(25 nodes) Mixed, incl. Terpenoid backbone biosynthesis, and Cytochrome-c oxidase activity network (Listeria innocua)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	lin0010	Lin0010 protein; Similar to mevalonate kinase. (322 aa)
	lin0011	Lin0011 protein; Similar to mevalonate diphosphate decarboxylase. (339 aa)
	lin0012	Lin0012 protein; Similar to mevalonate kinases. (360 aa)
	qoxA	AA3-600 quinol oxidase subunit II; Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I. (368 aa)
	qoxB	AA3-600 quinol oxidase subunit I; Belongs to the heme-copper respiratory oxidase family. (659 aa)
	qoxC	AA3-600 quinol oxidase subunit III. (203 aa)
	qoxD	QoxD protein; Highly similar to quinol oxidase aa3-600 chain IV. (110 aa)
	lin0147	Lin0147 protein. (116 aa)
	lin0387	Uncharacterized Nudix hydrolase lin0387; Similar to different proteins. (169 aa)
	lin0459	Lin0459 protein. (281 aa)
	lin0821	Similar to 3-hydroxy-3-methylglutaryl-coenzyme a reductase; Belongs to the HMG-CoA reductase family. (426 aa)
	lin1420	Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (358 aa)
	tcsA	CD4+ T cell-stimulating antigen, lipoprotein. (357 aa)
	lin1426	Lin1426 protein; Similar to sugar ABC transporter, ATP-binding protein. (513 aa)
	lin1427	Lin1427 protein; Similar to ABC transporter (permease proteins); Belongs to the binding-protein-dependent transport system permease family. (350 aa)
	lin1428	Lin1428 protein; Similar to sugar ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. (316 aa)
	lin1429	Lin1429 protein; Similar to putative proteases. (430 aa)
	lin1430	Lin1430 protein; Similar to putative protease. (428 aa)
	lin1453	Lin1453 protein; Similar to Acetyl-CoA:acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
	lin1454	Lin1454 protein; Similar to hydroxy-3-methylglutaryl coenzyme A synthase. (388 aa)
	lin1817	Lin1817 protein; Similar to deoxyguanosine kinase/deoxyadenosine kinase(I) subunit. (214 aa)
	ctaB	Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. (301 aa)
	ctaA	Heme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily. (305 aa)
	lin2194	Lin2194 protein; Similar to lipases. (347 aa)
	lin2490	Conserved hypothetical protein similar to B. subtilis YhfK protein. (209 aa)

Your Current Organism:

Listeria innocua

NCBI taxonomy Id: 272626
Other names: L. innocua Clip11262, Listeria innocua Clip11262, Listeria innocua str. Clip11262, Listeria innocua strain Clip11262

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ctaA	ctaB	gene:17566522	gene:17566521	Heme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily.	Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.	0.996
ctaA	qoxA	gene:17566522	gene:17564324	Heme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily.	AA3-600 quinol oxidase subunit II; Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.	0.731
ctaA	qoxB	gene:17566522	gene:17564325	Heme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily.	AA3-600 quinol oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.	0.745
ctaA	qoxC	gene:17566522	gene:17564326	Heme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily.	AA3-600 quinol oxidase subunit III.	0.716
ctaA	qoxD	gene:17566522	gene:17564327	Heme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily.	QoxD protein; Highly similar to quinol oxidase aa3-600 chain IV.	0.423
ctaB	ctaA	gene:17566521	gene:17566522	Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.	Heme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily.	0.996
ctaB	qoxA	gene:17566521	gene:17564324	Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.	AA3-600 quinol oxidase subunit II; Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.	0.996
ctaB	qoxB	gene:17566521	gene:17564325	Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.	AA3-600 quinol oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.	0.998
ctaB	qoxC	gene:17566521	gene:17564326	Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.	AA3-600 quinol oxidase subunit III.	0.998
ctaB	qoxD	gene:17566521	gene:17564327	Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.	QoxD protein; Highly similar to quinol oxidase aa3-600 chain IV.	0.992
lin0010	lin0011	gene:17564321	gene:17564322	Lin0010 protein; Similar to mevalonate kinase.	Lin0011 protein; Similar to mevalonate diphosphate decarboxylase.	0.989
lin0010	lin0012	gene:17564321	gene:17564323	Lin0010 protein; Similar to mevalonate kinase.	Lin0012 protein; Similar to mevalonate kinases.	0.998
lin0010	lin0821	gene:17564321	gene:17565148	Lin0010 protein; Similar to mevalonate kinase.	Similar to 3-hydroxy-3-methylglutaryl-coenzyme a reductase; Belongs to the HMG-CoA reductase family.	0.997
lin0010	lin1420	gene:17564321	gene:17565751	Lin0010 protein; Similar to mevalonate kinase.	Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).	0.845
lin0010	lin1454	gene:17564321	gene:17565785	Lin0010 protein; Similar to mevalonate kinase.	Lin1454 protein; Similar to hydroxy-3-methylglutaryl coenzyme A synthase.	0.855
lin0010	qoxB	gene:17564321	gene:17564325	Lin0010 protein; Similar to mevalonate kinase.	AA3-600 quinol oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.	0.406
lin0011	lin0010	gene:17564322	gene:17564321	Lin0011 protein; Similar to mevalonate diphosphate decarboxylase.	Lin0010 protein; Similar to mevalonate kinase.	0.989
lin0011	lin0012	gene:17564322	gene:17564323	Lin0011 protein; Similar to mevalonate diphosphate decarboxylase.	Lin0012 protein; Similar to mevalonate kinases.	0.998
lin0011	lin0387	gene:17564322	gene:17564714	Lin0011 protein; Similar to mevalonate diphosphate decarboxylase.	Uncharacterized Nudix hydrolase lin0387; Similar to different proteins.	0.716
lin0011	lin0821	gene:17564322	gene:17565148	Lin0011 protein; Similar to mevalonate diphosphate decarboxylase.	Similar to 3-hydroxy-3-methylglutaryl-coenzyme a reductase; Belongs to the HMG-CoA reductase family.	0.872