node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
clpA | clpP | KPN_00915 | KPN_00399 | ATP-binding component of serine protease; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.989 |
clpA | clpX | KPN_00915 | KPN_00400 | ATP-binding component of serine protease; Belongs to the ClpA/ClpB family. | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.623 |
clpB | clpP | KPN_02915 | KPN_00399 | ATP-dependent protease, Hsp 100; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.956 |
clpB | clpX | KPN_02915 | KPN_00400 | ATP-dependent protease, Hsp 100; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.613 |
clpP | clpA | KPN_00399 | KPN_00915 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-binding component of serine protease; Belongs to the ClpA/ClpB family. | 0.989 |
clpP | clpB | KPN_00399 | KPN_02915 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent protease, Hsp 100; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.956 |
clpP | clpX | KPN_00399 | KPN_00400 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.999 |
clpX | clpA | KPN_00400 | KPN_00915 | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | ATP-binding component of serine protease; Belongs to the ClpA/ClpB family. | 0.623 |
clpX | clpB | KPN_00400 | KPN_02915 | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | ATP-dependent protease, Hsp 100; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.613 |
clpX | clpP | KPN_00400 | KPN_00399 | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.999 |
cytR | pdhR | KPN_04229 | KPN_00117 | Regulator for deo operon, udp, cdd, tsx, nupC, and nupG. | Transcriptional regulator of pyruvate dehydrogenase complex. | 0.402 |
envZ | narL | KPN_03774 | KPN_02217 | Osmolarity sensor protein. | Pleiotrophic regulation of anaerobic respiration; Response regulator for nar, frd, dms and tor genes. | 0.469 |
envZ | ompR | KPN_03774 | KPN_03775 | Osmolarity sensor protein. | Osmolarity response regulator. | 0.998 |
fadR | gcvA | KPN_02311 | KPN_03159 | Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism. | Positive regulator of gcv operon; Belongs to the LysR transcriptional regulatory family. | 0.696 |
fadR | metJ | KPN_02311 | KPN_04232 | Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism. | Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.796 |
fadR | pdhR | KPN_02311 | KPN_00117 | Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism. | Transcriptional regulator of pyruvate dehydrogenase complex. | 0.616 |
gcvA | fadR | KPN_03159 | KPN_02311 | Positive regulator of gcv operon; Belongs to the LysR transcriptional regulatory family. | Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism. | 0.696 |
gcvA | metJ | KPN_03159 | KPN_04232 | Positive regulator of gcv operon; Belongs to the LysR transcriptional regulatory family. | Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.571 |
metJ | fadR | KPN_04232 | KPN_02311 | Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism. | 0.796 |
metJ | gcvA | KPN_04232 | KPN_03159 | Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Positive regulator of gcv operon; Belongs to the LysR transcriptional regulatory family. | 0.571 |