STRINGSTRING
lin1775 lin1775 lin1675 lin1675 citC citC lin1569 lin1569 lin1354 lin1354 pduQ pduQ lin1130 lin1130 guaB guaB lin2956 lin2956 lin1072 lin1072 lin1049 lin1049 lin0821 lin0821 hisD hisD lin0563 lin0563 lin0540 lin0540 lin2152 lin2152 lin2338 lin2338 lin0493 lin0493 lin0526 lin0526 lin0070 lin0070 lin0179 lin0179 ldh ldh lin0362 lin0362 lin2717 lin2717 hom hom lin2454 lin2454 lin1525 lin1525 lin1459 lin1459 lin1413 lin1413 leuB leuB ilvC ilvC lin2085 lin2085 gpsA gpsA lin2029 lin2029 fabG fabG lin1848 lin1848 lin1792 lin1792
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lin1775Lin1775 protein; Similar to L-lactate dehydrogenases; Belongs to the LDH/MDH superfamily. (302 aa)
lin1675Similar to Alcohol-acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (866 aa)
citCIsocitrate dehydrogenase [NADP]; Highly similar to isocitrate dehyrogenases. (420 aa)
lin1569L-lactate dehydrogenase 2; Catalyzes the conversion of lactate to pyruvate. (311 aa)
lin13541-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (380 aa)
pduQPduQ protein; Similar to NADPH-dependent butanol dehydrogenase. (379 aa)
lin1130Lin1130 protein; Similar to NADPH-dependent butanol dehydrogenase. (372 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa)
lin2956Lin2956 protein; Similar to D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (395 aa)
lin1072Ribulose-5-phosphate reductase; Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate; Belongs to the zinc-containing alcohol dehydrogenase family. (341 aa)
lin1049Lin1049 protein; Similar to L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (316 aa)
lin0821Similar to 3-hydroxy-3-methylglutaryl-coenzyme a reductase; Belongs to the HMG-CoA reductase family. (426 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
lin0563Lin0563 protein; Similar to NADH-dependent butanol dehydrogenase. (393 aa)
lin0540Lin0540 protein; Similar to 6-phospho-beta-glucosidase. (440 aa)
lin21522-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (301 aa)
lin2338Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (289 aa)
lin0493Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (291 aa)
lin0526Lin0526 protein; Similar to 6-phospho-beta-glucosidase. (438 aa)
lin0070Lin0070 protein; Similar to phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
lin0179Lin0179 protein; Similar to inosine monophosphate dehydrogenase. (502 aa)
ldhL-lactate dehydrogenase 1; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (313 aa)
lin0362NAD-dependent glycerol dehydrogenase; Involved in the glycerol metabolism. Catalyzes the NAD- dependent oxidation of glycerol to dihydroxyacetone (glycerone). GolD specifically uses NAD; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (254 aa)
lin2717Lin2717 protein; Similar to Chain A, Dihydrofolate Reductase. (174 aa)
homHighly similar to homoserine dehydrogenase. (428 aa)
lin2454Lin2454 protein; Similar to 6-phospho-beta-glucosidase. (435 aa)
lin1525Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa)
lin1459UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (298 aa)
lin14136-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (472 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (350 aa)
ilvCKetol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa)
lin2085Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa)
gpsASimilar to NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (338 aa)
lin2029Lin2029 protein; Similar to malolactic enzyme (malate dehydrogenase). (547 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
lin1848Lin1848 protein; Similar to glycerol dehydrogenase. (368 aa)
lin1792Lin1792 protein; Similar to glycerate dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa)
Your Current Organism:
Listeria innocua
NCBI taxonomy Id: 272626
Other names: L. innocua Clip11262, Listeria innocua Clip11262, Listeria innocua str. Clip11262, Listeria innocua strain Clip11262
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