
| | KPN_04679 | Putative ABC transporter; Belongs to the ABC transporter superfamily. (357 aa) |
| | KPN_04708 | Putative ATP-dependent helicase. (1046 aa) |
| | KPN_04710 | Hypothetical protein. (1332 aa) |
| | KPN_04750 | Putative ABC-type multidrug transport system, ATPase component; Permease component of an ABC-transporter. (914 aa) |
| | KPN_04754 | Putative bacterial inner-membrane translocator. (494 aa) |
| | yjiA | Putative synthesis protein. (322 aa) |
| | KPN_04801 | Putative NtrC family transcriptional regulators, ATPase domain. (921 aa) |
| | dnaC | Chromosome replication; initiation and chain elongation. (247 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | sms | Probable ATP-dependent protease; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (460 aa) |
| | nadR | Nicotinamide-nucleotide adenylyltransferase. (410 aa) |
