| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ileS | leuS | MPN_520 | MPN_384 | isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | leucyl-tRNA synthetase; MPN384(new), 454(Himmelreich et al., 1996); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.944 |
| ileS | valS | MPN_520 | MPN_480 | isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.857 |
| leuS | ileS | MPN_384 | MPN_520 | leucyl-tRNA synthetase; MPN384(new), 454(Himmelreich et al., 1996); Belongs to the class-I aminoacyl-tRNA synthetase family. | isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | 0.944 |
| leuS | pdhD | MPN_384 | MPN_390 | leucyl-tRNA synthetase; MPN384(new), 454(Himmelreich et al., 1996); Belongs to the class-I aminoacyl-tRNA synthetase family. | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes. | 0.490 |
| leuS | valS | MPN_384 | MPN_480 | leucyl-tRNA synthetase; MPN384(new), 454(Himmelreich et al., 1996); Belongs to the class-I aminoacyl-tRNA synthetase family. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.819 |
| nox | pdhB | MPN_394 | MPN_392 | NADH oxidase; Catalyzes the four-electron reduction of molecular oxygen to water. | Pyruvate dehydrogenase E1-beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.885 |
| nox | pdhD | MPN_394 | MPN_390 | NADH oxidase; Catalyzes the four-electron reduction of molecular oxygen to water. | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes. | 0.774 |
| pdhB | nox | MPN_392 | MPN_394 | Pyruvate dehydrogenase E1-beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | NADH oxidase; Catalyzes the four-electron reduction of molecular oxygen to water. | 0.885 |
| pdhB | pdhD | MPN_392 | MPN_390 | Pyruvate dehydrogenase E1-beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes. | 0.999 |
| pdhD | leuS | MPN_390 | MPN_384 | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes. | leucyl-tRNA synthetase; MPN384(new), 454(Himmelreich et al., 1996); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.490 |
| pdhD | nox | MPN_390 | MPN_394 | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes. | NADH oxidase; Catalyzes the four-electron reduction of molecular oxygen to water. | 0.774 |
| pdhD | pdhB | MPN_390 | MPN_392 | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes. | Pyruvate dehydrogenase E1-beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.999 |
| valS | ileS | MPN_480 | MPN_520 | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | 0.857 |
| valS | leuS | MPN_480 | MPN_384 | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | leucyl-tRNA synthetase; MPN384(new), 454(Himmelreich et al., 1996); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.819 |