STRINGSTRING
metR metR metJ metJ cytR cytR glpR glpR ompR ompR envZ envZ gcvA gcvA clpB clpB galF galF fadR fadR narL narL clpA clpA clpX clpX clpP clpP pdhR pdhR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metRRegulator for metE and metH; Belongs to the LysR transcriptional regulatory family. (317 aa)
metJTranscriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. (105 aa)
cytRRegulator for deo operon, udp, cdd, tsx, nupC, and nupG. (336 aa)
glpRRepressor of the glp operon. (252 aa)
ompROsmolarity response regulator. (239 aa)
envZOsmolarity sensor protein. (451 aa)
gcvAPositive regulator of gcv operon; Belongs to the LysR transcriptional regulatory family. (305 aa)
clpBATP-dependent protease, Hsp 100; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (857 aa)
galFUDP-glucose pyrophosphorylase. (298 aa)
fadRFatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism. (239 aa)
narLPleiotrophic regulation of anaerobic respiration; Response regulator for nar, frd, dms and tor genes. (216 aa)
clpAATP-binding component of serine protease; Belongs to the ClpA/ClpB family. (759 aa)
clpXATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (424 aa)
clpPATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (194 aa)
pdhRTranscriptional regulator of pyruvate dehydrogenase complex. (259 aa)
Your Current Organism:
Klebsiella pneumoniae MGH78578
NCBI taxonomy Id: 272620
Other names: K. pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae MCG 78578, Klebsiella pneumoniae str. MCG 78578, Klebsiella pneumoniae subsp. pneumoniae ATCC 700721, Klebsiella pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae subsp. pneumoniae str. MGH 78578, Klebsiella pneumoniae subsp. pneumoniae strain MGH 78578
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