Your Input: | |||||
lpg2156 | Sid related protein-like; SdeC, SdeB, SdeA, SidE, AliA-like. (1926 aa) | ||||
lpg2153 | Sid related protein-like; SdeC, SdeB, AliA, SdeA, SdeD-like. (1533 aa) | ||||
sdeA | Sid related protein-like; Secreted effector that interferes with the host cell ubiquitin pathway and is required for intracellular bacterial replication. Catalyzes the ubiquitination of several mammalian Rab proteins (Rab33b, Rab1, Rab6a and Rab30) during L.pneumophila infection, without engaging the standard cellular enzyme cascade (E1 and E2). Transfers an ADP-ribose moiety from NAD to the 'Arg-42' residue of ubiquitin in a reaction that releases nicotinamide. The modified ubiquitin is subsequently transferred to serine residues of the substrate protein via a phosphoribose linker tha [...] (1506 aa) |