STRINGSTRING
pks3 pks3 mas mas ML0135 ML0135 ML2357 ML2357 ML2355 ML2355 ML2354 ML2354
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
pks3Mycocerosic acid synthase (polyketide synthase); Identical to many polyketide synthases involved in the biosynthesis of mycocerosyl lipids e.g. Mycobacterium tuberculosis probable mycocerosic acid synthase Rv2940c TR:P96291 (EMBL:Z83858) (2111 aa); Fasta score E(): 0, 60.8% identity in 2127 aa overlap and Mycobacterium bovis mycocerosic acid synthase SW:MCAS_MYCBO (Q02251) (2110 aa); Fasta score E(): 0, 58.8% identity in 2127 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase [...] (2118 aa)
masPutative mycocerosic synthase; Similar to many polyketide synthases from M. tuberculosis e.g. Rv2940c, mas, mycocerosic acid synthase, TR:P96291 (EMBL:AL123456) (2111 aa); Fasta score E(): 0, 88.0% identity in 2119 aa overlap. Similar to Mycobacterium bovis mas, mycocerosic acid synthase, SW:MCAS_MYCBO (Q02251) (2110 aa); Fasta score E(): 0, 85.1% identity in 2122 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transf [...] (2116 aa)
ML0135Similar to many polyketide synthases from M. tuberculosis e.g. N-terminus is similar to Rv2947c, pks15, probable polyketide synthase, TR:P96284 (EMBL:Z83858) (496 aa); Fasta score E(): 0, 90.5% identity in 485 aa overlap and the remainder is similar to Rv2946c, pks1, probable polyketide synthase, TR:P96285 (EMBL:Z83858) (1616 aa); Fasta score E(): 0, 82.5% identity in 1620 aa overlap. Similar to many others e.g. Streptomyces noursei NysC, nystatin biosynthesis polyketide synthase, TR:AAF71776 (EMBL:AF263912) (11096 aa); Fasta score E(): 0, 50.2% identity in 2161 aa overlap. Contains Pf [...] (2103 aa)
ML2357Polyketide synthase; Highly similar to many Prokaryotic and Eukaryotic polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthase rv2931 SW:PPSA_MYCTU (Q10977) (1876 aa) fasta scores: E(): 0, 76.1% id in 1888 aa and to Penicillium patulum 6-methylsalicylic acid synthase SW:MSAS_PENPA (P22367) (1774 aa) fasta scores: E(): 0, 33.8% id in 1823 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains 2 Pfam matches to entry PF00550 pp-binding, Phosphopantethe [...] (1871 aa)
ML2355Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00133 Zinc carboxypeptidases. Contains PS00606 Beta-ketoacyl [...] (2201 aa)
ML2354Similar to many polyketide synthases e.g.Mycobacterium tuberculosis Rv2934 TR:P96203 (EMBL:Z83857) (1827 aa) fasta scores: E(): 0, 80.3% id in 1836 aa, and to Mycobacterium bovis mycocerosic acid synthase SW:MCAS_MYCBO (Q02251) (2110 aa) fasta scores: E(): 0, 32.7% id in 2136 aa. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site. Contains PS00012 Phosphopantetheine attachment site. Contains PS00017 ATP/G [...] (1822 aa)
Your Current Organism:
Mycobacterium leprae
NCBI taxonomy Id: 272631
Other names: M. leprae TN, Mycobacterium leprae TN, Mycobacterium leprae str. TN, Mycobacterium leprae strain TN
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