STRINGSTRING
lin2459 lin2459 lin2472 lin2472 lin2515 lin2515 lin2616 lin2616 lin2626 lin2626 phoR phoR thrB thrB lin2702 lin2702 lin2727 lin2727 lin2799 lin2799 lin2801 lin2801 lin2815 lin2815 lin2817 lin2817 lin2827 lin2827 lin2831 lin2831 lin2832 lin2832 lin2843 lin2843 lin2844 lin2844 lin2845 lin2845 lin2860 lin2860 lin2856 lin2856 lin2931 lin2931 lin2907 lin2907 lin2906 lin2906 lin2905 lin2905 lin2981 lin2981 lin2965 lin2965 lin0768 lin0768 lin0776 lin0776 lin0777 lin0777 lin0871 lin0871 lin0873 lin0873 lin0874 lin0874 rsbW rsbW lin0900 lin0900 lin0914 lin0914 lin0923 lin0923 lin0967 lin0967 lin1020 lin1020 lin1080 lin1080 lin1111 lin1111 lin1223 lin1223 ribC ribC lin1376 lin1376 lisK lisK lin1494 lin1494 udk udk lin1543 lin1543 lin1573 lin1573 lin1598 lin1598 cheA cheA lin0627 lin0627 lin0599 lin0599 lin0547 lin0547 lin0546 lin0546 lin0543 lin0543 lin0507 lin0507 lin0501 lin0501 lin0448 lin0448 lin0446 lin0446 lin0445 lin0445 lin0425 lin0425 lin0423 lin0423 lin0422 lin0422 lin0421 lin0421 lin0403 lin0403 lin0393 lin0393 lin0392 lin0392 lin0377 lin0377 lin0376 lin0376 lin0369 lin0369 lin0366 lin0366 lin0365 lin0365 lin0341 lin0341 lin0327 lin0327 lin0326 lin0326 lin0325 lin0325 lin0316 lin0316 lin0263 lin0263 lin0253 lin0253 lin0229 lin0229 lin0143 lin0143 lin0033 lin0033 lin0026 lin0026 lin0021 lin0021 lin0010 lin0010 pykA pykA lin1606 lin1606 lin1628 lin1628 lin1831 lin1831 lin1852 lin1852 lin1861 lin1861 lin1865 lin1865 lin1928 lin1928 lin1934 lin1934 lin1980 lin1980 resE resE lin2105 lin2105 lin2110 lin2110 lin2119 lin2119 lin2199 lin2199 lin2201 lin2201 lin2203 lin2203 lin2240 lin2240 lin2241 lin2241 lin2242 lin2242 lin2243 lin2243 lin2249 lin2249 lin2277 lin2277 fruA fruA fruB fruB lin2435 lin2435 lin2458 lin2458
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lin2459Permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (433 aa)
lin2472Lin2472 protein; Similar to phosphotransferase system (PTS) beta-glucoside-specific enzyme IIB component. (104 aa)
lin2515Lin2515 protein; Similar to two-component sensor histidine kinase. (380 aa)
lin2616Gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (322 aa)
lin2626HPr-P(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable c [...] (312 aa)
phoRTwo-component sensor histidine kinase. (591 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (288 aa)
lin2702Lin2702 protein. (306 aa)
lin2727Lin2727 protein; Similar to two-component sensor histidine kinase. (459 aa)
lin2799Lin2799 protein; Similar to hypothetical PTS enzyme IIB component. (90 aa)
lin2801Lin2801 protein; Similar to transcriptional antiterminator. (688 aa)
lin2815Lin2815 protein; Similar to PTS system galactitol-specific enzyme IIB component. (93 aa)
lin2817Lin2817 protein; Similar to transcriptional antiterminator (BglG family). (689 aa)
lin2827Lin2827 protein; Similar to the two components sensor protein kdpD. (896 aa)
lin2831Lin2831 protein; Similar to cellobiose phosphotransferase enzyme IIB component. (101 aa)
lin2832Permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (435 aa)
lin2843PTS-dependent dihydroxyacetone kinase 1, dihydroxyacetone-binding subunit DhaK; Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP. (329 aa)
lin2844PEP-dependent dihydroxyacetone kinase 1, ADP-binding subunit DhaL; ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaL-ADP is converted to DhaL-ATP via a phosphoryl group transfer from DhaM and transmits it to dihydroxyacetone binds to DhaK. (198 aa)
lin2845PEP-dependent dihydroxyacetone kinase 1, phosphoryl donor subunit DhaM; Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone. Belongs to the PEP-utilizing enzyme family. (124 aa)
lin2860Lin2860 protein; Highly similar to gluconate kinase; Belongs to the FGGY kinase family. (504 aa)
lin2856Permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (454 aa)
lin2931Lin2931 protein; Similar to phosphotransferase system mannitol-specific enzyme IIBC. (468 aa)
lin2907Beta-glucoside kinase; Catalyzes the ATP-dependent phosphorylation of cellobiose to produce cellobiose-6'-P. May have a dual role of kinase and transcriptional regulator of the cellobiose-PTS operon. Belongs to the ROK (NagC/XylR) family. (294 aa)
lin2906Permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (450 aa)
lin2905Lin2905 protein; Similar to PTS cellobiose-specific enzyme IIB. (100 aa)
lin2981Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family. (483 aa)
lin2965Similar to unknown proteins; Belongs to the glycerate kinase type-1 family. (373 aa)
lin0768Lin0768 protein. (309 aa)
lin0776Lin0776 protein; Similar to mannose-specific phosphotransferase system (PTS) component IIB. (161 aa)
lin0777Lin0777 protein; Similar to mannose-specific phosphotransferase system (PTS) component IIA. (144 aa)
lin0871Lin0871 protein; Similar to transcriptional regulator (antiterminator). (672 aa)
lin0873Lin0873 protein; Similar to PTS system, beta-glucoside enzyme IIB component. (111 aa)
lin0874Permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (441 aa)
rsbWsigma-B activity negative regulator RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). (157 aa)
lin0900Permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (428 aa)
lin0914Lin0914 protein; Similar to PTS system, IIB component. (101 aa)
lin0923Similar to pantothenate kinase. (306 aa)
lin0967NAD kinase 1; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (264 aa)
lin1020Similar to two-component sensor histidine kinase in particular B. subtilis YvqE protein. (352 aa)
lin1080Lin1080 protein; Similar to PTS system, cellobiose-specific IIB component (cel A). (134 aa)
lin1111Lin1111 protein; Similar to bifunctional cobalamin biosynthesis protein CopB, (cobinamide kinase; cobinamide phosphatase guanylyltransferase). (185 aa)
lin1223Lin1223 protein; Similar to PTS system trehalose specific enzyme IIBC. (494 aa)
ribCRiboflavin biosynthesis protein; Highly similar to riboflavin kinase and FAD synthase; Belongs to the ribF family. (314 aa)
lin1376Lin1376 protein; Similar to glucose kinase. (322 aa)
lisKTwo-component sensor histidine kinase. (483 aa)
lin1494Putative pyruvate, phosphate dikinase regulatory protein 1; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (274 aa)
udkSimilar to Uridine kinase. (209 aa)
lin1543Lin1543 protein; Similar to two-component sensor histidine kinase. (479 aa)
lin1573Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (497 aa)
lin1598Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (200 aa)
cheATwo-component sensor histidine kinase CheA; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity). (618 aa)
lin0627Similar to protein kinase. (383 aa)
lin0599Lin0599 protein; Similar to a fusion of two types of conserved hypothetical proteinconserved hypothetical. (589 aa)
lin0547Lin0547 protein; Similar to PTS system, glucitol/sorbitol-specific enzyme IIBC component. (328 aa)
lin0546Lin0546 protein; Similar to PTS system, glucitol/sorbitol-specific enzyme IIA component. (116 aa)
lin0543Similar to tagatose-1,6-diphosphate aldolase; Belongs to the aldolase LacD family. (338 aa)
lin0507Lin0507 protein; Similar to PTS system, Galactitol-specific IIB component. (97 aa)
lin0501Lin0501 protein; Similar to transcription antiterminator BglG family. (686 aa)
lin0448Lin0448 protein; Similar to PTS fructose-specific enzyme IIC component. (368 aa)
lin0446Lin0446 protein; Similar to PTS fructose-specific enzyme IIA component. (154 aa)
lin0445Lin0445 protein; Similar to transcription antiterminator BglG family. (647 aa)
lin0425Lin0425 protein; Similar to transcriptional antiterminator (BglG family). (644 aa)
lin0423Lin0423 protein; Similar to fructose-specific phosphotransferase enzyme IIC. (370 aa)
lin0422Lin0422 protein; Similar to fructose-specific phosphotransferase enzyme IIB. (110 aa)
lin0421Lin0421 protein; Similar to phosphotransferase system enzyme IIA. (152 aa)
lin04035-dehydro-2-deoxygluconokinase; Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2- deoxy-D-gluconate (DKGP). (325 aa)
lin0393Lin0393 protein; Similar to PTS betaglucoside-specific enzyme IIB component. (100 aa)
lin0392Permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (444 aa)
lin0377Lin0377 protein; Similar to PTS system, fructose-specific enzyme IIBC component. (464 aa)
lin0376Lin0376 protein; Similar to PTS system, enzyme IIA component. (148 aa)
lin0369PEP-dependent dihydroxyacetone kinase 2, phosphoryl donor subunit DhaM; Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone. (125 aa)
lin0366PTS-dependent dihydroxyacetone kinase 2, dihydroxyacetone-binding subunit DhaK; Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP. (331 aa)
lin0365PEP-dependent dihydroxyacetone kinase 2, ADP-binding subunit DhaL; ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaL-ADP is converted to DhaL-ATP via a phosphoryl group transfer from DhaM and transmits it to dihydroxyacetone binds to DhaK. (216 aa)
lin0341Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (269 aa)
lin0327Lin0327 protein; Similar to PTS beta-glucoside-specific enzyme IIB component. (96 aa)
lin0326Permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (437 aa)
lin0325Lin0325 protein; Similar to transcriptional antiterminator (BglG family). (623 aa)
lin0316Lin0316 protein; Similar to two-component sensor histidine kinase. (610 aa)
lin0263Protein-arginine kinase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family. (340 aa)
lin0253Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (259 aa)
lin02294-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (291 aa)
lin0143Lin0143 protein; Similar to PTS system mannose-specific, factor IIAB. (321 aa)
lin0033Permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (452 aa)
lin0026Lin0026 protein; Similar to PTS system, beta-glucosides specific enzyme IIABC. (633 aa)
lin0021Lin0021 protein; Similar to PTS system, fructose-specific IIB component. (162 aa)
lin0010Lin0010 protein; Similar to mevalonate kinase. (322 aa)
pykAHighly similar to pyruvate kinases. (585 aa)
lin1606ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
lin1628NAD kinase 2; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (267 aa)
lin1831Lin1831 protein; Similar to phosphotransferase system (PTS) lichenan-specific enzyme IIB component. (102 aa)
lin1852Lin1852 protein; Similar to two-component sensor histidine kinase. (346 aa)
lin1861Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (157 aa)
lin1865Lin1865 protein. (310 aa)
lin1928Similar to unknown proteins. (552 aa)
lin1934Lin1934 protein; Similar to putative serine/threonine-specific protein kinase. (657 aa)
lin1980Putative pyruvate, phosphate dikinase regulatory protein 2; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (270 aa)
resEResE protein; Similar to two-component sensor histidine kinase (ResE). (596 aa)
lin2105Lin2105 protein; Similar to PTS mannose-specific enzyme IIA component. (138 aa)
lin2110Lin2110 protein; Similar to PTS mannose-specific enzyme IIB component. (155 aa)
lin2119Histidine kinase; Similar to two-component sensor histidine kinase. (577 aa)
lin2199Similar to 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (310 aa)
lin2201Lin2201 protein; Similar to PTS system galactitol-specific enzyme IIB component. (91 aa)
lin2203Lin2203 protein; Similar to transcription antiterminator. (668 aa)
lin2240Lin2240 protein; Similar to PTS system, fructose-specific enzyme IIC component. (363 aa)
lin2241Lin2241 protein; Similar to PTS system, fructose-specific enzyme IIB component. (103 aa)
lin2242Lin2242 protein; Similar to PTS system, fructose-specific enzyme IIA component. (157 aa)
lin2243Lin2243 protein; Similar to transcription regulator. (485 aa)
lin2249Lin2249 protein. (338 aa)
lin2277Similar to unknown proteins. (357 aa)
fruAFruA protein; Highly similar to phosphotransferase system (PTS) fructose-specific enzyme IIABC component. (632 aa)
fruBFructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (307 aa)
lin2435Lin2435 protein; Similar to carbohydrate kinases. (372 aa)
lin2458Lin2458 protein; Similar to PTS system, cellobiose-specific enzyme IIB component. (118 aa)
Your Current Organism:
Listeria innocua
NCBI taxonomy Id: 272626
Other names: L. innocua Clip11262, Listeria innocua Clip11262, Listeria innocua str. Clip11262, Listeria innocua strain Clip11262
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