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rpsO | 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa) | ||||
rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (133 aa) | ||||
rplM | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) | ||||
fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (315 aa) | ||||
rpsD | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa) | ||||
rpsM | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (118 aa) | ||||
rpmD | 50S ribosomal protein L30. (59 aa) | ||||
rplX | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (104 aa) | ||||
rplN | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa) | ||||
rpsQ | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) | ||||
rpsC | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (232 aa) | ||||
rplB | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa) | ||||
tuf | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) | ||||
rpsL | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. (124 aa) | ||||
aroK | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) | ||||
glyQ | glycyl-tRNA synthetase alpha subunit. (303 aa) | ||||
gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) | ||||
tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa) | ||||
metJ | Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. (105 aa) | ||||
ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (491 aa) | ||||
nusG | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination [...] (181 aa) | ||||
rplJ | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (165 aa) | ||||
pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (549 aa) | ||||
trpR | Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. (109 aa) | ||||
deoD | Purine nucleoside phosphorylase. (230 aa) | ||||
carB | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1074 aa) | ||||
araA | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (500 aa) | ||||
rpsB | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (236 aa) | ||||
proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa) | ||||
aroL | Shikimate kinase II; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (177 aa) | ||||
nusB | Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (139 aa) | ||||
ybaK | Hypothetical protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (159 aa) | ||||
lysS | lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) | ||||
ybeB | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (105 aa) | ||||
galM | Galactose-1-epimerase (mutarotase); Converts alpha-aldose to the beta-anomer. (347 aa) | ||||
galK | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (383 aa) | ||||
pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (336 aa) | ||||
rpmF | 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (57 aa) | ||||
tktA | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa) | ||||
potD | Spermidine/putrescine ABC transporter periplasmic substrate-binding component; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family. (348 aa) | ||||
trmU | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. (388 aa) | ||||
selD | Selenophosphate synthetase; Synthesizes selenophosphate from selenide and ATP. (347 aa) | ||||
topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (865 aa) | ||||
pspA | Phage shock protein, inner membrane protein. (227 aa) | ||||
tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (428 aa) | ||||
mhpR | Transcriptional activator for 3-hydroxyphenylpropionate degradation (IclR family). (270 aa) | ||||
pykF | Pyruvate kinase; Belongs to the pyruvate kinase family. (470 aa) | ||||
narL | Pleiotrophic regulation of anaerobic respiration; Response regulator for nar, frd, dms and tor genes. (216 aa) | ||||
prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa) | ||||
pykA | Pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa) | ||||
yebC | Hypothetical protein. (246 aa) | ||||
aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (595 aa) | ||||
hisC | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (353 aa) | ||||
mrp | Putative ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (354 aa) | ||||
metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (677 aa) | ||||
rsuA | 16S pseudouridylate 516 synthase; Belongs to the pseudouridine synthase RsuA family. (239 aa) | ||||
rplY | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (94 aa) | ||||
glk | Glucokinase; Belongs to the bacterial glucokinase family. (321 aa) | ||||
tktB | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa) | ||||
stpA | DNA-bending protein with chaperone activity; Belongs to the histone-like protein H-NS family. (130 aa) | ||||
yqaB | Putative phosphatase. (188 aa) | ||||
hycI | Protease; Involved in processing C-terminal end of HycE. (145 aa) | ||||
hycF | Hydrogenase 4 Fe-S subunit. (180 aa) | ||||
hycE | Hydrogenase 3, large subunit (part of FHL complex). (569 aa) | ||||
hypB | Guanine-nucleotide binding protein; Functions as nickel donor for large subunit of hydrogenase 3. (290 aa) | ||||
galR | Repressor of galETK operon. (338 aa) | ||||
lysS-2 | lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) | ||||
tktA-2 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa) | ||||
exuR | Negative regulator of exu regulon, exuT, uxaAC, and uxuB. (258 aa) |