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ddl ddl murA murA murF murF murB murB mreB mreB rodA rodA LBA0805 LBA0805 mraY mraY murD murD murG murG ftsQ ftsQ ftsW ftsW LBA1159 LBA1159 LBA1509 LBA1509 murC murC pbpF pbpF vanY vanY murE murE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ddlD-alanine-d-alanine ligase; Cell wall formation. (360 aa)
murAUdp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (431 aa)
murFD-ala-d-ala adding enzyme; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (455 aa)
murBUdp-n-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (298 aa)
mreBCell shape determining protein; MreB. (329 aa)
rodARod shape-determining protein; RodA; Belongs to the SEDS family. (397 aa)
LBA0805Penicillin-binding protein; PBP2B. (720 aa)
mraYp-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (322 aa)
murDUDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (459 aa)
murGp-N-acetylmuramoyl-pentapeptide-transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (368 aa)
ftsQCell division protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. (285 aa)
ftsWCell division protein; FtsW; Belongs to the SEDS family. (394 aa)
LBA1159Penicillin binding protein 1A; Pbp1. (776 aa)
LBA1509Penicillin-binding protein. (702 aa)
murCUDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (437 aa)
pbpFPenicillin-binding protein. (685 aa)
vanYSerine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. (432 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L- lysine ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily. (523 aa)
Your Current Organism:
Lactobacillus acidophilus
NCBI taxonomy Id: 272621
Other names: L. acidophilus NCFM, Lactobacillus acidophilus NCFM, Lactobacillus acidophilus str. NCFM, Lactobacillus acidophilus strain NCFM
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