STRINGSTRING
lpg1791 lpg1791 fliM fliM legC2 legC2 lpg1887 lpg1887 lpg2153 lpg2153 lpg2156 lpg2156 sdeA sdeA motA-2 motA-2 motB-2 motB-2 lepB lepB lpg2535 lpg2535 smc smc lpg0098 lpg0098 fliG fliG motB motB motA motA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lpg1791Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family. (109 aa)
fliMFlagellar protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. (355 aa)
legC2Microtubule binding protein, putative; Conserved gene; coiled-coil-containing protein. (405 aa)
lpg1887Hypothetical protein. (117 aa)
lpg2153Sid related protein-like; SdeC, SdeB, AliA, SdeA, SdeD-like. (1533 aa)
lpg2156Sid related protein-like; SdeC, SdeB, SdeA, SidE, AliA-like. (1926 aa)
sdeASid related protein-like; Secreted effector that interferes with the host cell ubiquitin pathway and is required for intracellular bacterial replication. Catalyzes the ubiquitination of several mammalian Rab proteins (Rab33b, Rab1, Rab6a and Rab30) during L.pneumophila infection, without engaging the standard cellular enzyme cascade (E1 and E2). Transfers an ADP-ribose moiety from NAD to the 'Arg-42' residue of ubiquitin in a reaction that releases nicotinamide. The modified ubiquitin is subsequently transferred to serine residues of the substrate protein via a phosphoribose linker tha [...] (1506 aa)
motA-2Chemotaxis (motility protein A) transmembrane. (301 aa)
motB-2Chemotaxis (motility protein B) transmembrane. (312 aa)
lepBLepB. (1294 aa)
lpg2535Myoglobin-like. (135 aa)
smcChromosome segregation SMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1164 aa)
lpg0098Two component sensor and regulator, histidine kinase response regulator. (150 aa)
fliGFlagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. (329 aa)
motBFlagellar motor protein MotB. (273 aa)
motAFlagellar motor protein MotA. (257 aa)
Your Current Organism:
Legionella pneumophila Philadelphia
NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila str. Philadelphia-1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1
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