STRINGSTRING
pts-2 pts-2 pts pts glpK glpK pfk pfk pyk pyk lplA lplA ackA ackA kdtB kdtB ptsI ptsI crr crr dhaK2 dhaK2 MSC_0277 MSC_0277 thiI thiI MSC_0287 MSC_0287 nadK nadK MSC_0304 MSC_0304 pkn pkn ribF ribF polC polC cdsA cdsA MSC_0388 MSC_0388 MSC_0395 MSC_0395 cmk cmk nadD nadD MSC_0444 MSC_0444 dnaG dnaG relA relA MSC_0481 MSC_0481 lplA-2 lplA-2 dinP dinP udk udk acpS acpS pyrH pyrH pts-3 pts-3 fruK fruK MSC_0664 MSC_0664 pgk pgk polA-2 polA-2 dnaE dnaE arcC arcC rpoA rpoA adk adk dhaK1 dhaK1 pts-4 pts-4 frvB frvB fruB fruB suk suk frvA frvA frvB-2 frvB-2 ptsG-3 ptsG-3 glk glk arcC-2 arcC-2 ptsG-4 ptsG-4 glk-2 glk-2 arcC-3 arcC-3 pgsA pgsA ptsK ptsK MSC_0945 MSC_0945 prs prs galU-2 galU-2 rpoB rpoB rpoC rpoC dnaN dnaN EIIA-mtl EIIA-mtl EIIBC-mtl EIIBC-mtl holB holB tmk tmk dnaX dnaX ptsG ptsG polA polA coaE coaE ribC/ribF ribC/ribF galU galU nagE nagE MSC_0133 MSC_0133 tdk tdk cls cls ptsG-2 ptsG-2 gmk gmk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pts-2PTS system, IIA component. (149 aa)
ptsPTS system, sucrose-specific IIC component (trunca; Truncated. (377 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (505 aa)
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (363 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
lplALipoate protein ligase. (334 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (393 aa)
kdtBPANTETHEINE-PHOSPHATE ADENYLYLTRANSFERASE; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (140 aa)
ptsIPHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (573 aa)
crrPTS SYSTEM, GLUCOSE-SPECIFIC IIA COMPONENT. (154 aa)
dhaK2Glycerone kinase. (208 aa)
MSC_0277CONSERVED HYPOTHETICAL PROTEIN. (138 aa)
thiIThiamin biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (395 aa)
MSC_0287Conserved hypothetical transmembrane protein. (629 aa)
nadKHYPOTHETICAL PROTEIN; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (265 aa)
MSC_0304CONSERVED HYPOTHETICAL PROTEIN. (222 aa)
pknSerine/threonine protein kinase. (371 aa)
ribFRiboflavin kinase; Truncated. (184 aa)
polCDNA polymerase III alpha chain; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1482 aa)
cdsAPhosphatidate cytidylyltransferase; Belongs to the CDS family. (341 aa)
MSC_0388Deoxyguanosine kinase. (205 aa)
MSC_0395Conserved hypothetical transmembrane protein. (602 aa)
cmkCytidylate kinase. (222 aa)
nadDProbable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (367 aa)
MSC_0444Deoxynucleoside kinase. (214 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (612 aa)
relAGTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (750 aa)
MSC_0481PREDICTED KINASE RELATED TO HYDROXYACETONE KINASE. (547 aa)
lplA-2Lipoate-protein ligase A. (345 aa)
dinPDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (402 aa)
udkUridine kinase; Belongs to the uridine kinase family. (205 aa)
acpSHolo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (110 aa)
pyrHUridylate kinase; Truncated. (172 aa)
pts-3PTS system, sucrose-specific IIBC component. (628 aa)
fruK1-phosphofructokinase; Truncated. (124 aa)
MSC_0664Conserved hypothetical protein. (226 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (404 aa)
polA-2DNA POLYMERASE I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (911 aa)
dnaEDNA polymerase III alpha chain. (987 aa)
arcCCarbamate kinase; Belongs to the carbamate kinase family. (310 aa)
rpoADNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (317 aa)
adkADENYLATE KINASE; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (213 aa)
dhaK1Glycerone kinase. (332 aa)
pts-4PTS system, trehalose-specific IIBC component. (535 aa)
frvBPTS system, fructose-specific IIBC component. (678 aa)
fruB1-PHOSPHOFRUCTOKINASE; Belongs to the carbohydrate kinase PfkB family. (311 aa)
sukSugar kinase, ROK family. (297 aa)
frvAPTS system, fructose-specific IIA component. (152 aa)
frvB-2PTS system, fructose-specific IIBC component. (613 aa)
ptsG-3PTS system, glucose-specific IIBC component. (676 aa)
glkGLUCOKINASE. (261 aa)
arcC-2Carbamate kinase; Belongs to the carbamate kinase family. (310 aa)
ptsG-4PTS system, glucose-specific, IIBC component. (676 aa)
glk-2GLUCOKINASE; Truncated. (242 aa)
arcC-3Carbamate kinase; Belongs to the carbamate kinase family. (301 aa)
pgsACDPdiacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (206 aa)
ptsKHpr serine kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon source [...] (313 aa)
MSC_0945Conserved hypothetical protein. (319 aa)
prsRibose-phosphate pyrophosphokinase. (357 aa)
galU-2UTP-glucose-1-phosphate uridylyltransferase. (290 aa)
rpoBDNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1291 aa)
rpoCDNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1255 aa)
dnaNDNA POLYMERASE III, BETA CHAIN. (375 aa)
EIIA-mtlPTS SYSTEM, MANNITOL-PERMEASE IIA COMPONENT. (142 aa)
EIIBC-mtlPTS SYSTEM, MANNITOL-PERMEASE IIBC COMPONENT. (520 aa)
holBDNA polymerase III delta subunit. (246 aa)
tmkTHYMIDYLATE KINASE; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa)
dnaXDNA polymerase III gamma-tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (652 aa)
ptsGPTS system, glucose-specific IIABC component. (580 aa)
polADNA POLYMERASE I, 5'-3' exonuclease. (304 aa)
coaEDEPHOSPHO-COA KINASE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (189 aa)
ribC/ribFRiboflavin kinase / FAD synthetase. (250 aa)
galUUTP-GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE. (290 aa)
nagEPTS system, N-acetylglucosamine-specific IIBC component. (557 aa)
MSC_0133Hypothetical protein. (142 aa)
tdkThymidine kinase. (209 aa)
clsCardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (509 aa)
ptsG-2PTS SYSTEM, GLUCOSE-SPECIFIC IIBC COMPONENT; Truncated. (177 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (297 aa)
Your Current Organism:
Mycoplasma mycoides
NCBI taxonomy Id: 272632
Other names: M. mycoides subsp. mycoides SC str. PG1, Mycoplasma mycoides subsp. mycoides SC str. PG1, Mycoplasma mycoides subsp. mycoides SC strain PG1
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