STRINGSTRING
lvrC lvrC lpg0124 lpg0124 np20 np20 lpg0467 lpg0467 fis fis lpg0746 lpg0746 csrA-2 csrA-2 fleQ fleQ fis-2 fis-2 lpg1727 lpg1727 fis-3 fis-3 lpg1903 lpg1903 lpg1912 lpg1912 csrA csrA hpd hpd rpoD rpoD feoA feoA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lvrCLvrC; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (67 aa)
lpg0124Cytochrome c4. (200 aa)
np20Transcriptional regulator np20, Fur family; Belongs to the Fur family. (177 aa)
lpg0467Zinc metalloprotease; Extracellular zinc metalloprotease. (543 aa)
fisDNA binding protein Fis; Belongs to the transcriptional regulatory Fis family. (93 aa)
lpg0746IraAB. (502 aa)
csrA-2Global regulator (carbon storage regulator); A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (82 aa)
fleQTranscriptional regulator FleQ. (471 aa)
fis-2Hypothetical protein; Transcription factors / DNA binding proteins, Replication and Repair; Belongs to the transcriptional regulatory Fis family. (98 aa)
lpg1727Hydrolase. (261 aa)
fis-3Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family. (95 aa)
lpg1903Hydrolase. (300 aa)
lpg1912Sensory box histidine kinase/response regulator. (910 aa)
csrACarbon storage regulator RsmA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (78 aa)
hpd4-hydroxyphenylpyruvate dioxygenase; Catalyzes the transformation of p-hydroxyphenylpyruvate into HGA. Has hemolytic and brown pigment production activity. (361 aa)
rpoDRNA polymerase sigma 70 factor (RpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (623 aa)
feoAFerrous iron transporter A. (75 aa)
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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