STRINGSTRING
dsbD-2 dsbD-2 lpg3003 lpg3003 parC parC coxG coxG glmU glmU priA priA bipA bipA rep rep infC infC rplT rplT lphB lphB murE3 murE3 dotB dotB mviN mviN smc smc lpg2619 lpg2619 murF murF mraY mraY murD murD ftsW ftsW murC murC murB murB ddlA ddlA ftsQ ftsQ ftsZ ftsZ topA topA pcgL pcgL lpg2582 lpg2582 rlpA-2 rlpA-2 mltA mltA lpg2493 lpg2493 lepB lepB ddpX ddpX deaD deaD prfA prfA murI murI secB secB hepA hepA lpg2192 lpg2192 pksJ pksJ lpg2077 lpg2077 lpg2046 lpg2046 cpoB cpoB recG recG pilT pilT lpg1996 lpg1996 lpg1994 lpg1994 lpg1986 lpg1986 lpg1887 lpg1887 legC2 legC2 hupB hupB vacJ vacJ uvrD uvrD mrp mrp lpg1812 lpg1812 fliO fliO fliP fliP fliQ fliQ fliR fliR flhA flhA lpg1784 lpg1784 prfB prfB lpg1764 lpg1764 fliH fliH fliJ fliJ mpl mpl iscS iscS lpg1745 lpg1745 ydiC ydiC minD minD frr frr lpg1688 lpg1688 ruvB ruvB minC minC bamB bamB lpg1509 lpg1509 rlpA rlpA zapD zapD gyrA gyrA pilZ pilZ mltG mltG erpA erpA rsfS rsfS pbpA pbpA rodA rodA lptE lptE fliS fliS ruvA ruvA traA traA flgK flgK lpg1224 lpg1224 flgD flgD lpg1191 lpg1191 bamD bamD murJ murJ lpg0965 lpg0965 mfd mfd era era pilP pilP pilO pilO pilN pilN pilM pilM murE murE pbpB pbpB lpg0908 lpg0908 lpg0907 lpg0907 lpg0906 lpg0906 lpg0885 lpg0885 prfC prfC recQ recQ cycH cycH lpg0863 lpg0863 ccmF ccmF ccmE ccmE lpg0859 lpg0859 ccmC ccmC ccmB ccmB ccmA ccmA murA murA yrbA yrbA lpg0844 lpg0844 lpg0841 lpg0841 lpg0838 lpg0838 lpg0837 lpg0837 murG murG lpg0762 lpg0762 dnaB dnaB lpg0735 lpg0735 parE parE lpg0689 lpg0689 dsbD dsbD lpg0631 lpg0631 lpg0630 lpg0630 lpg0629 lpg0629 pilE3 pilE3 lpg0606 lpg0606 lpg0605 lpg0605 lpg0603 lpg0603 lpg0602 lpg0602 ycf24 ycf24 comM comM lpg0507 lpg0507 bamA bamA uppS uppS argR argR lpg0385 lpg0385 smpA smpA surA surA ostA ostA lpg0296 lpg0296 lpg0275 lpg0275 lpg0269 lpg0269 lpg0250 lpg0250 lpg0167 lpg0167 lpg0134 lpg0134 engB engB lpg0095 lpg0095 lpg0075 lpg0075 gyrB gyrB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dsbD-2Thiol:disulfide interchange protein DsbD. (459 aa)
lpg3003Conserved hypothetical protein TIGR00278; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (81 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (751 aa)
coxGCytochrome c oxidase, assembly transmembrane protein CoxG. (181 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (461 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (725 aa)
bipAVirulence regulator BipA. (608 aa)
repATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (665 aa)
infCTranslational initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (129 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (119 aa)
lphBLphB. (543 aa)
murE3UDP-N-acetylmuramyl tripeptide synthase. (342 aa)
dotBDotB. (387 aa)
mviNIntegral membrane protein (putative virulence factor) MviN, possible role in motility; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (523 aa)
smcChromosome segregation SMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1164 aa)
lpg2619Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family. (259 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (461 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (372 aa)
murDUDP-N-muramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (447 aa)
ftsWCell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (394 aa)
murCUDP-N-acetylmuramate:L-alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. (469 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (312 aa)
ddlAD-alanine-D-alanine ligase A; Cell wall formation. (368 aa)
ftsQCell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (239 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (398 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (759 aa)
pcgLD-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (243 aa)
lpg2582Hypothetical protein. (388 aa)
rlpA-2Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (160 aa)
mltAMembrane-bound lytic murein transglycosylase A. (457 aa)
lpg2493Small heat shock protein HspC2; Belongs to the small heat shock protein (HSP20) family. (164 aa)
lepBLepB. (1294 aa)
ddpXD-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (241 aa)
deaDATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (589 aa)
prfAPeptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (362 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (288 aa)
secBProtein export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (162 aa)
hepAATP-dependent RNA helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (958 aa)
lpg2192Small HspC2 heat shock protein; Belongs to the small heat shock protein (HSP20) family. (188 aa)
pksJPolyketide synthase, type I. (3780 aa)
lpg2077TraI. (1981 aa)
lpg2046ABC transporter, ATP binding protein. (245 aa)
cpoBOuter membrane protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (322 aa)
recGATP dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (690 aa)
pilTTwitching motility protein PilT. (344 aa)
lpg1996Hypothetical protein. (268 aa)
lpg1994(outer) membrane bound lytic murein transglycosylase family protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (397 aa)
lpg1986Hypothetical protein. (950 aa)
lpg1887Hypothetical protein. (117 aa)
legC2Microtubule binding protein, putative; Conserved gene; coiled-coil-containing protein. (405 aa)
hupBHupB DNA binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (100 aa)
vacJLipoprotein VacJ-like. (260 aa)
uvrDDNA dependent ATPase I and helicase II. (730 aa)
mrpATPase (Mrp); Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (357 aa)
lpg1812ATP-dependent DNA helicase (UvrD/Rep helicase); Belongs to the helicase family. UvrD subfamily. (1076 aa)
fliOFlagellar assembly protein FliO. (136 aa)
fliPFlagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (249 aa)
fliQFlagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
fliRFlagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (256 aa)
flhAFlagellar biosynthetic protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (692 aa)
lpg1784Flagellar GTP-binding protein FlhF. (386 aa)
prfBPeptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (335 aa)
lpg1764ATPase associated with chromosome architecture. (434 aa)
fliHFlagellar assembly protein FliH. (212 aa)
fliJFlagellar protein FliJ. (151 aa)
mplUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (455 aa)
iscSCysteine desulfurase NifS. (387 aa)
lpg1745NifU family iron binding protein, [Fe-S] cluster formation/repair protein IscU, HesB. (127 aa)
ydiCHesB family protein; Belongs to the HesB/IscA family. (122 aa)
minDSeptum site-determining protein MinD. (276 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
lpg1688Possible flagellar hook-length control protein. (414 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (343 aa)
minCSeptum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (236 aa)
bamBPQQ (pyrrolo quinoline) WD40-like repeat, enzyme repeat domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (387 aa)
lpg1509D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (430 aa)
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (273 aa)
zapDHypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (248 aa)
gyrADNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (871 aa)
pilZType 4 fimbrial biogenesis protein PilZ. (113 aa)
mltGPeriplasmic solute-binding protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (332 aa)
erpAHypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. (130 aa)
rsfSHypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (112 aa)
pbpAPenicillin binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (626 aa)
rodARod shape determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (372 aa)
lptERare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (163 aa)
fliSFlagellar protein FliS. (136 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (199 aa)
traAConjugal transfer protein TraA. (889 aa)
flgKFlagellar hook associated protein 1 FlgK; Belongs to the flagella basal body rod proteins family. (649 aa)
lpg1224Muramidase, peptidoglycan hydrolase FlgJ. (294 aa)
flgDFlagellar basal body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein. (225 aa)
lpg1191Glycosyl hydrolase family 3. (395 aa)
bamDCompetence lipoprotein ComL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (260 aa)
murJVirulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (535 aa)
lpg0965LphB. (515 aa)
mfdTranscription repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1153 aa)
eraGTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (311 aa)
pilPType IV pilus biogenesis protein PilP. (195 aa)
pilOType IV pilus biogenesis protein PilO. (211 aa)
pilNType IV pilus biogenesis protein PilN. (182 aa)
pilMType IV pilus biogenesis protein PilM. (354 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase MurE; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (483 aa)
pbpBPenicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (553 aa)
lpg0908Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (233 aa)
lpg0907Negative regulator of flagellin synthesis. (106 aa)
lpg0906Flagellar biosynthesis/type III secretory pathway chaperone. (165 aa)
lpg0885Glycosyl hydrolase. (358 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (526 aa)
recQATP-dependent DNA helicase RecQ. (608 aa)
cycHCytochrome c type biogenesis protein CcmH. (243 aa)
lpg0863C-type cytochrome biogenesis protein CcmH; Possible subunit of a heme lyase. (133 aa)
ccmFCytochrome c-type biogenesis protein CcmF. (650 aa)
ccmECytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (143 aa)
lpg0859Cytochrome c-type biogenesis protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (43 aa)
ccmCHeme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (263 aa)
ccmBHeme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (226 aa)
ccmAHeme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (246 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (422 aa)
yrbAHypothetical BolA like protein; Belongs to the BolA/IbaG family. (81 aa)
lpg0844Signal peptide protein, toluene tolerance protein Ttg2D. (202 aa)
lpg0841Toluene tolerance ABC transporter, ATP binding protein Ttg2A. (265 aa)
lpg0838Hypothetical protein. (189 aa)
lpg0837Hypothetical protein. (169 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (363 aa)
lpg0762O-antigen initiating glycosyl transferase group 4-UDP-N-acetylmuramyl pentapeptide phosphotransferase/(N-acetylgalactosaminyl transferase TrsF). (334 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (460 aa)
lpg0735DNA helicase, SNF2/RAD54 family domain protein. (1088 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (626 aa)
lpg0689DNA binding stress protein; Belongs to the Dps family. (146 aa)
dsbDThiol:disulfide interchange protein DsbD. (596 aa)
lpg0631Type IV fimbrial biogenesis protein PilV. (179 aa)
lpg0630Type IV fimbrial biogenesis PilW related protein, transmembrane). (355 aa)
lpg0629Tfp pilus assembly protein PilX. (170 aa)
pilE3Type IV pilin. (149 aa)
lpg0606Metal-sulfur cluster biosynthetic enzyme. (123 aa)
lpg0605Nitrogen fixation protein (Fe-S cluster formation) NifU. (149 aa)
lpg0603ABC transporter, permease component. (428 aa)
lpg0602ATP transporter, ABC binding component, ATP-binding protein. (250 aa)
ycf24ABC transporter, permease. (482 aa)
comMCompetence related protein ComM. (503 aa)
lpg0507Outer membrane protein OmpH; Belongs to the skp family. (166 aa)
bamAOuter membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (786 aa)
uppSUndecaprenyl diphosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (238 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (104 aa)
lpg0385LemA protein. (193 aa)
smpASmall protein A, tmRNA-binding. (114 aa)
surAPeptidyl-prolyl cis-trans isomerase D (SurA); Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (446 aa)
ostAOrganic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (889 aa)
lpg0296Hypothetical phosphotransferase. (348 aa)
lpg0275SdbA. (1116 aa)
lpg0269Hypothetical protein. (520 aa)
lpg0250ATP-dependent RNA helicase, DEAD box family; Belongs to the DEAD box helicase family. (414 aa)
lpg0167Peptide chain release factor. (136 aa)
lpg0134Hypothetical protein. (356 aa)
engBGTP binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (200 aa)
lpg0095Cytosolic IMP-GMP specific 5'-nucleotidase. (459 aa)
lpg0075Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (104 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (806 aa)
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
Server load: low (20%) [HD]